Kylie Alcorn

ORCID: 0000-0003-2591-483X
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • SARS-CoV-2 detection and testing
  • Long-Term Effects of COVID-19
  • Orthopedic Infections and Treatments
  • Respiratory viral infections research
  • Urinary Tract Infections Management
  • Infectious Diseases and Tuberculosis
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Antibiotic Use and Resistance
  • Antimicrobial Resistance in Staphylococcus
  • Osteomyelitis and Bone Disorders Research
  • COVID-19 Digital Contact Tracing
  • COVID-19 epidemiological studies
  • Data-Driven Disease Surveillance
  • Fungal Infections and Studies
  • Respiratory Support and Mechanisms
  • Interprofessional Education and Collaboration
  • Hepatitis C virus research
  • Bacterial Identification and Susceptibility Testing
  • Vector-borne infectious diseases
  • Climate Change and Health Impacts
  • Nail Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Patient-Provider Communication in Healthcare

Gold Coast Hospital
2013-2025

Griffith University
2024

Gold Coast Health
2020-2023

To determine the effect of covid-19 vaccination, given before and after acute infection with SARS-CoV-2 virus, or a diagnosis long covid, on rates symptoms covid.Systematic review.PubMed, Embase, Cochrane trials, Europe PubMed Central (Europe PMC) for preprints, from 1 January 2020 to 3 August 2022.Trials, cohort studies, case-control studies reporting patients covid vaccination covid. Risk bias was assessed ROBINS-I tool.1645 articles were screened but no randomised controlled trials found....

10.1136/bmjmed-2022-000385 article EN cc-by-nc BMJ Medicine 2023-02-01

Antibiotics are some of the most commonly prescribed drugs in Emergency Department (ED) and yet data describing overall appropriateness antibiotic prescribing ED is scarce.To describe ED.A retrospective, observational study current practice. All patients who presented to during period were at least one included. Specialists from Infectious Disease, Microbiology Medicine a Senior Pharmacist assessed against evidence-based guidelines.A total 1019 (13.6%) patient presentations involved...

10.1093/jac/dky447 article EN cc-by-nc Journal of Antimicrobial Chemotherapy 2018-10-11

Patients without human immunodeficiency virus (HIV) are increasingly recognized as being at risk for cryptococcosis. Knowledge of characteristics cryptococcosis in these patients remains incomplete.We conducted a retrospective study 46 Australian and New Zealand hospitals to compare its frequency with HIV describe HIV. between January 2015 December 2019 were included.Of 475 cryptococcosis, 90% (426 475) marked predominance both Cryptococcus neoformans (88.7%) gattii cases (94.3%). Most...

10.1093/cid/ciad321 article EN Clinical Infectious Diseases 2023-05-26

Background: Native joint septic arthritis (NJSA) of the hand is poorly studied. Management guidelines are extrapolated from large infections despite differences in epidemiology, anatomy and aetiology. Limited evidence suggests shorter courses antibiotics can achieve outcomes comparable to longer courses. The aim our study characterise presentation, management NJSA an adult cohort Southeast Queensland (SEQ) determine if route or duration affected outcome. Our was compared those literature...

10.1142/s2424835525500201 article EN The Journal of Hand Surgery (Asian-Pacific Volume) 2025-01-05

ObjectiveCOVID-19 affected health care globally. The aim of this study was to investigate the impact COVID-19 on both public and private emergency departments (EDs).MethodsThis a retrospective cohort ED presentations made three two hospital EDs located in one region Queensland. Presentation rates per 1000 population incident rate ratios (IRR) for time periods: T1: pre-pandemic (March-June 2018/2019), T2: initial restrictions 2020), T3: easing 2021) were calculated. Linear trends produced...

10.1071/ah24182 article EN Australian Health Review 2025-01-01

Hemotropic mycoplasmas (hemoplasmas) infect animals and humans can lead to clinical syndromes mainly characterized by hemolytic anemia. A novel pathogen, Candidatus Mycoplasma haemohominis, was recently associated with a case of human hemoplasmosis in Europe. Here we report the first detection this pathogen an Australian patient exhibiting persistent fever, anemia, pancytopenia over 10-month period.After exhaustive negative testing for infectious diseases, whole genome sequencing (WGS)...

