- Environmental Toxicology and Ecotoxicology
- Toxic Organic Pollutants Impact
- Mycotoxins in Agriculture and Food
- Reproductive biology and impacts on aquatic species
- Microplastics and Plastic Pollution
- Pharmaceutical and Antibiotic Environmental Impacts
- Marine Biology and Environmental Chemistry
- Aquaculture Nutrition and Growth
- Effects and risks of endocrine disrupting chemicals
- Plant and fungal interactions
- Carcinogens and Genotoxicity Assessment
- Fish Ecology and Management Studies
- Microbial infections and disease research
- Metabolomics and Mass Spectrometry Studies
- Oil Spill Detection and Mitigation
- Isotope Analysis in Ecology
- Ruminant Nutrition and Digestive Physiology
- Pesticide and Herbicide Environmental Studies
- Wheat and Barley Genetics and Pathology
- Milk Quality and Mastitis in Dairy Cows
- Veterinary medicine and infectious diseases
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Aquaculture disease management and microbiota
- Marine Ecology and Invasive Species
- Microbial bioremediation and biosurfactants
Kagoshima University
2015-2025
Mitsubishi Chemical (Germany)
2003
Mitsubishi Chemical (Japan)
2003
Mitsubishi Group (Japan)
2003
Tokyo University of Marine Science and Technology
1997
National Institute for Environmental Studies
1997
Histopathological alterations in gill, liver and kidney of common carp, Cyprinus carpio, intoxicated with sub-lethal concentrations chlorpyrifos (O,O,-diethyl-O-3,5,6-trichloro-2-pyridyl phosphorothioate) pesticide (1 100 μg/L) for a period 14 days were analyzed under light microscope. Gill exhibited hyperplasia hypertrophy gill epithelium, blood congestion, dilation marginal channel, epithelial lifting, lamellar fusion, disorganization, aneurysm, rupture the pillar cells necrosis....
Polycyclic aromatic hydrocarbons (PAHs) are known to induce developmental malformations in fish embryos. However, the interaction between aryl hydrocarbon receptor (AhR) and cytochrome P450 (CYP) PAH-induced development defects remains unclear. Therefore, we investigated effects of CYP1A inhibitor piperonylbutoxide (PBO) AhR antagonist CH223191 (CH) on Japanese medaka (Oryzias Latipes) embryos exposed different PAHs. were three conditions: PAH alone, PBO, CH. Microscopic observations...
Abstract Using a 1 H NMR metabolomics approach, the effects of dietary exposure bunker A heavy oil (0.01, 0.1, 1, and 5% in diet) on freshwater carp, Cyprinus carpio , were examined. Statistical analysis by PCA score plots showed that amount metabolites groups differed from those control group. Although no discernible noted 0.1% group as well lowest concentration (0.01%) group, several such amino acid (e.g., leucine, isoleucine, valine, glutamine, histidine, proline, methionine), 3‐ D...
We examined the effectiveness of cocopeat and rice hull powder obtained from agricultural wastes as biocarriers for an oil-degrading bacterial consortium. Scanning electron microscopy revealed colonization strong attachment cells on surface both carriers. Results a 60-day in vitro seawater bioremediation trial showed significant oil reduction high cultivable counts treatments augmented with carrier-attached consortia compared to supplemented same consortium free living encapsulated forms....
The aims of the present study were to investigate efficacy measuring bovine urinary zearalenone (ZEN) concentrations by using a commercially available ELISA method in cattle kept under different feeding conditions monitor natural contamination feeds at farm level, and effects supplementation mycotoxin adsorbent (MA) product feed based on ZEN concentration. First, Japanese Black herds for breeding (4 herds) fattening purposes provided with similar conditions. Then, samples from 5 cows each...
Abstract Japanese flounder ( Paralichthys olivaceus ), red sea bream Pagrus major and Java medaka Oryzias javanicus ) were exposed to water borne polycyclic aromatic hydrocarbons (PAHs) for 10 days compare PAH bioconcentration P450 enzyme induction by ethoxyresorufin‐ O ‐deethylase (EROD) activity use in oil spill biomonitoring Asian waters. Target exposure concentration phenanthrene, pyrene, chrysene 30 μg/L each, while benzo[ a ]pyrene was 3.0 μg/L. Phenanthrene pyrene accumulated the...
Abstract Java medaka ( Oryzias javanicus ), which is distributed in estuarine waters of East to Southeast Asia, proposed here for consideration as a new marine test fish. Semi‐static acute toxicity tests were conducted at 26°C 1 week, 2 weeks, and month old Java‐medaka exposed 4‐chlorophenol zinc, weeks olds potassium dichromate (hexavalent chromium) sodium hypochlorite (residue chlorine). Ninety‐six hours LC50s 4‐chlorophenol, hexavalent chromium, residue chlorine from 3.0 4.1, 12.4 14.7,...
ABSTRACT This study investigated the effects of waterborne chlorpyrifos with concentrations 1 and 100 µg/L for L H‐groups, respectively, on metabolome profiles carp plasma using H‐NMR. Principal component analysis suggests that exposure firstly affected in H‐groups day 2 or 4, followed a second effect both groups 14. Levels metabolites related to energy production body, such as glucose, glycerol, valine, leucine, isoleucine, lactate, alanine, 3‐D‐hydroxybutyrates acetoacetate, significantly...
Zearalenone (ZEN) and its metabolites are important nonsteroidal estrogenic mycotoxins that cause reproductive disorders in domestic animals, especially pigs. We aimed to simultaneously detect ZEN á-zearalenol (α-ZOL) β-zearalenol (β-ZOL) porcine follicular fluid (FF) by liquid chromatography-tandem mass spectrometry. α-ZOL, but not β-ZOL, were detected all pooled FF samples collected from coexisting follicles (diameter ≥ 6 mm) within 10 ovaries. Furthermore, α-ZOL pretreated with...
Heavy oil (HO) pollution is one of the most important environmental issues globally. However, little known about immunotoxicity HO in fish. We therefore investigated effects exposure on immunocompetence and expression immune-related genes Japanese flounder, Paralichthys olivaceus. To test immunocompetency, serum collected from fish was mixed with Edwardsiella tarda, plated, resultant numbers bacterial colonies were counted. Plates HO-exposed (5 d postexposure [dpe]) had significantly higher...