A5047918461- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Brucella: diagnosis, epidemiology, treatment
- Tryptophan and brain disorders
- COVID-19 Clinical Research Studies
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Pneumonia and Respiratory Infections
- Anesthesia and Neurotoxicity Research
- Aeolian processes and effects
- Lung Cancer Research Studies
- Nutritional Studies and Diet
- Parkinson's Disease Mechanisms and Treatments
- Burkholderia infections and melioidosis
- Galectins and Cancer Biology
- Cardiovascular Disease and Adiposity
- Genomics, phytochemicals, and oxidative stress
- Intensive Care Unit Cognitive Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer-related Molecular Pathways
- Cancer Research and Treatments
- Cardiovascular Function and Risk Factors
- Glycogen Storage Diseases and Myoclonus
- Diabetes Treatment and Management
- Regulation of Appetite and Obesity
Inner Mongolia Medical University
2022-2025
Shanghai Tenth People's Hospital
2022-2024
Tongji University
2021-2024
Mongolian National University of Medical Sciences
2023-2024
Shandong University of Traditional Chinese Medicine
2022-2024
Chengde Medical University
2024
Chinese Academy of Sciences
2021-2023
First Affiliated Hospital of Zhengzhou University
2023
Guangzhou Regenerative Medicine and Health Guangdong Laboratory
2021-2023
Shanghai Jiao Tong University
2021-2023
Abstract Aim The association between composite dietary antioxidant index (CDAI) and diabetes remains unknown. Our study was to investigate the of CDAI with diabetes. Methods A total 11,956 participants were enrolled from National Health Nutrition Examination Surveys (NHANES). calculated intake six antioxidants. Multivariable logistic regressions performed explore associations prevalence glycemic index. Non-linear explored using restricted cubic splines. Results In multivariate regression...
Idiopathic pulmonary fibrosis (IPF) is the most common type of interstitial pneumonia. Lung cancer, mainly non-small cell lung cancer (NSCLC), a complication idiopathic fibrosis. IPF also an independent risk factor cancer. Some studies have shown that complement system can promote progression In addition, C1q has demonstrated to exert tumor-promoting effect in many tumors. However, role and still remain unclear.We selected differentially expressed genes using datasets from GEO, investigated...
Brucellosis, a zoonotic infectious disease caused by the Brucella genus, remains significant global public health concern, with Inner Mongolia, China, being notable hotspot affecting both human and livestock. In response to this, we developed dynamic SEIVWShIahIch model simulate transmission of brucellosis in Mongolia. We calculated basic reproduction number (R0 = 2.86), indicating severe epidemic trend cases expected increase over coming decades. The was fitted data, key parameters were...
Tuberculosis (TB) remains one of the most serious infectious diseases worldwide. China has second highest TB burden globally, but existing studies have mostly neglected post-tuberculosis (post-TB) disease burden. This study estimated and post-TB in Inner Mongolia, China, from 2016 to 2018.Population data were collected Information Management System. Post-TB was defined as caused by Chronic Obstructive Pulmonary Disease (COPD) occurring after patients with cured. To estimate incidence rate...
Background The transient receptor potential vanilloid (TRPV) channels family, TRPV1-6, has been identified to profoundly affect a wide spectrum of pathological processes in various cancers. However, the biological function and prognostic value TRPVs clear cell renal carcinoma (ccRCC) are still largely unknown. Methods We obtained gene expression data clinical information 539 ccRCC patients from Cancer Genome Atlas (TCGA) database. A series databases were used for processing visualization,...
Premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome (PMS), is serious health that affects patient moods. It caused by cyclic psychological symptoms and its pathogenesis still unclear. Abnormalities in the basolateral amygdala (BLA) orexin system, which are important causes development depressive mood, have not been reported PMDD, so exploring intrinsic mechanisms meaningful for enriching pathomechanisms PMDD.
Rotational atherectomy (RA) is the major tool used to treat severely calcified lesions in patients with coronary artery disease (CAD). The relationship between microvascular dysfunction and RA remains unknown. Therefore, we attempted explore predictive implications of angiography-derived index microcirculatory resistance (angio-IMR) CAD undergoing RA.
Anxiety disorder is one of the most common mental diseases. It mainly characterized by a sudden, recurring but indescribable panic, fear, tension and/or anxiety. Yangshendingzhi granules (YSDZ) are widely used in treatment anxiety disorders, its active ingredients and underlying mechanisms not yet clear. This study integrates network pharmacology metabolomics to investigate potential mechanism action YSDZ rat model First, targets were screened pharmacology. Then, predictions verified...
