A5103200589- Neuroblastoma Research and Treatments
- Glioma Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Circadian rhythm and melatonin
- Advanced X-ray and CT Imaging
- Pancreatic and Hepatic Oncology Research
- Radiation Dose and Imaging
- Long-Term Effects of COVID-19
- Pancreatitis Pathology and Treatment
- Esophageal and GI Pathology
- Adrenal and Paraganglionic Tumors
- Lung Cancer Research Studies
- Neuroendocrine Tumor Research Advances
- Tryptophan and brain disorders
- Lymphoma Diagnosis and Treatment
- Occupational and environmental lung diseases
- Neuroscience of respiration and sleep
- Parvovirus B19 Infection Studies
- Cancer, Hypoxia, and Metabolism
- Pharmacological Receptor Mechanisms and Effects
- Osteomyelitis and Bone Disorders Research
- Intraperitoneal and Appendiceal Malignancies
- Cancer, Stress, Anesthesia, and Immune Response
- Ear and Head Tumors
- Histiocytic Disorders and Treatments
Beijing Friendship Hospital
2021-2025
Capital Medical University
2021-2025
Northwest A&F University
2025
National Natural Science Foundation of China
2023-2024
Cangzhou Central Hospital
2008-2023
Ghent University Hospital
2020-2021
People’s Hospital of Rizhao
2009-2020
Chronic recurrent multifocal osteomyelitis (CRMO), or chronic nonbacterial osteomyelitis, is difficult to diagnose. The accurate diagnosis of CRMO relies on comprehensive imaging examinations because its nature. In this regard, 18 F-FDG PET/CT has demonstrated significant utility in inflammatory diseases. This study tries determine the value FDG evaluation CRMO.
Abstract A 7-year-old boy with high-risk neuroblastoma underwent 123 I-MIBG SPECT/CT to evaluate the therapy response. The scan revealed abnormal uptake in left basal ganglion, indicating possibility of brain metastasis. Subsequent contrast-enhanced MRI, however, did not show any signal intensity ganglion. Follow-up scans at 3-month and 9-month also MIBG same area. case highlights false-positive
Tree peony seeds, traditionally used for edible oil production, are rich in α-linolenic acid (ALA). However, little attention is paid to their development as a healthcare food due bitter and astringent taste. The aim of this study was optimize the debittering process seeds on basis maintaining nutritional value identify compounds that cause taste bitterness. We first optimized by orthogonal experiments which reduced polyphenol content 90.25%, we measured main fatty composition, indicating...
Abstract An 8-year-old girl with refractory high-risk neuroblastoma underwent 68 Ga-DOTATATE PET/CT to evaluate the feasibility of potential 177 Lu-DOTATATE therapy. The scan showed multiple foci abnormal accumulation in bone region, indicating presence metastases. Unexpectedly, an tracer uptake was noted left lateral ventricle area. contrast-enhanced brain MRI obvious enhancement this lesion, suggesting diagnosis choroid plexus metastasis. Our case shows that might be useful diagnosing
Integrin αvβ3 expression is associated with sorafenib resistance in hepatocellular carcinoma (HCC). Therefore, monitoring its HCC may serve as a valuable indicator of the efficacy treatment. In this study, longitudinal positron emission tomography (PET) was performed to assess [18F]Alfatide II and [18F]fluorodeoxyglucose ([18F]FDG) suitable probes for evaluating treatment Huh-7 human (HCC) xenograft model. tumor cells were used establish both normal sorafenib-resistant cell lines, models...
Abstract Purpose To assess the prognosis predictive value of semi-quantitative metabolic parameters and tumoral activity based on 123 I-meta-iodobenzylguanidine (MIBG) SPECT/CT in pretreatment neuroblastoma (NB) patients. Methods A total 50 children (25 girls, 25 boys, median age 37 months, range 1-102 months) with newly diagnosed NB, consecutively examined pretherapeutic I-MIBG between 2018 2024, were included this retrospective study. The primary tumor measured, including Tmax/Lmax,...
An 8-year-old boy with high-risk neuroblastoma underwent routine follow-up 123I-MIBG scan, which revealed abnormal accumulation in right pleura, suggestive of potential metastasis. Histopathologic examination the biopsy specimen confirmed presence pleural The patient subsequently received four cycles chemotherapy. A scan after chemotherapy demonstrated no MIBG uptake, indicating remission However, 6 months later, a subsequent recurrent uptake pleura at same location as initial recurrence....
Abstract A 10-year-old girl with high-risk neuroblastoma underwent 123 I-MIBG SPECT/CT and 68 Ga-DOTATE PET/CT, which both showed multiple bone metastases. However, following 177 Lu-DOTATATE therapy, only Ga-DOTATATE PET/CT identified residual lesions negative results. The case emphasized the complementary role of after therapy.
