A5056934387- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Urinary Tract Infections Management
- Streptococcal Infections and Treatments
- Antibiotic Use and Resistance
- Antimicrobial Resistance in Staphylococcus
- Neutropenia and Cancer Infections
- Acute Myocardial Infarction Research
- Viral gastroenteritis research and epidemiology
- Nail Diseases and Treatments
- Coronary Interventions and Diagnostics
- Escherichia coli research studies
- Respiratory viral infections research
- Helicobacter pylori-related gastroenterology studies
- Infectious Diseases and Mycology
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Infective Endocarditis Diagnosis and Management
- Peripheral Artery Disease Management
- Primary Care and Health Outcomes
- Cardiac Imaging and Diagnostics
- Eosinophilic Esophagitis
- Gastrointestinal disorders and treatments
University of Wollongong
2022-2025
Westmead Hospital
2015-2024
The University of Sydney
2015-2024
Illawarra Shoalhaven Local Health District
2024
Taronga Conservation Society Australia
2016-2024
Wollongong Hospital
2023-2024
New South Wales Department of Health
2018-2022
St George Hospital
2018-2021
Bankstown Lidcombe Hospital
2014-2019
Geelong Hospital
2019
Knowledge of contemporary epidemiology candidaemia is essential. We aimed to identify changes since 2004 in incidence, species and antifungal susceptibilities Candida spp. causing Australia.These data were collected from nationwide active laboratory-based surveillance for over 1 year (within 2014-2015). Isolate identification was by MALDI-TOF MS supplemented DNA sequencing. Antifungal susceptibility testing performed using Sensititre YeastOne™.A total 527 episodes (yielding 548 isolates)...
Patients without human immunodeficiency virus (HIV) are increasingly recognized as being at risk for cryptococcosis. Knowledge of characteristics cryptococcosis in these patients remains incomplete.We conducted a retrospective study 46 Australian and New Zealand hospitals to compare its frequency with HIV describe HIV. between January 2015 December 2019 were included.Of 475 cryptococcosis, 90% (426 475) marked predominance both Cryptococcus neoformans (88.7%) gattii cases (94.3%). Most...
Important culture-change initiatives (e.g. improving hand hygiene compliance) are frequently associated with variable uptake among different healthcare worker (HCW) categories. Inherent personality differences between these groups may explain change and help improve future intervention design.We used an innovative personality-profiling tool (ColourGrid®) to assess standard HCW categories at five large Australian hospitals using two data sources (HCW participant surveys [PS] generic...
Candidaemia is associated with high mortality. Variables mortality have been published previously, but not developed into a risk predictive model for We sought to describe the current epidemiology of candidaemia in Australia, analyse predictors 30-day all-cause mortality, and develop validate model.Adults were studied prospectively over 12 months at eight institutions. Clinical laboratory variables time blood culture-positivity subject multivariate analysis association A score was examined...
Patients with haematological malignancies, haemopoietic stem cell transplant recipients and patients requiring admission to intensive care settings are at high risk for invasive candidiasis (IC). Over the past decade, there has been increased reporting of non-albicans species fluconazole resistance in Australia. These guidelines provide updated evidence-based recommendations diagnosis management IC adult paediatric haematology, oncology settings. Optimal pharmacological non-pharmacological...
Background/Objectives: Antimicrobial resistance (AMR) is a global problem with antibiotic consumption considered key modifiable factor for the development of AMR. Long-term care (LTC) facilities have been identified as potential reservoirs Escherichia coli (E. coli) due to high rates urinary tract infection (UTI) and levels among residents. However, while relationship between these two factors well accepted, little known about possible temporal these. This study explores trends in E. LTC...
Background: Antimicrobial resistance (AMR) is a global health challenge with significant variation. Little known about the prevalence on smaller geographical scale. Objectives: This study aimed to explore geo-temporal variation in antibiotic Escherichia coli (E. coli) urinary isolates Illawarra Shoalhaven region, region south of Sydney. Methods: Data from urine E. people living community were geospatially analysed 2008 2018. The proportion resistant was mapped by type (amoxicillin clavulanic...
Candidaemia carries a mortality of up to 40% and may be related increasing complexity medical care. Here, we determined risk factors for the development candidaemia.We conducted prospective, multi-centre, case-control study over 12 months. Cases were aged ≥18 years with at least one blood culture positive Candida spp. Each case was matched two controls, by age within 10 years, admission 6 months, admitting unit, duration as long time between onset candidaemia.A total 118 incident cases 236...
Resistance to azoles in Candida tropicalis is increasing and may be mediated by genetic characteristics. Using whole genome sequencing (WGS), we examined the diversity of 82 bloodstream C. isolates from two countries one ATCC strain a global context. Multilocus sequence typing (MLST) single nucleotide polymorphism (SNP)-based phylogenies were generated. Minimum inhibitory concentrations (MIC) for antifungal agents determined using Sensititre YeastOne YO10. Eleven (13.2%)...
Listeria monocytogenes causes gastroenteritis, meningitis and bacteraemia in immunocompromised, pregnant patients, the elderly as well immunocompetent patients. Focal infections with this organism are uncommon, especially sporadic (non-outbreak) setting, require high index of suspicion challenging to diagnose. We present 3 cases presenting focal our hospitals, all which first reported from Australia. Three unrelated unique caused by presented. 1) A 73 year old Caucasian lady on...
Abstract Background Although treatment of mild peri‐prosthetic infection in implant‐based breast reconstruction results high rates resolution, successful management severe remains a significant challenge. Methods In this case series, protocol utilizing novel dressing – negative pressure wound therapy with instillation ( NPWTi ) for the patients is described. This an operative technique involving: (i) explantation prosthesis and application to implant pocket; (ii) change dressing; (iii)...
Abstract We describe the successful management of Anncaliia algerae microsporidial myositis in a man with graft versus host disease after hemopoietic stem cell transplantation. also summarize clinical presentation and approaches discuss importance research into acquisition this infection strategies for prevention.