Coronary microvascular dysfunction is crucial in determining myocardial ischemia; however, the relationship between epicardial coronary diameter stenosis (DS) and index of microcirculatory resistance (IMR) remains unclear. We sought to explore distribution angiography-derived IMR (angio-IMR) patients with suspected ischemia.The study included 480 ischemia, all whom underwent angiography. According severity DS, were divided into three groups: mild (DS < 50%), intermediate 50%-70%), severe >...
Although uveal melanoma (UM) at the early stage is controllable to some extent, it inevitably ultimately leads death due its metastasis. At present, difficulty that there no way effectively tackle It hypothesized these will be treated by target molecules, but recognized molecule has not yet been found. In this study, was explored through proteomics.Transgenic enhanced green fluorescent protein (EGFP) inbred nude mice, which spontaneously display a tumor microenvironment (TME), were used as...
Objective: To evaluate the prognostic value of different timepoint and threshold systolic blood pressure (SBP) Time in Target Rang (TTR) Major Adverse Cardiovascular Events (MACEs). Method: A post-hoc analysis SPIRNT trial was conducted. Participants with complete BP data no adverse events occurred next 2-years follow-up were enrolled. SBP TTR calculated at timepoints (3, 12, 24 months) thresholds (110-130mmHg; 110-140mmHg; 110-130mmHg for intensive 120-140mmHg standard treatment groups)(Fig...
Compound 1 was previously identified by our team as a glycogen phosphorylase (GP) inhibitor with glucose-lowering activity and demonstrated to have protective effects against myocardial cerebral ischemia. However, its impact on muscle function has not been clarified. This study is the first evaluate long-term of GP inhibitors metabolism. After 28-day administration 1, we performed assays assess biochemical parameters in rats. We observed reductions peak holding force, duration, tetanic...
<title>Abstract</title> Brucellosis, a zoonotic infectious disease caused by the Brucella genus, remains significant global public health concern, with Inner Mongolia, China, being notable hotspot affecting both human and livestock. In response to this, we developed dynamic <italic>SEIVWS</italic><sub><italic>h</italic></sub><italic>I</italic><sub><italic>ah</italic></sub><italic>I</italic><sub><italic>ch</italic></sub> model simulate transmission of brucellosis in Mongolia. We calculated...
There is no consensus on optimal time points or systolic blood pressure (SBP) ranges for calculating SBP in target range (TTR).
This study aimed to investigate the prognostic value of age and blood pressure stratified healthy vascular aging (HVA) defined in North Shanghai Study (NSS), illustrate its relationship with organ damage (OD).
Abstract DNA methylation modification has been proved to play an important role in heart diseases. In this study, the of Ten-Eleven Translocation-2 (TET2), which is a key demethylation enzyme, investigated cardiac remodeling. TET2 abundant endothelial cells but decreased hypertrophic hearts. knockdown triggers endothelial-to-mesenchymal transition (EndMT), while overexpression inhibits EndMT. vivo, Cdh5-CreERT2/TET2 flox/flox ; Rosa26-mTmG +/- mice are developed and undergo transverse aortic...
Objective: Controversy exists in the comparison between central and peripheral blood pressure (BP) prediction of cardiovascular all-cause mortality. To examine whether BP predicts mortality better than brachial a large cohort elderly Chinese. Design method: A total 3050 participants enrolled Northern Shanghai Study, prospective study focusing on risk community-dwelling Chinese living north Shanghai, China 2014 2019, were included. Central was estimated tonometrically from redial pulse...
Telemedicine and blood pressure (BP) self-monitoring conduces to management of hypertension. Recent hypertension guidelines highly recommended single-pill-combination (SPC) for the initial treatment essential Based on this fact, an SPC-based telemedicine titration regimen with BP could be a better way in managing This trial aims elucidate whether combined is superior alone during management.This study will multi-centered, open-labelled, randomized controlled trial. A minimum sample 358...
Aim: To investigate prevention measures of hospital-acquired infection and clinical features suspicious COVID-19 patients in the pediatric respiratory ward. Methods: Patients with fever cough or accompanied by vomiting diarrhea were given pre-isolation measures. The medical records collected analyzed to summarize patients’ features. Results: A total 50 pre-isolated children hospitalized between January 28 March 5, 2020 included in. Pre-isolation combined epidemiological history pathogen...