Objective: To determine the efficacy of a three-month resistance training programme on mobility, muscle strength and lean body mass patients with pancreatic cancer-induced cachexia. Design: Randomized controlled trial. Setting: Elsahel Teaching Hospital, outpatient clinic Faculty Physical Therapy, Cairo, Egypt. Participants: Patients Interventions: Participants were randomized to group ( n = 20) control 20). Main measures: Outcomes including measured at baseline, three months after surgical...

The aim of the present study was to assess short-term effects Thymoquinone (TQ) on oxidative stress, glycaemic control, and renal functions in diabetic rats. DM induced groups II III with a single dose streptozotocin (STZ), while group I received no medication (control). rats were then given distilled water, TQ at 50 mg/kg body weight/day for 4 weeks. Lipid peroxidase, nitric oxide (NO), total antioxidant capacity (TAC), glycated haemoglobin (HbA1c), lipid profiles, function assessed....

The reduction in estrogen levels results a decrease bone density at menopause. Irisin is myokine that modulates the benefits of exercise, which may include health. This study was planned to examine irisin’s impact preventing osteoporosis after ovariectomy. 4 groups female albino rats (10 rats/group): control, sham-operated, ovariectomized (OVX-control), and OVX-irisin-treated. Serum markers [osteocalcin (OC), alkaline phosphatase (BALP), tartrate-resistant acid (TRAP), calcium (Ca++),...

Abstract Despite the extensive use of cisplatin (CP) as a chemotherapeutic agent, its clinical is often restricted by undesirable side effects, such toxicity to normal tissues. The aim this study was probe effect combinatorial treatment low multiple doses antioxidants on CP‐induced and mitochondrial apoptotic pathway in hepatocytes. Animals received single toxic dose CP (7.5 mg/kg body weight) with or without combined epigallocatechin gallate (EGCG) coenzyme Q10 (CoQ10) (15 5 weight,...

To investigate the efficacy of extracorporeal shockwave therapy (ESWT) on cervical myofascial pain following neck dissection in reducing and improving range motion (ROM).Forty-six patients with surgery were recruited subdivided at random into two equal groups. The ESWT group received once a week for 4 weeks (0.25 mL/mm2, 1,000 shocks) topical non-steroidal anti-inflammatory drug (3 times/day weeks). control only NSAID. assessment was done by using visual analog scale (VAS) pressure...

Doxorubicin (DXR) is commonly used as a drug for cancer treatment. However, there have been reports of neurotoxicity associated with chemotherapy. Galantamine (GLN) medication that inhibits cholinesterase activity, providing relief from the neurotoxic effects seen in individuals Alzheimer's disease. This study explored potential ameliorative effect GLN on brain induced by DXR.

Objective: To examine the impact of telerehabilitation training on exercise capacity, lung function, and health-related quality life (HRQOL) in comparison to no rehabilitation for post-COVID-19 symptoms adult females.Methods: A randomized controlled trial 48 females after mild moderate COVID-19 survival were equally randomly assigned one two groups: intervention group or control group. Three sessions per week 6 weeks a program provided via smartphone Spirometry was used quantify 6-minute...

Background: Gentamicin (GM) is an antibiotic that widely used to treat many Gram-negative bacteria, such as those involved in urinary tract infections. However, being nephrotoxic, GM dose adjustment and reno-protective elements must be concurrently administered with minimize kidney damage. Oxidative stress plays a pivotal role the pathogenesis of GM-induced nephrotoxicity. Thymoquinone (TQ) promising therapeutic substance, extensively studied diseases, diabetes mellitus, cancer,...

Background: Oxidative stress, lipid profile and renal functions are well-known conventional risk factors for diabetes mellitus (DM). Metformin gliclazide popularly used monotherapy drugs the treatment of DM. Aims: This study aims to assess short-term single dual therapy glipizide/metformin on oxidative glycemic control, serum profiles function in diabetic rats. Methods: DM was induced rats with streptozotocin (STZ), then five different treatments were applied, including group I (untreated...

