A5060743661- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular and exercise physiology
- Cardiovascular Health and Disease Prevention
- Heart Rate Variability and Autonomic Control
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Cardiovascular Disease and Adiposity
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiovascular Effects of Exercise
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Blood Pressure and Hypertension Studies
- Gut microbiota and health
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Antimicrobial Resistance in Staphylococcus
- Diet and metabolism studies
- Herpesvirus Infections and Treatments
- Streptococcal Infections and Treatments
- Mycobacterium research and diagnosis
- Bacterial Identification and Susceptibility Testing
- Aortic Disease and Treatment Approaches
- Cardiac electrophysiology and arrhythmias
The University of Queensland
2013-2024
Sunshine Coast University Hospital
2019-2024
Griffith University
2020-2024
Middlemore Hospital
2007-2021
Counties Manukau District Health Board
2007-2021
Holland Hospital
2021
North Staffordshire Clinical Commissioning Group
2021
Baylor University Medical Center
2020
Princess Alexandra Hospital
2007-2019
The University of Notre Dame Australia
2015
Background. Enhanced influenza vaccines are needed to provide improved protection for elderly individuals. The intradermal vaccination route was hypothesized immunogenicity superior that provided by the intramuscular route.
Corynebacteria were isolated from breast tissue, pus, or deep wound swabs of 24 women; the most common species was newly described Corynebacterium kroppenstedtii, followed by amycolatum and tuberculostearicum. Gram-positive bacilli seen in samples sent for culture histological specimens 12 women, 9 women whom adequate obtained had conditions that met criteria granulomatous lobular mastitis, a chronic inflammatory disease unknown etiology.
<h3>Objective</h3> New imaging techniques have permitted the detection of subclinical LV dysfunction (LVD) in up to half patients with type 2 diabetes mellitus (DM) a normal EF. However, connection between early LVD and prognosis is unclear. This study aimed define long-term outcome associated DM. <h3>Methods</h3> In this prospective cohort study, 230 asymptomatic DM underwent measurement global longitudinal 2D strain (GLS) for were followed 10 years. All subjects had EF (≥50%) no evidence...
<h3>Importance</h3> Treatment of pediatric obesity is challenging. Preclinical studies in mice indicated that weight and metabolism can be altered by gut microbiome manipulation. <h3>Objective</h3> To assess efficacy fecal transfer (FMT) to treat adolescent improve metabolism. <h3>Design, Setting, Participants</h3> This randomized, double-masked, placebo-controlled trial (October 2017-March 2019) with a 26-week follow-up was conducted among adolescents aged 14 18 years body mass index (BMI;...
<h3>Importance</h3> High-intensity interval training (HIIT) is recognized as a potent stimulus for improving cardiorespiratory fitness (volume of oxygen consumption [VO<sub>2</sub>] peak) in patients with coronary artery disease (CAD). However, the feasibility, safety, and long-term effects HIIT this population are unclear. <h3>Objective</h3> To compare moderate-intensity continuous (MICT) adherence, efficacy VO<sub>2</sub>peak CAD. <h3>Design, Setting, Participants</h3> In single-center...
Inaccurate allergy labelling results in inappropriate antimicrobial management of the patient, which may affect clinical outcome, increase risk adverse events and costs. Inappropriate use alternative antibiotics has implications for stewardship programmes microbial resistance.All adult inpatients labelled as penicillin allergic were identified screened eligibility by study pharmacist. An accurate medication history was taken. Patients 'de-labelled', underwent oral challenge or referred to an...
Abstract Background Donor selection is an important factor influencing the engraftment and efficacy of fecal microbiota transplantation (FMT) for complex conditions associated with microbial dysbiosis. However, degree, variation, stability strain have not yet been assessed in context multiple donors. Methods We conducted a double-blinded randomized control trial FMT 87 adolescents obesity. Participants were to receive multi-donor (capsules containing four sex-matched lean donors) or placebo...
