A5084888798- Law and Political Science
- European and International Law Studies
- SARS-CoV-2 and COVID-19 Research
- European Union Policy and Governance
- Nosocomial Infections in ICU
- Robotics and Sensor-Based Localization
- Pneumonia and Respiratory Infections
- COVID-19 epidemiological studies
- 3D Surveying and Cultural Heritage
- Viral Infections and Immunology Research
- Virology and Viral Diseases
- International Law and Human Rights
- Viral gastroenteritis research and epidemiology
- Body Contouring and Surgery
- International Relations and Autism
- Vaccine Coverage and Hesitancy
- Inflammatory Myopathies and Dermatomyositis
- Minority Rights and Languages
- Microscopic Colitis
- SARS-CoV-2 detection and testing
- Polish Legal and Social Issues
- Sarcoidosis and Beryllium Toxicity Research
- German legal, social, and political studies
- Gallbladder and Bile Duct Disorders
- Animal Virus Infections Studies
Jacksonville University
2024
University of Florida
2024
University Hospital of Basel
2019-2023
University of Basel
2020-2023
Systems, Applications & Products in Data Processing (Germany)
2019
University of Miami
2017
Universität der Bundeswehr München
2010
Klinikum Hanau
1997-2001
Virginia Commonwealth University Medical Center
2001
Mount Sinai Hospital
1998
To determine the risks and benefits of gastric bypass-induced weight loss on severe venous stasis disease in morbid obesity.Severe obesity is associated with a risk lower extremity disease, pretibial ulceration, cellulitis, bronze edema.The GBP database was queried for including ulcers, edema, cellulitis.Of 1,976 patients undergoing GBP, 64 (45% female) met criteria. Mean age 44 +/- 10 years. Thirty-seven had 4 23 both, 17 recurrent cellulitis. All 2 to 4+ pitting edema. preoperative body...
Abstract Objectives SARS-CoV-2 may cause acute lung injury, and secondary infections are thus relevant complications in patients with COVID-19 pneumonia. However, detailed information on community- hospital-acquired among pneumonia is scarce. Methods We identified 220 SARS-CoV-2-positive hospitalized at the University Hospital Basel, Switzerland (between 25 February 31 May 2020). excluded who declined general consent ( n = 12), without clinical evidence of 29), for < 24 h 17). evaluated...
The first case of SARS-CoV-2 in Basel, Switzerland was detected on February 26 th 2020. We present a phylogenetic study to explore viral introduction and evolution during the exponential early phase local COVID-19 outbreak from until March 23 rd . sequenced naso-oropharyngeal swabs 746 positive tests that were performed at University Hospital Basel period. successfully generated 468 high quality genomes unique patients called variants with our Pipeline (COVGAP), analysed genetic diversity...
A variety of antiviral treatments for COVID-19 have been investigated, involving many repurposed drugs. Currently, the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp, encoded by nsp12-nsp7-nsp8) has targeted numerous inhibitors, e.g., remdesivir, only provisionally approved treatment to-date, although clinical impact these interventions remains inconclusive. However, potential emergence resistance poses a threat to efficacy any successful therapies on wide scale. Here, we propose framework...
Abstract Purpose Panel PCR tests provide rapid pathogen identification. However, their diagnostic performance is unclear. We assessed the of Biofire © FilmArray pneumonia (PN)-panel against standard culture in broncho-alveolar lavage (BAL) samples. Methods Setting: University Hospital Basel (February 2019 to July 2020), including hospitalized patients with a BAL (± pneumonia). determined sensitivity and specificity PN-panel culture. Using univariate logistic regression, we calculated odds...
Abstract Transmission chains within small urban areas (accommodating ∼30 per cent of the European population) greatly contribute to case burden and economic impact during ongoing coronavirus pandemic should be a focus for preventive measures achieve containment. Here, at very high spatio-temporal resolution, we analysed determinants severe acute respiratory syndrome 2 (SARS-CoV-2) transmission in area, Basel-City (Switzerland). We combined detailed epidemiological, intra-city mobility...
Background Transmission chains within small urban areas (accommodating∼30% of the European population) greatly contribute to case burden and economic impact during ongoing COVID-19 pandemic, should be a focus for preventive measures achieve containment. Here, at very high spatio-temporal resolution, we analysed determinants SARS-CoV-2 transmission in area, Basel-City (Switzerland). Methodology. We combined detailed epidemiological, intra-city mobility, socioeconomic data-sets with...
Infestations with scabies mites are a global burden affecting individuals of all ages, classes and ethnicities. As poor sanitation overcrowding favor the transmission this highly contagious disease, epidemic outbreaks frequently observed among displaced persons asylum seekers. Due to growing influx refugees during last years, public health authorities in host countries confronted challenge treat diagnosed or suspected promptly effectively avoid further spreading infestation. This study aimed...
During COVID19 pandemic, SARS-CoV-2 rapid antigen tests (RATs) were marketed with minimal or no performance data. We aimed at closing this gap by determining technical sensitivities and specificities of 30 RATs prior to market release. developed a standardized validation protocol assessed across four diagnostic laboratories. tested in parallel using the Standard Q® (SD Biosensor/Roche) assay as internal reference. used left-over universal transport/optimum media from nasopharyngeal swabs 200...
Abstract Background The first case of SARS-CoV-2 in Basel, Switzerland, was detected on February 26 th 2020. We present a phylogenetic longitudinal study and explore viral introduction evolution during the exponential early phase local COVID-19 outbreak from until March 23 rd . Methods sequenced naso-oropharyngeal swabs, generated 468 high quality genomes, called variants with our Pipeline (COVGAP). analysed genetic diversity using PANGOLIN taxonomic lineages. To identify dissemination...
Abstract Antiviral treatments for COVID-19 have involved many repurposed drugs. Currently, SARS-CoV-2 RNA-dependent RNA polymerase (RdRp, encoded by nsp12-nsp7-nsp8 ) has been targeted numerous inhibitors with debated clinical impact. Among these, remdesivir conditionally approved the treatment of patients. Although emergence antiviral resistance, an indirect proxy efficacy, poses a considerable healthcare threat, evolutionary perspective on emerging resistant mutants is still lacking. Here...
The industrial market for processing large-scale films has seen dramatic changes since the 1980s and almost completely been replaced by lasers digital processes. A commonly used technology engraving screens, print embossing forms in printing industry, well known then, is use of RF-excited CO<sub>2</sub> with a beam power up to about 1 kW, modulated accordance pattern be engraved. Future needs high-security (banknotes, security papers, passports, etc.) will require laser at least half million...
We aim to investigate the contribution of interstitial lung disease (ILD) mortality in patients with inflammatory bowel (IBD).
<b>Introduction:</b> An excess of malignancy following sarcoidosis has been reported previously. However, the association cancer is barely reported. <b>Aim:</b> We aim to perform a case series subjects presenting with occurring malignancy, particularly breast cancer. <b>Methods:</b> In cross-sectional study, we enrolled all confirmed diagnosis registered in University Miami Sarcoidosis Program registry from Jan. 2016 2017. was defined per World Association for and other Granulomatous...