SARS-CoV-2, an epidemic, causes severe stress in both human and animals may induce oxidative (OS) increases susceptibility to infection. Domestic are found infected by their COVID-2 suffering owners. Chronic immobilization (CIS), a model of psychological physical confinement, can trigger depression anxiety animals. We evaluated the ameliorative effect proposed SARS-CoV-2 prophylactic drugs melatonin, vitamin C, zinc on CIS-induced OS, inflammation, DNA damage rats. Forty male Swiss albino...

The long-term consequences of congenital diaphragmatic hernia (CDH), which include altered lung functions and compromised cardiopulmonary capacity, impact functional performance quality life. This study investigates the effects virtual reality-based exercise programs on pulmonary functions, performance, life in children with repaired CDH.A randomized controlled clinical trial was performed. Fifty-two CDH (aged 6-10 years) were enrolled randomly allocated to exercises plus traditional...

Aim. To investigate the efficacy of gabapentin phonophoresis for neuropathic pain management in intercostobrachial neuralgia cases. Material and methods. Fifty-seven females with were randomly collected then allocated into two groups, Study group (gabapentin phonophoresis) Control gel). group: received 4 times/week weeks (a total 16 sessions) using continuous ultrasound (1 MHz, 1.5 W/cm², 5 minutes). topical 6% w/w gel three times per day on affected site. The methods assessment included...

Physiological and biochemical changes during normal pregnancy may precipitate a state of insulin resistance (IR) without disrupting the body's physiology. The present study aimed to investigate association between indices sensitivity blood pressure among normotensive euglycemic pregnant women. cross‑sectional was conducted February December, 2021. It comprised 133 women who were non‑diabetic had pressure. oral glucose tolerance test fasting levels assessed, β‑cell function computed 24th 28th...

Abstract Background and Purpose: To examine the respiratory functional benefits of manual diaphragmatic release for Cleaning‐Laborers Exposed to Occupational Hazards. Methods A randomized controlled trial 36 participants aged 35–45 years was randomly allocated into two groups. The experimental group (n = 18); received diaphragm along with training exercises, control exercises only. Three times/week 12 consecutive weeks. serum immunoglobulin E level, pulmonary functions [forced expiratory...

The risk of cardiovascular disease (CVD) in patients with chronic kidney (CKD) is estimated to be far greater than that the general population. Adropin regulates endothelial function and may play a role pathogenesis CVD. Angiotensin-converting enzyme inhibitor (ACEI) treatment was reported have protective effect on both renal function. This study investigated whether adropin associated outcomes after using ACEI CKD rats. In 2021, Zagazig, Egypt, rats were assigned to: GI, control group...

Blood transfusion is a conventional therapeutic procedure; however, the perceptions of general public and healthcare professionals (HCPs), especially physicians nurses, remain unclear, although insights HSPs may affect treatment decision. This study aimed to assess awareness HCPs about blood risks consent in Qassim region Saudi Arabia, uncover factors that influence such perceptions.This used two different closed questionnaires were distributed electronically between February March 2018...

Aspirin resistance is described as the failure of aspirin to decrease production thromboxane A2 by platelets, which mechanism decreases platelet activation and aggregation. This study was performed assess prevalence among cardiovascular patients in al-Qassim, Saudi Arabia.The used a survey with first recurrent attacks ischemic heart disease (IHD) available data from blood samples processed using VerifyNow® kit, measures reaction units (ARUs).A total 119 were included: 45 their IHD episodes...

Background: Cardiorespiratory fitness is expressed by maximal oxygen consumption (VO2max) which measures (O2) capacity of an individual performing 6 minutes treadmill exercise test. In this study, the cardiopulmonary among female healthy University students in Al-Qassim University, Saudi Arabia was assessed, along with its association body mass index (BMI), blood pressure, and fat percentage. Methods: cross-sectional a self-administered questionnaire distributed. Heart rate, weight, height,...