A5100742073- Systemic Lupus Erythematosus Research
- Advances in Oncology and Radiotherapy
- Spinal Cord Injury Research
- Innovative Teaching Methods
- Colorectal Cancer Treatments and Studies
- Oral health in cancer treatment
- Genetic factors in colorectal cancer
- Radiation Therapy and Dosimetry
- Drug-Induced Ocular Toxicity
- Hepatocellular Carcinoma Treatment and Prognosis
- Infectious Diseases and Mycology
- Bone fractures and treatments
- Nerve injury and regeneration
- Orthopedic Surgery and Rehabilitation
- Ocular Diseases and Behçet’s Syndrome
- Facial Nerve Paralysis Treatment and Research
- Cutaneous Melanoma Detection and Management
- Advanced Radiotherapy Techniques
- Cytokine Signaling Pathways and Interactions
- Amoebic Infections and Treatments
- Innovations in Educational Methods
- Trauma Management and Diagnosis
- Lung Cancer Diagnosis and Treatment
- Hip and Femur Fractures
- Pain Mechanisms and Treatments
Harbin Medical University
2017-2025
First Affiliated Hospital of Harbin Medical University
2017-2025
Guangzhou Medical University
2012-2024
Second Affiliated Hospital of Guangzhou Medical University
2012-2024
Hebei University of Engineering
2022
Affiliated Hospital of Hebei University
2022
Inner Mongolia Medical University
2022
Wuhan Hankou Hospital
2021
Center for Excellence in Molecular Cell Science
2020
University of Chinese Academy of Sciences
2020
Abstract The mechanisms of injury‐induced apoptosis neurons within the spinal cord are not understood. We used a model peripheral nerve‐spinal injury in rat and mouse to induce motor neuron degeneration. In this animal model, unilateral avulsion sciatic nerve causes neurons. tested hypothesis that p53 Bax regulate neuronal apoptosis, DNA damage is an early upstream signal. Adult mice rats received avulsions causing lumbar achieve endstage at 7–14 days postlesion. This blocked bax −/− mice....
Introduction: Limited treatment options are available for residual locally advanced cervical cancer after concurrent radio-chemotherapy. Pembrolizumab has been approved by the US Food and Drug Administration to treat patients with persistent, recurrent, metastatic cancer. However, it is expensive not covered medical insurance in China. Case Description: A patient presented stage IIIC1 characterized PTEN, PIK3CA, MTOR, ARID1A mutations, accompanied low programmed cell death-ligand 1...
Objectives: To analyse the failure patterns and prognostic factors influencing survival in patients with primary mucosal melanoma of nasal cavity paranasal sinuses.Materials methods: Fifty-one were analysed retrospectively. Forty-eight, 33, 10, 13 underwent surgery, radiotherapy, chemotherapy, immunotherapy, respectively. Failure events, including local recurrence, regional relapse, distant metastases, death, examined.Results: During follow-up (median: 59.0 months), 36 experienced after...
Objective: To investigate the incidence and risk factors for liver abscess formation after treatment with drug-eluting bead chemoembolization (DEB-TACE) in patients metastatic hepatic tumors (MHT). Methods: The current study is a retrospective analysis of clinical data 137 who received DEB-TACE our institute (Union Hospital, Tongji Medical College, Huazhong University Science Technology) between June 2015 September 2020. Patients were evaluated presence or absence post-DEB-TACE abscess....
Background: We evaluated the feasibility of CEA/CK20 mRNA and CEA/CA19-9 proteins as tumor markers for colorectal cancer by detecting tumor-specific mRNAs in circulating cells secreted peripheral blood patients. Patients Methods: Peripheral was obtained from 23 healthy volunteers 46 patients on day initiation adjuvant chemotherapy after surgery (stages I–III, n = 27) or first diagnosis (stage IV, 19). Levels mononuclear (PBMCs) were determined with quantitative real-time reverse...
Objective To evaluate the dosimetric effects of air cavity on primary tumor and organs at risk (OARs) during intensity-modulated radiation therapy (IMRT) for nasopharyngeal carcinoma patients. Methods Nine patients with had CT simulation before treatment 25 fraction radiotherapy. Radiotherapy plan1 was first created by delineating target volumes OARs image, which then copied merged second image. Air that formed following volume regression delineated density set to zero. A new gross...
Background: In systemic lupus erythematosus (SLE), retinopathy is connected to severe disease and poorer prognosis. This study aimed investigate changes in retinal vascular density (VD) SLE nephritis (LN) patients examine the effects of Belimumab hydroxychloroquine (HCQ) on VD these patients. Methods: cross-sectional enrolled 54 (21 with LN 33 without LN). A comprehensive ophthalmological evaluation using optical coherence tomography angiography (OCTA) was conducted Rheumatological...
Abstract Background Class attendance is important for academic performance. Personal interactions between teachers and students are difficult in large classes; the number of medical undergraduate China ranges from dozens to over 100. It control teaching process improve student participation. Methods Two classes fourth-year students, with each class comprising 115 participated study. One class, trial group, was taught by block-based method based on cybernetics. This study conducted three...
Abstract Purpose: To evaluate microvasculature alterations of the peripapillary retina (PR) and macula to assess if changes can detect preclinical retinopathy in systemic lupus erythematosus (SLE) patients. Methods: Cross-sectional study 32 SLE patients without 22 normal controls. Optical coherence tomography angiography was used measure PR macula. Vessel densities (VD, %) fractal dimensions superficial capillary plexus (SCP) deep (DCP) were calculated. Results: Compared controls, macular VD...
Abstract Background: The number of medical undergraduate students in Chinese college classes ranges from dozens to over 100. As a result, the interaction between teacher and is difficult conduct. Student attendance participation need be improved. Methods: Two fourth-year students, with each class comprising 115 participated study. One was trial group taught by block-based teaching method based on cybernetics. This study conducted three courses Introduction Oncology. course included several...
Objective To investigate the effect of two different nerve block anesthesia on clavicle fracture fixation.Methods 52 cases clavicular fixation were randomly divided into groups (n =26):cervical plexus group (group A),Brachial B).Non-invasive blood pressure (NIBP),heart rate (HR),oxygen saturation (SpO2) and electrocardiogram (ECG) observed before anesthesia,incision,and fractures.We analyzed anesthetic in points time.Results ①Compared with B,three time NIBP HR A statistically significant(P ＜...
Internal jugular vein placement is frequently utilized in clinical practice for rapid infusion, intraoperative monitoring, peritoneal dialysis, and access interventions. Additionally, the process may lead to complications like hematoma, infection, misdirection of artery, pneumothorax, arteriovenous fistula. In case described this report, all vascular ruptures effectively were repaired because when internal was adopted, a dialysis catheter would go through right into subclavian then ascending...