Margherita Serra

ORCID: 0000-0003-0914-9605
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About
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Research Areas
  • Breast Cancer Treatment Studies
  • Breast Lesions and Carcinomas
  • COVID-19 and healthcare impacts
  • Breast Implant and Reconstruction
  • Total Knee Arthroplasty Outcomes
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cancer and Skin Lesions
  • Knee injuries and reconstruction techniques
  • Trauma and Emergency Care Studies
  • Global Cancer Incidence and Screening
  • Lower Extremity Biomechanics and Pathologies
  • Cancer-related Molecular Pathways
  • Shoulder Injury and Treatment
  • Advanced Breast Cancer Therapies
  • Ancient Mediterranean Archaeology and History
  • Advances in Oncology and Radiotherapy
  • Cancer Treatment and Pharmacology
  • Enhanced Recovery After Surgery
  • HER2/EGFR in Cancer Research
  • Cancer survivorship and care
  • Cancer therapeutics and mechanisms
  • Diabetic Foot Ulcer Assessment and Management
  • Cancer Diagnosis and Treatment
  • Radiation Dose and Imaging
  • Economic and Financial Impacts of Cancer

Istituto Ortopedico Rizzoli
2015-2025

Policlinico S.Orsola-Malpighi
2009-2024

Istituti di Ricovero e Cura a Carattere Scientifico
2022-2024

Azienda USL di Bologna
2023-2024

University of Bologna
2016-2022

University of Birmingham
2020-2022

Institut de Virologie
2020-2021

NIHR Birmingham Biomedical Research Centre
2021

Yorkshire Cancer Research
2021

Urology Foundation
2021

Abstract RNA modifications are key regulatory factors for several biological and pathological processes. They abundantly represented on ribosomal (rRNA), where they contribute to regulate function in mRNA translation. Altered modification pathways have been linked tumorigenesis as well other human diseases. In this study we quantitatively evaluated the site-specific pseudouridylation pattern rRNA breast cancer samples exploiting RBS-Seq technique involving bisulfite treatment coupled with a...

10.1093/narcan/zcad026 article EN cc-by NAR Cancer 2023-03-11

In recent years, lateral extra-articular tenodesis (LET) has been shown to be promising in reducing the graft failure rate at short-term follow-up. However, there is a lack of studies investigating incidence complications and osteoarthritis (OA) after this procedure, only few have reported long-term results anterior cruciate ligament (ACL) reconstruction. This study aimed compare rate, clinical outcomes, OA 3 different ACL reconstruction techniques: single-bundle quadrupled hamstring tendon...

10.1177/23259671241302348 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2025-01-01

A 74-year-old female patient presented with a hard breast mass and dimpling clinical suspicion of carcinoma. Histological evaluation revealed granular cell tumour. Granular tumour is rare neoplasm, mostly benign in origin that may arise every body site, 5%-15% cases occur the breast. It strongly suggested tumours Schwann cells. Clinically, presentation mimic mammary carcinoma their similar features on mammography ultrasound make it difficult to differentiate between them.

10.1177/2050313x19841154 article EN cc-by-nc SAGE Open Medical Case Reports 2019-01-01

In Brief Objective: The goal of our study was to evaluate the sensitivity and specificity sentinel lymph node biopsy (SLNB) frozen section (FS) examinations detect metastatic nodes also its potential role in avoiding unnecessary demolitive axillary surgery. Background: SLNB is standard care surgical oncology breast. Intraoperative evaluation SLN seems achieve sufficient for macrometastasis (Ma), leading dissection (ALND) only when strictly necessary. Is it equally as clear perform ALND if...

10.1097/sla.0b013e31824def4e article EN Annals of Surgery 2012-03-13

Abstract Purpose The purpose of the study was to investigate outcome dual-mobility cup (DM) compared with a standard (SC) in primary total hip arthroplasty (THA) long-term follow-up based on regional Italian joint registry (RIPO). Methods Registry Prosthetic Orthopaedic Implant (RIPO) consulted, looking for all THAs implanted from 2000 2019. Three thousand seven hundred ten were arthroplasties and 85.816 THAs, 89.526 THA. Demographics, survival rates causes revision evaluated between two...

10.1007/s00264-022-05639-z article EN cc-by International Orthopaedics 2022-11-30

Objectives: Modern lateral extra-articular tenodesis (LET) has shown promising results at short term follow-up but there is a lack of studies investigating the incidence complication and osteoarthritis (OA) long-term. The aim study was to compare in terms failure rates, clinical outcomes OA three different ACL reconstruction techniques including hamstring single-bundle (HS group), patellar tendon (BTB) over-the-top with LET (LET group). Methods: Seventy-five patients were randomized receive...

10.1177/2325967124s00279 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2024-07-01

Pseudoangiomatous stromal hyperplasia (PASH) is a benign breast condition commonly presented as an incidental microscopic finding. However, it can also manifest mass-forming lesion (tumorous PASH) or gigantomastia (diffuse PASH). Most of the previously reported cases are unilateral tumorous PASH treated by mastectomy. In this article, we rare case diffuse bilateral PASH. A 21-year-old woman with two-year history enlargement and neck pain. Physical examination revealed asymmetrical...

10.3233/bd-190428 article EN Breast Disease 2020-04-07

Aim of the studyProving on basis scientific evidence derived from a long lasting experience in breast surgery field, how pathologic nipple discharge, as single symptom, can hide more often elderly women malignancies galactophorous ducts.

10.1186/1471-2318-9-s1-a21 article EN cc-by BMC Geriatrics 2009-04-01

Objective: Identification of clinical and biological characteristics breast cancer in women with mammary Paget's disease (MPD).Methods: We performed a retrospective analysis for 36 primary diagnosis disease, patients were treated Sant' Orsola-Malpighi Breast Unit Italy, between 2000 2016.Patients demographics, data, radiologic pathologic reports extracted from electronic health records.Result: cases MPD involved.The mean age was 64.28 years (Range, 36-86 years).Only 14 (38.9%) found to have...

10.21614/sgo-25-5-236 article EN Surgery Gastroenterology and Oncology 2020-01-01
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