10.1093/cid/ciaa089 article EN Clinical Infectious Diseases 2020-01-31

Naturally acquired immunity to malaria is robust and protective against all strains of the same species Plasmodium . This develops as a result repeated natural infection, taking several years develop.

10.1128/iai.00587-18 article EN cc-by Infection and Immunity 2018-10-12

Infective endocarditis (IE) complicates up to a quarter of Staphylococcus aureus bacteraemia (SAB) cases. Risk scores predict IE complicating SAB but have undergone limited external validation, especially in community-acquired infections and those who use IV drugs. Addition the time positive culture (TTP) may provide incremental risk prognostication.To externally validate for predicting assess value TTP.The modified Duke score was calculated adults hospitalized with at major tertiary...

10.1093/jac/dkac129 article EN Journal of Antimicrobial Chemotherapy 2022-04-14

During the coronavirus disease 2019 (COVID-19) epidemic, continued presence of viral RNA in upper airways infected people has been reported.1 Such persistence does not necessarily signify active infection or that virus can be transmitted.2 In Queensland, repeat testing for severe acute respiratory syndrome 2 (SARS-CoV-2) with an initial positive test result was undertaken until June 2020, providing opportunity to explore patterns positivity, apparent rates clearance RNA, and extent which...

10.5694/mja2.51036 article EN The Medical Journal of Australia 2021-04-26

Abstract Background Clinical characteristics and outcomes of coronavirus disease 2019 (COVID‐19) patients have been varied internationally but not studied in an Australian cohort. Aim To describe approximately the first 200 documented COVID‐19 cases during outbreak Gold Coast. Methods Retrospective observational cohort study managed by Coast Hospital Health Service (GCHHS). Demographics, clinical data were collected. Results One hundred ninety‐seven included (mean age 45 years); 52.3% female...

10.1111/imj.15260 article EN Internal Medicine Journal 2021-05-01

Central skull base osteomyelitis (CSBO) is an incompletely defined, life-threatening infection of the bones cranial vault. We describe clinical features and outcomes CSBO in Queensland, Australia, over 11-year period.

10.1093/ofid/ofae614 article EN cc-by Open Forum Infectious Diseases 2024-09-27

Antibiotic overprescribing is a global issue that significantly contributes to increased antimicrobial resistance. Strengthening prescribing practices should be considered priority. The emergency department (ED) represents setting where antibiotics are frequently prescribed, but the determinants influence choices complex and multifaceted. We conducted an exploratory qualitative study investigate contextual factors antibiotic among clinicians in ED. employed video-reflexive ethnography (VRE)...

10.1177/10497323231198144 article EN cc-by Qualitative Health Research 2023-10-23

ABSTRACT OBJECTIVE Queensland’s Novel Coronavirus (SARS-CoV-2) suppression program has been relatively successful. Initially, it involved extensive community testing and repeat sampling of positive individuals for release from isolation. This enabled study several characteristics, including persistence detectable virus how apparent viral clearance rates varied by age sex. DESIGN We conducted an exploratory analysis Queensland Pathology SARS-CoV-2 reverse transcriptase polymerase chain...

10.1101/2020.08.27.20183483 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2020-09-01

Abstract The SARS-Coronavirus-2 pandemic disrupted normal transmission of many viral respiratory pathogens. We analysed a state-wide dataset microbiological results from public hospitals in Queensland, Australia. Following declaration the and subsequent non-pharmaceutical interventions (NPIs), we observed decreases influenza syncytial virus (RSV) consistent with other studies. However, upon easing intrastate border crowd gathering restrictions, RSV levels surged to unseasonally high levels;...

10.21203/rs.3.rs-3322878/v1 preprint EN cc-by Research Square (Research Square) 2023-09-08
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