Abstract 123 I-MIBG SPECT/CT was performed for follow-up in an asymptomatic 8-year-old girl with a history of neuroblastoma. The images showed unsuspected abnormal accumulation the head, which identified as hyperdense lesion dura increasing MIBG uptake, suggesting possibility metastasis from A brain MRI contrast remarkably enhanced beside confluence sinuses, mimicked meningioma. Results surgical pathology are consistent diagnosis dural
Abstract Contrast enhancement MRI of the brain and spine showed abnormal in intracranial spinal dural lesions a 6-year-old boy with high-risk neuroblastoma, suggesting possibility metastases. 123 I-MIBG SPECT/CT did not show any MIBG accumulation these lesions. However, 68 Ga-DOTATATE PET/CT obvious DOTATATE uptake metastatic Surgical pathology confirmed diagnosis metastasis. Concurrent metastases from neuroblastoma demonstrated by negative have been reported previously.
Abstract Objective This study aimed to explore the relationship between ramus intermedius (RI) and atherosclerosis in bifurcation of left coronary artery (LCA). Methods Screening patients who underwent CCTA from January September 2021, 100 with RI (RI group) without (no-RI were randomly enrolled, Evaluation distribution characteristics main artery(LM),Left anterior descending branch(LAD),left circumflex branch(LCX) proximal segment plaque distribution, measurement LAD-LCX...
Abstract A 5-year-old girl with high-risk neuroblastoma after therapy was evaluated by 123 I-MIBG SPECT/CT and 68 Ga-DOTATATE PET/CT. Contrast-enhancement brain MRI demonstrated 2 metastatic lesions in the right parietal lobe of brain. One lesion showed abnormal MIBG accumulation associated high density central posterior gyrus, whereas other did not show uptake. In contrast, increased uptake seen both lesions. Neuroblastoma cells were found cytological examination cerebrospinal fluid.
Multiple myeloma (MM) is a rare hematological malignancy, characterized by uncontrolled proliferation of plasma cells in the bone marrow. MM usually confined to marrow, however, it may occasionally infiltrate other tissues, which known as extramedullary plasmacytoma (EMP). The majority EMPs involve head and neck region, although different anatomical sites, including gastrointestinal tract, central nervous system, thyroid gland breast also be affected. simultaneous presentation EMP kidney...
Objective To observe the effects of 630 nm red light and 460 blue emitting diode irradiation on healing skin wounds in Japanese big-ear white rabbits. Methods The wound model was established with 8 Three parts vulnus each rabbit were used:two irradiated vertically by LED light,respectively(15 min/time),and distance between lights 15 cm;the 3rd part used as a control. On 21st day exposure to light,the number percentage area recorded treatment effect these two sources compared. HE staining...
Major depressive disorder (MDD) and generalized anxiety (GAD) are severe difficult-to-treat psychiatric illnesses with high rates of comorbidity. Although both disorders treated serotonergic based psychotropic agents, little is known on the influence neurotransmitter system occurrence comorbid GAD when clinically depressed. To investigate this poorly understood clinical question, we examined involvement frontolimbic post-synaptic 5-HT2A receptors in 20 medication-resistant depressed (MRD)...
Abstract Coexistence of Langerhans cell histiocytosis and ganglioneuroblastoma is rare seldom reported in the literature. A 3-year-old girl with underwent 18 F-FDG PET/CT imaging for staging, which demonstrated significant accumulation mandibles. Unexpectedly, a mild hypermetabolic soft mass was detected upper retroperitoneum. Results surgical pathology abdominal were consistent ganglioneuroblastoma.
The purpose of the study was to evaluate expression and function basic leucine zipper ATF-like transcription factor (BATF) in colorectal cancer (CRC), its correlation with 2-deoxy-2[
<title>Abstract</title> Background Glypican-2 (GPC2), a member of the GPC gene family, primarily functions in developing neural and thyroid cancer tissues, exerting influence on protein transduction, cellular proliferation differentiation, as well oncogenic signatures. GPC2 exhibits significant overexpression majority neuroblastoma (NB) samples while remaining nearly undetectable normal pediatric tissue samples. Methods Overall survival (OS) was employed key parameter to investigate...
Burkitt lymphoma (BL) is an exceptionally aggressive malignant neoplasm that arises from either the germinal center or post-germinal B cells. Patients with BL often present rapid tumor growth and require high-intensity multi-drug therapy combined adequate intrathecal chemotherapy prophylaxis, however, a standard treatment program for has not yet been established. It important to identify biomarkers predicting prognosis of BLs discriminating patients who might benefit therapy. Microarray data...