ABSTRACT Little is known about the mechanisms of transport neurotropic herpesviruses, such as herpes simplex virus (HSV), varicella-zoster virus, and pseudorabies within neurons. For these viruses, which replicate in nucleus, anterograde from cell body dorsal root ganglion (DRG) neurons to axon terminus occurs over long distances. In case HSV, unenveloped nucleocapsids human DRG cocultured with autologous skin were observed by immunoelectron microscopy colocalize conventional ubiquitous...
BackgroundPropionibacterium acnes is increasingly recognized as a cause of post-neurosurgical infection. This review patients with P . neurosurgical infection was carried out in order to determine clinical characteristics and outcomes relation duration antimicrobial treatment.
Background— The estimation of left ventricular (LV) filling pressure from the ratio transmitral and annular velocities (E/e′) after exercise echocardiography may identify diastolic dysfunction in patients who complain exertional dyspnea. This study sought to determine relative contributions E/e′ ischemia outcomes referred for echocardiography. Methods Results— Rest were obtained 522 echocardiography, followed cardiovascular death hospitalization over a median 13.2 months. Exercise >2 SD...
ABSTRACT The mechanism of anterograde transport herpes simplex virus was studied in cultured dissociated human and rat dorsal root ganglion neurons. neurons were infected with HSV-1 to examine the distribution capsid (VP5), tegument (VP16), glycoproteins (gC gB) at 2, 6, 10, 13, 17, 24 h postinfection (p.i.) or without nocodazole (a microtubule depolymerizer) brefeldin A Golgi inhibitor). Retrogradely transported VP5 detected cytoplasm cell body up nuclear membrane 2 p.i. It first de novo...
Central blood pressure (BP) and markers of wave reflection (augmentation index; AIx) measured by radial tonometry have prognostic value independent from brachial BP. The measurement the central waveform is increasingly used during altered hemodynamics, including exercise, but reliability test has not been reported under changed loading conditions. This study aimed to technique's reproducibility major hemodynamic perturbations induced exercise.Radial waveforms were recorded (SphygmoCor) in 28...
In brief: This study compared prophylactic taping and cotton wrapping with five lace-on braces to determine the best way provide ankle support. Inversion torque was applied a specially instrumented polyurethane foot form supported by tape, wrap, braces. Fresh adhesive tape provided level of However, after 350 inversion cycles, percent loss support also highest for tape. No significant difference found in amount offered two cycles.
<h3>Objectives</h3> To examine the contribution of exercise echocardiography (ExE) to diagnosis heart failure with preserved ejection fraction (HFpEF). <h3>Design</h3> Cross-sectional study patients undergoing ExE. <h3>Patients</h3> 436 fatigue or dyspnoea presenting for ExE were studied. <h3>Methods</h3> Current criteria HFpEF (evidence symptoms signs failure, EF>50%, abnormal transmitral flow and supplementary tissue Doppler measurements (E/e′) suggesting raised left ventricular filling...
We retrospectively examined medical records of 87 patients with bacteraemia caused by members the HACEK group (Haemophilus parainfluenzae, Aggregatibacter actinomycetemcomitans, aphrophilus, paraphrophilus, Cardiobacterium spp., Eikenella corrodens and Kingella spp.) to determine whether endocarditis was present, as defined Duke criteria. The overall positive predictive value (PPV) for 60 %. PPV varied different species from 0 % (E. corrodens) 100 (A. actinomycetemcomitans).
ABSTRACT Escherichia marmotae has been found in animals and the environment. Here, we isolated it from a healthy human fecal sample. The 4.91 Mb circular genome (GC content = 50.34%) is associated with three plasmids: pF12YCO47-2 (89.9 kb, 50.2% GC), pF12YCO47-3 (47.9 44.3% pF12YCO47-1 (95.4 47.2% GC).
ABSTRACT Herpes simplex virus (HSV) reactivates from latency in the neurons of dorsal root ganglia (DRG) and is subsequently transported anterogradely along axon to be shed at skin or mucosa. Although we have previously shown that only unenveloped nucleocapsids are present axons during anterograde transport, mode transport tegument proteins glycoproteins not known. We used a two-chamber culture model with human fetal DRG cultivated an inner chamber, allowing grow out penetrate agarose...