- Cytomegalovirus and herpesvirus research
- Pregnancy and Medication Impact
- Inflammatory Bowel Disease
- Pneumocystis jirovecii pneumonia detection and treatment
- Eosinophilic Esophagitis
- Polyomavirus and related diseases
- COVID-19 Clinical Research Studies
- Lung Cancer Diagnosis and Treatment
- Herpesvirus Infections and Treatments
- Transportation Planning and Optimization
- Dental Education, Practice, Research
- Platelet Disorders and Treatments
- Antifungal resistance and susceptibility
- Pneumonia and Respiratory Infections
- Fungal Infections and Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Intramuscular injections and effects
- Respiratory viral infections research
- Traffic Prediction and Management Techniques
- Dialysis and Renal Disease Management
- Antibiotics Pharmacokinetics and Efficacy
- Reproductive System and Pregnancy
- Transportation and Mobility Innovations
- Venous Thromboembolism Diagnosis and Management
- COVID-19 and healthcare impacts
Royal Adelaide Hospital
2012-2025
Flinders Medical Centre
2017-2024
GlaxoSmithKline (United States)
2024
The University of Adelaide
2015-2023
University Hospitals Birmingham NHS Foundation Trust
2021-2022
Massachusetts General Hospital
2014-2022
Harvard University
2020-2022
Poole Hospital
2017
National Grid (United Kingdom)
2015
Concord Hospital
2012
Patients without human immunodeficiency virus (HIV) are increasingly recognized as being at risk for cryptococcosis. Knowledge of characteristics cryptococcosis in these patients remains incomplete.We conducted a retrospective study 46 Australian and New Zealand hospitals to compare its frequency with HIV describe HIV. between January 2015 December 2019 were included.Of 475 cryptococcosis, 90% (426 475) marked predominance both Cryptococcus neoformans (88.7%) gattii cases (94.3%). Most...
COVID-19 infection varies in severity from minimal symptoms to critical illness associated with a hyperinflammatory response. Data on disease progression immunosuppressed solid organ transplant (SOT) recipients are limited.We examined the electronic medical records of all SOT 12 Massachusetts hospitals between February 1, and May 6, 2020. We analyzed demographics, clinical parameters, course, outcomes these patients.Of 52 COVID-19-positive patients, 77% were hospitalized 35% required ICU...
Purpose Coronavirus disease-2019 (COVID-19) is associated with a wide spectrum of clinical symptoms including acute respiratory failure. Biomarkers that can predict outcomes in patients COVID-19 assist patient management. The aim this study to evaluate whether procalcitonin (PCT) outcome and bacterial superinfection infected severe syndrome coronavirus-2 (SARS-CoV-2). Methods Adult diagnosed SARS-CoV-2 by nasopharyngeal PCR who were admitted tertiary care center Boston, MA infection between...
Abstract Background There is a limited understanding of the impact coronavirus disease 2019 (COVID-19) on Latinx population. We hypothesized that patients would be more likely to hospitalized and admitted intensive care unit (ICU) than White patients. Methods analyzed all with COVID-19 in 12 Massachusetts hospitals between February 1 April 14, 2020. examined association race, ethnicity, age, reported comorbidities, hospitalization ICU admission using multivariable regression. Results Of 5190...
The COVID-19 pandemic impacted greatest among patients with pre-existing chronic health conditions, including kidney disease. This retrospective cohort study aimed to investigate the 30-day mortality of receiving replacement therapy (KRT) after infection COVID-19, living in Australia and New Zealand between 2020 2022, on haemodialysis (HD), peritoneal dialysis (PD) renal transplant (KT) recipients. is a using data from Australian Dialysis Transplant Registry (ANZDATA). Patients were included...
A 28-year-old male presented to an Australian hospital with sudden-onset headache and seizure following a kidney transplant for end-stage renal disease due IgA nephropathy. Clinical approach the cases management of diagnosed are discussed.
Patients with inflammatory bowel disease (IBD) tend to have smaller family sizes. Health care professionals (HCPs) may inadvertently provide inaccurate advice patients resulting in voluntary childlessness or unfavourable pregnancy outcomes.The study aims objectively measure IBD-specific pregnancy-related knowledge of general practitioners (GPs) and obstetricians/gynaecologists (OB/GYNs) comparison gastroenterologists (GEs) using the validated Crohn's Colitis Pregnancy Knowledge (CCPKnow)...
Electricity demand forecasts are needed for decisions regarding generation dispatch lead times as short just a few minutes. Imbalance between and causes deviation of the system frequency from its target, which in Great Britain is 50 Hz. This, turn, change demand, due largely to motor loads. For Britain, estimated be 2.5% per 1 Hz target. This can used calculate that would have occurred if had been at Modeling forecasting resulting frequency-corrected provides better basis dispatching...
Abstract Infection remains a significant contributor to morbidity and mortality in patients with myeloma. This guideline was developed by multidisciplinary group of clinicians who specialise the management myeloma infection from medical scientific advisory Myeloma Australia National Centre for Infections Cancer. In addition summarising current epidemiology risk factors myeloma, this provides recommendations that address three key areas prevention infection: screening latent infection, use...
A Man with Fever and Shortness of Breath after Liver Transplantation 66-year-old man hypertension, diabetes, hyperlipidemia, obesity, chronic kidney disease, end-stage liver for...
A recent article in the Journal of American Medical Association by Limaye et al1 highlights an emerging role for use letermovir prevention cytomegalovirus (CMV) disease among high-risk kidney transplant recipients. CMV continues to be "troll transplantation" contributing morbidity and graft loss, with recipients (donor seropositive, recipient seronegative, D+R–) developing late after end prophylaxis most significant challenges.2 This study compares novel antiviral standard-of-care...
COVID-19 vaccination represents a key preventative part of the Australian public health approach to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Hospital inpatients are frequently high risk for and death. Anecdotes high-risk being unvaccinated lack electronic medical record (EMR) visibility status prompted present study as these patients could represent themselves, staff, other service provision.To determine uptake vaccine among at an adult tertiary hospital...
Abstract Background Anti-Platelet Factor 4 (PF4) IgG antibodies that activate platelets via FcγRIIa have been shown to be an important part of the pathophysiology vaccine-induced immune thrombocytopenia and thrombosis (VITT). There is now extensive literature on its presentation initial management. no however what happens these patients following discharge. Methods We collected clinical data samples from seven presenting with VITT followed them up for 82-145 days. also at last follow-up....
A 55-year-old man with a history of sarcoidosis was admitted 7 months after kidney transplantation for nephrocalcinosis because fatigue, weight loss, and new pulmonary nodules. diagnostic test performed.
Viana et al1 recently reported an open-label randomized controlled trial of continuation antimetabolite therapy (mycophenolate or azathioprine) versus conversion to sirolimus after the first episode cytomegalovirus (CMV) in seropositive kidney transplant recipients. The primary outcome was recurrence CMV within 12 mo transplant. Although this a small highly selected patients, difference is stark, with no patients (0/35) intervention group (sirolimus conversion) developing infection disease...