A5036014577- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Cardiovascular Disease and Adiposity
- Cardiovascular and exercise physiology
- Blood Pressure and Hypertension Studies
- Pulmonary Hypertension Research and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Hormonal Regulation and Hypertension
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Infective Endocarditis Diagnosis and Management
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiovascular Health and Disease Prevention
- Heart Rate Variability and Autonomic Control
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Hemodynamic Monitoring and Therapy
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac, Anesthesia and Surgical Outcomes
- Adipose Tissue and Metabolism
- Viral Infections and Immunology Research
Wroclaw Medical University
2016-2025
Menzies Institute for Medical Research
2015-2024
University of Tasmania
2014-2024
Baker Heart and Diabetes Institute
2016-2024
MRC University of Glasgow Centre for Virus Research
2015-2023
Hôpital Pontchaillou
2023
Uganda Virus Research Institute
2023
National University of Singapore
2022
University of Wrocław
2006-2022
The University of Sydney
2022
<h3>Objectives</h3> As myocardial fibrosis might be an important contributor to the association of obesity with left ventricular (LV) dysfunction and heart failure, we investigated effects spironolactone on LV function serological markers (procollagen type III N-terminal propeptide (PIIINP) procollagen I C-terminal (PICP)) in patients abnormal performance. <h3>Design</h3> A prospective, randomised, double-blind, placebo-controlled study. <h3>Setting</h3> university hospital. <h3>Patients...
To study the association of circulating markers fibrosis: procollagen type III amino-terminal propeptide (PIIINP), I carboxy-terminal (PIP) and collagen telopeptide (CITP): with left (LV) right ventricular (RV) longitudinal LV radial systolic function in patients heart failure course essential hypertension.The population consisted 81 hypertension divided into four groups according to NYHA classification 20 healthy controls. Cardiac was estimated by myocardial deformation indices assessed...
Apelin--a novel multifunction peptide implicated in regulation of the cardiovascular system, including blood pressure and cardiac function control - has been postulated to be involved pathophysiology hypertension hypertensive heart disease. We investigated circulating apelin level its relationship left ventricular patients with essential hypertension.We enrolled 232 without concomitant diseases affecting functions 76 healthy controls. Each patient underwent plasma measurement...
Background— Obesity predisposes to left ventricular (LV) dysfunction and heart failure; however, the risk of these complications has not been assessed in patients with a normal body mass index (BMI) but increased fat content (normal-weight obesity, NWO). We hypothesized that LV performance NWO may be impaired sought investigate potential contributors cardiac functional abnormalities. Methods Results— One hundred sixty-eight subjects (age, 38±7 years) BMI <25kg/m 2 no history any disease...
Abstract Aims Improvement in left ventricular (LV) systolic reserve, including exertional increase global longitudinal strain (GLS), may contribute to the clinical benefit from therapeutic interventions heart failure with preserved ejection fraction (HFpEF). However, GLS is an afterload-dependent parameter, and its measurements not adequately reflect myocardial contractility recruitment exercise. The estimation of work (MW) allows correction for changing afterload. We sought investigate...
Abstract Background Guidelines advocate the use of dobutamine echocardiography (DSE) in low-gradient aortic stenosis (LGAS: AVA&lt;1cm² with AVMG&lt;40mmHg) reduced left ventricular ejection fraction (LVEF &lt;50%) for determining AS severity and deciding on subsequent patient management. However, a significant proportion patients have inconclusive DSE (indeterminate AS). Purpose We aimed to assess impact management LGAS LVEF as well application transaortic flow-based criteria...
Abstract In view of the increasing prevalence aortic stenosis (AS) in ageing populations, identifying predictors favorable clinical response to transcatheter valve implantation (TAVI) is particular importance. Typically, more severe LV function impairment believed indicate less potential for improvement after eliminating cause disease. However AS, reversibility myocardial damage and its correlation with regression symptoms replacement are explored. It suggested that work (MW) indices...
Abstract Introduction Current guidelines do not specify the timing of echocardiography during acute decompensation heart failure (HF). In particular, question usefulness an echocardiographic imaging immediately before discharge from hospital, i.e. after achieving hemodynamic stabilization, remains unresolved. Aim To compare prognostic value performed on admission and in patients hospitalized due to HF decompensation, identify which markers may predict a poor early outcome discharge. Methods...
Background: Bicuspid aortic valve (BAV) is a common congenital heart defect linked to abnormal structure and dilatation. Aims: To present BAV types valvulo-aortopathy in the Polish population using latest 2021 classification. Methods: RE-BAV registry of adult ambulatory hospitalized patients with evaluated echocardiographic laboratories at 23 tertiary centers Poland (2021–2023). Results: The study included 814 — 72.7% male, average age mean (SD) 50 (17.4). Common symptoms dyspnea (54.1%)...