A5058073675- Prostate Cancer Treatment and Research
- Cancer-related Molecular Pathways
- Growth Hormone and Insulin-like Growth Factors
- Endometrial and Cervical Cancer Treatments
- Estrogen and related hormone effects
- Diet and metabolism studies
- Immune Cell Function and Interaction
- Salivary Gland Disorders and Functions
- Cytomegalovirus and herpesvirus research
- Oral microbiology and periodontitis research
- Ovarian cancer diagnosis and treatment
- Toxoplasma gondii Research Studies
- Cytokine Signaling Pathways and Interactions
- Cancer Risks and Factors
- Vitamin C and Antioxidants Research
- Parvovirus B19 Infection Studies
- Pharmacology and Obesity Treatment
- Retinoids in leukemia and cellular processes
- Cancer-related molecular mechanisms research
- Body Image and Dysmorphia Studies
- Health and Lifestyle Studies
- Adrenal Hormones and Disorders
- Cervical Cancer and HPV Research
- Hedgehog Signaling Pathway Studies
- Bipolar Disorder and Treatment
Universidad de Guadalajara
2013-2024
Tepatitlán's Institute for Theoretical Studies
2015
Skin cancer is a disease marked by the presence of abnormal cells within skin tissues. These grow in disorganized manner and reproduce uncontrollably at rapid pace. Various factors contribute to onset progression cancer; these can be genetic environmental, psychological, microbiological, immunological, such as inflammation weakened immune system. Signal transducers activators transcription (STATs) are family latent activated response various cytokines growth factors. This study aims identify...
The altered expression of prolactin (PRL) and its receptor (PRLR) has been implicated in breast other types cancer. There are few studies that have focused on the analysis PRL/PRLR cervical cancer where development neoplastic lesions is influenced by variation hormonal status. aim this study was to evaluate effect PRL treatment cell proliferation apoptosis lines.High multiple PRLR forms PRLvariants 60-80 kDa were observed lines compared with non-tumorigenic keratinocytes evaluated Western...
Prostate cancer (PCa) is the most prevalent cause of death in male population worldwide. The G Protein-Coupled Estrogen Receptor (GPER) has been gaining relevance development PCa. Hedgehog (Hh) pathway activation associated with aggressiveness, metastasis, and relapse PCa patients. To date, no studies have evaluated crosstalk between GPER Hh along different group grades We conducted an analysis paraffin-embedded tissues derived from patients prognostic grade using immunohistochemistry....
Prolactin (PRL) has been implicated in the development of different types cancer. However, signaling pathways might be activated depending on various forms prolactin receptor (PRLR). JAK/STAT is an important pathway associated with PRL effects. The activation activate antiapoptotic genes that could importantly lead to progression tumorigenesis. Recently, we have reported cell survival by inhibition apoptosis and precise for this process are still questioned. purpose study was evaluate...
Cervical cancer (CC) is the second most common in less developed countries and leading cause of death by women worldwide. The 99% CC patients are infected with Human Papilloma Virus (HPV), being HPV16 HPV18 infection frequent. Even though HPV considered to be a necessary factor for development CC, it not enough, as requires participation other factors such hormonal ones. Several studies have demonstrated requirement estrogen its receptors (ERα, ERβ, GPER) precursor lesions progress towards...
Estrogens and estrogen receptors (ERs), such as ERα ERβ, prolactin (PRL) receptor (PRLR) have been reported to be involved in the physiopathology of uterine cervical cancer (UCC). The 60 kDa PRL is an isoform PRL, which produced by UCC‑derived cells. present study aimed evaluate expression hormonal different degrees lesions, determine whether 17β‑estradiol (E2) modulated cell survival metabolism UCC cells, HaCaT cells transduced with human papillomavirus (HPV) 16 18 E6/E7 oncogenes. ERα,...
The effect of estrogen has been traditionally studied through the modulation its alpha and beta nuclear receptors; however, G Protein-Coupled Estrogen Receptor (GPER) recently involved in pathology numerous tumors. Although study GPER cervical cancer begun, contribution still remains to be completely evaluated.The purpose this work was determine expression receptor different degrees lesions whether stimulation with specific agonist (G-1) modulated mechanisms cell survival or death...
Epstein-Barr Virus (EBV) infection prevails in underdeveloped and developing countries. The tonsils seem to be candidate replication sites for EBV some studies have exposed a close association among viral infections chronic tonsillitis. objective of this study was identifying the prevalence Mexican patients who had undergone tonsillectomy because tonsillitis.Frozen tissues medical records were obtained from 50 patients. DNA extracted subjected PCR amplify EBER-2 region EBV. Next, classified...
Obesity is the result of a complex combination psychological, biological, and environmental factors. In this work, we evaluate whether obesity related to eating habits, depressive symptomatology, as well interleukin-8 cortisol. A descriptive cross-sectional study was carried out in 232 university students. All youths were surveyed determine their habits symptomatology. Anthropometric measures blood sample taken its biochemical profile concentration The results show that increase overfat...
El cáncer de próstata (CaP) es la segunda enfermedad más frecuente a nivel mundial según Organización Mundial Salud (OMS). Uno los mayores desafíos en métodos tratamiento el control metástasis; por lo tanto, para comprender mejor proceso señalización, nos centramos Receptor Acoplado Proteína G Estrógenos (GPER), cual ha sido relevante desarrollo del CaP. Hasta fecha, pocos informes sugieren que GPER induce vías señalización; sin embargo, su participación aún no esclarecida Objetivo: Evaluar...
This study examined the association between tumour necrosis factor-alpha (TNF- α) (-308 G/A) polymorphism and gingivitis, serum salivary TNF- α levels, in a Mexican population.This enrolled 171 subjects, divided into two groups: healthy subjects gingivitis patients. gene was analyzed by PCR-RFLP assay. Salivary samples were used to measure cytokine levels through ELISA technique.TNF- shown have protective effect carriers of A/A genotype allele A. The G/A is associated with an increase...
Background: many genes have been involved in the development of obesity. Interleukin 32 (IL-32) is a proinflammatory cytokine; rs45499297 T/C promoter, single-nucleotide polymorphism IL32 gene. Objectives: this study aimed to evaluate and its association with Another objective was carry out an silico analysis. Methods: cross-sectional, included 333 subjects classified by body mass index fat percentage. The plasma glucose lipid profile were measured. We measured serum IL-32 protein ELISA...
Abstract BackgroundEnvironmental psychological factors such as mood states can modify and trigger an organic response; depressive disorder is considered a risk factor for oncological development, leading to alterations both in the genesis progression of disease. Some authors have identified that personality relates since high score neuroticism associated with intense long-lasting emotions stress therefore development behaviors. The objective this study was analyze relationship between...
This review explores the role of G protein-coupled estrogen receptor (GPER) and its interaction with mitogen-activated protein kinase (MAPK)/extracellular regulated (ERK), phosphatidylinositol 3-kinase (PI3K)/AKT, hedgehog (Hh) signaling pathways in prostate cancer (PCa) progression.PCa is a significant health problem globally, GPER has been shown to play crucial regulation cell proliferation survival PCa cells.The MAPK/ERK pathway, activated by GPER, involved growth differentiation, while...