Hai Lu

ORCID: 0000-0003-0937-954X
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About
Contact & Profiles
Research Areas
  • Plant Molecular Biology Research
  • Plant Reproductive Biology
  • Plant Stress Responses and Tolerance
  • Photosynthetic Processes and Mechanisms
  • Telomeres, Telomerase, and Senescence
  • Plant Gene Expression Analysis
  • Chromosomal and Genetic Variations
  • Plant tissue culture and regeneration
  • Biochemical and biochemical processes
  • Plant nutrient uptake and metabolism
  • Plant biochemistry and biosynthesis
  • Apelin-related biomedical research
  • Hibiscus Plant Research Studies
  • Ginkgo biloba and Cashew Applications
  • CRISPR and Genetic Engineering
  • Seed Germination and Physiology
  • Legume Nitrogen Fixing Symbiosis
  • Aluminum toxicity and tolerance in plants and animals
  • Analytical chemistry methods development
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Enzyme-mediated dye degradation
  • Plant Diversity and Evolution
  • Plant Parasitism and Resistance
  • Pesticide Residue Analysis and Safety
  • Mitochondrial Function and Pathology

Beijing Forestry University
2014-2025

Jining Medical University
2010-2024

Fudan University
2024

State Key Laboratory of Medical Neurobiology
2024

Guangxi University
2019-2023

Guangxi Subtropical Crops Research Institute
2020

Tianjin University of Traditional Chinese Medicine
2020

Shanghai Medical College of Fudan University
2016

University of Florida
2010-2015

University of Minnesota
2005-2014

Tapetal programmed cell death (PCD) is a prerequisite for pollen grain development in angiosperms, and cysteine proteases are the most ubiquitous hydrolases involved plant PCD. We identified papain-like protease, CEP1, which tapetal PCD Arabidopsis thaliana. CEP1 expressed specifically tapetum from stages 5 to 11 of anther development. The protein first appears as proenzyme precursor protease vesicles then transported vacuole transformed into mature enzyme before rupture vacuole. cep1...

10.1105/tpc.114.127282 article EN The Plant Cell 2014-07-01

In plants, mounting an effective innate immune strategy against microbial pathogens involves triggering local cell death within infected cells as well boosting the immunity of uninfected neighboring and systemically located cells. Although not much is known about this, it evident that well-coordinated cell–cell signaling critical in this process to confine infection tissue while allowing for spread systemic signals throughout whole plant. support notion, direct cell-to-cell communication was...

10.1105/tpc.113.110676 article EN The Plant Cell 2013-06-01

The mtlD gene encoding mannitol-1-phosphate dehydrogenase, which catalyzes the biosynthesis of mannitol from fructose, was cloned Escherichia coli and transferred to poplar (Populus tomentosa Carr.) through Agrobacterium-mediated transformation. transgenic plants were screened selected on Murashige Skoog (MS) medium containing 30–50 mg l−1 kanamycin verified by polymerase chain reaction (PCR) Southern blotting. Expression led synthesis accumulation in plants. Gas chromatography mass...

10.1093/treephys/25.10.1273 article EN Tree Physiology 2005-10-01

Tapetal programmed cell death (PCD) is a complex biological process that plays an important role in pollen formation and reproduction. Here, we identified the MYB2 transcription factor expressed tapetum from stage 5 to 11 was essential for tapetal PCD development Arabidopsis thaliana. Downregulation of retarded degeneration, produced defective pollen, decreased vitality. EMSA transcriptional activation analysis revealed acted as upstream activator directly regulated expression proteases CEP1...

10.3390/ijms23073563 article EN International Journal of Molecular Sciences 2022-03-24

Both tracheary elements and fiber cells undergo programmed cell death (PCD) during xylem development. In this study we investigated the role of papain-like cysteine protease CEP1 in PCD Arabidopsis. was located wall cells, expression levels inflorescence stems increased stem maturation. cep1 mutant plants exhibited delayed growth reduced number compared to wild-type plants. Transmission electron microscopy demonstrated that organelle degradation PCD, thicker secondary walls were present...

10.1093/jxb/ery356 article EN cc-by Journal of Experimental Botany 2018-10-26

Chloroplasts are the most major producers of reactive oxygen species (ROS) during photosynthesis. However, function thylakoid ascorbate peroxidase (tAPX) in response to oxidative stress wood trees is largely unknown. Our results showed that PtotAPX Populus tomentosa could effectively utilize ascorbic acid (AsA) hydrolyze hydrogen peroxide (H2O2) vitro. The overexpression or antisense (OX-PtotAPX anti-PtotAPX, respectively) plants did not significantly affect plant morphology growth. When...

10.3390/ijms23063340 article EN International Journal of Molecular Sciences 2022-03-19

Elymus nutans Griseb. (Poaceae: Triticeae, 2n=6x=42) is a dominant perennial plant species in the Qinghai-Tibetan Plateau China, which an important forage resource high-altitude and cold regions most popular used for high yield artificial grassland planting because of its rich nutritional value good palatability herbivorous ruminant animals. In this study, using advanced sequencing technology, we generated allohexaploid reference genome E. nutans, representing three sets chromosomes...

10.1101/2025.03.29.645954 preprint EN cc-by-nc-nd 2025-03-31

Abstract Vacuolar processing enzyme (VPE) is responsible for the maturation and activation of vacuolar proteins in plants. We found that βVPE was involved tapetal degradation pollen development by transforming proproteases into mature protease Arabidopsis thaliana. expressed specifically tapetum from stages 5 to 8 anther development. The protein first appeared as a proenzyme transformed before 7–8. recombinant self-cleaved 27 kDa at pH 5.2. could induce CEP1 vitro. βvpe mutants exhibited...

10.1093/jxb/erz560 article EN cc-by Journal of Experimental Botany 2019-12-18

Alzheimer's disease (AD), the leading cause of age-related dementia, is characterized by abnormal β-amyloid accumulation. During learning, memory formation and consolidation, increased levels histone H3 H4 acetylation are observed. The present study reported significantly decreased level H4K16ac in plasma patients with AD compared healthy subjects via western blotting reverse transcription-quantitative (RT-q)PCR. Lysine acetyltransferase 8 (KAT8) expression, major lysine responsible for...

10.3892/etm.2020.9216 article EN Experimental and Therapeutic Medicine 2020-09-11
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