A5102768627- Mitochondrial Function and Pathology
- Cancer, Hypoxia, and Metabolism
- Ion Channels and Receptors
- Electrospun Nanofibers in Biomedical Applications
- Cancer-related Molecular Pathways
- Magnesium in Health and Disease
- Tissue Engineering and Regenerative Medicine
- Planarian Biology and Electrostimulation
- Sodium Intake and Health
- RNA modifications and cancer
- 3D Printing in Biomedical Research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
The Affiliated Yongchuan Hospital of Chongqing Medical University
2015-2022
Chongqing Medical University
2015-2022
Abstract Our previous study suggested that microtubule network alteration affects the process of glycolysis in cardiomyocytes (CMs) via regulation hypoxia-inducible factor (HIF)-1α during early stages hypoxia. However, little is known regarding underlying mechanisms alteration-induced changes HIF-1α. The von Hippel–Lindau tumor suppressor protein (pVHL) has been shown to mediate ubiquitination HIF-1α nuclear compartment prior exportation cytoplasm and pVHL dynamic nuclear-cytoplasmic...
Objective . Myofibroblast transformation has been shown to be associated with the reactive oxygen species- (ROS-) producing enzyme NADPH oxidase (Nox4). Inhibition of transient receptor potential channel canonical type 3 (TRPC3) attenuates mitochondrial calcium handling and ROS production in vasculature hypertensive rats. However, it remains elusive whether TRPC3 regulates participates myofibroblast transdifferentiation during wound healing. Methods Results In this study, we demonstrated...
To investigate the regulatory effects of bio-intensity electric field on directional migration and microtubule acetylation in human epidermal cell line HaCaT, aiming to provide molecular theoretical basis for clinical treatment wound repair.