Guanyun Wang

ORCID: 0000-0003-1880-7163
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About
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Research Areas
  • Neuroblastoma Research and Treatments
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer, Hypoxia, and Metabolism
  • Pancreatic and Hepatic Oncology Research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Lymphoma Diagnosis and Treatment
  • Radiopharmaceutical Chemistry and Applications
  • Atrial Fibrillation Management and Outcomes
  • Neuroendocrine Tumor Research Advances
  • Renal cell carcinoma treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • IgG4-Related and Inflammatory Diseases
  • Prostate Cancer Treatment and Research
  • Cancer, Lipids, and Metabolism
  • CNS Lymphoma Diagnosis and Treatment
  • Medical Imaging Techniques and Applications
  • Pancreatitis Pathology and Treatment
  • CAR-T cell therapy research
  • Lung Cancer Research Studies
  • Vasculitis and related conditions
  • Adrenal and Paraganglionic Tumors
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Neurological disorders and treatments
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Rheumatoid Arthritis Research and Therapies

Beijing Friendship Hospital
2022-2025

Capital Medical University
2022-2025

Chinese PLA General Hospital
2020-2024

National Natural Science Foundation of China
2024

Chinese People's Liberation Army
2021-2023

Capital University
2023

PLA Academy of Military Science
2020

Chronic recurrent multifocal osteomyelitis (CRMO), or chronic nonbacterial osteomyelitis, is difficult to diagnose. The accurate diagnosis of CRMO relies on comprehensive imaging examinations because its nature. In this regard, 18 F-FDG PET/CT has demonstrated significant utility in inflammatory diseases. This study tries determine the value FDG evaluation CRMO.

10.1097/rlu.0000000000005216 article EN Clinical Nuclear Medicine 2024-04-05

It is crucial to assist neuroblastoma (NB) pediatric patients in accurate risk stratification based on the revised Children's Oncology Group (COG) classification system through non-invasive examinations. This study assessed diagnostic efficacy of integrating multiparametric 2-[18F]fluoro-D-glucose positron emission tomography/computed tomography (2-[18F]FDG PET/CT) metabolic parameters with clinical variables differentiate between high- and non-high-risk NB according COG system. A...

10.21037/qims-24-1111 article EN Quantitative Imaging in Medicine and Surgery 2025-02-24

Integrin αvβ3 expression is associated with sorafenib resistance in hepatocellular carcinoma (HCC). Therefore, monitoring its HCC may serve as a valuable indicator of the efficacy treatment. In this study, longitudinal positron emission tomography (PET) was performed to assess [18F]Alfatide II and [18F]fluorodeoxyglucose ([18F]FDG) suitable probes for evaluating treatment Huh-7 human (HCC) xenograft model. tumor cells were used establish both normal sorafenib-resistant cell lines, models...

10.1021/acs.molpharmaceut.4c01218 article EN Molecular Pharmaceutics 2025-02-23

Estimated glucose disposal rate (eGDR) is considered as a reliable alternative indicator of insulin resistance. However, the relationship between eGDR levels and mortality among individuals with cardiometabolic syndrome (CMS), well within different metabolic states in this population, remains unclear. We conducted cohort study on 9928 CMS participants from National Health Nutrition Examination Survey (NHANES) database 1999 to 2018. The population was evaluated using multivariable Cox...

10.1186/s13098-025-01636-5 article EN cc-by-nc-nd Diabetology & Metabolic Syndrome 2025-02-26

Using fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT), a multiparametric analysis will be performed in the differential diagnosis of patients with single solitary pulmonary lesion and extrapulmonary malignant tumor to discriminate between second primary lung cancer (SPLC) metastasis (PM). This study retrospectively studied 84 preoperative exams utilizing 18F-FDG PET/CT. complementing PET/CT parameters, composite model was developed. A...

10.1007/s12149-025-02034-7 article EN cc-by Annals of Nuclear Medicine 2025-03-05

The thioflavin T derivative, 11C-Pittsburgh-B (PIB), is used for Alzheimer's disease imaging because it specifically binds to β-amyloid protein deposits in the brain. aim of this study was estimate diagnostic value combined 11C-PIB positron emission tomography/magnetic resonance (PET/MR) cardiac amyloidosis (CA).We enrolled 23 heart failure patients with suspected CA based on echocardiographic and electrocardiograph findings. All underwent PET/MR non-cardiac biopsy within one week. We also...

10.3389/fcvm.2022.830572 article EN cc-by Frontiers in Cardiovascular Medicine 2022-03-16

This study aimed to assess the pretreatment 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) as a predictor of pathological treatment response (PTR) hepatocellular carcinoma (HCC) patients treated with PD-1 inhibitors and lenvatinib conversion therapy in BCLC stage C.All (n=20) underwent 18F-FDG PET/CT were surgery. Patients categorized into responders (n=9) non-responders (n=11) according PTR. The parameters PET/CT, including lesion size, SUVmean...

10.3389/fonc.2022.884372 article EN cc-by Frontiers in Oncology 2022-06-03

Evaluation of iodine-123-labeled metaiodobenzylguanidine single-photon emission computed tomography/computed tomography based on the International Society Pediatric Oncology Europe Neuroblastoma score in children with neuroblastoma

10.21037/qims-22-1120 article EN Quantitative Imaging in Medicine and Surgery 2023-05-09

Post-transplant lymphoproliferative disorder (PTLD) is a significant complication after liver transplantation. Research on the diagnostic value of Fluorine-18 fluorodeoxyglucose positron emission tomography/computerized tomography (

10.21037/qims-23-1059 article EN cc-by-nc-nd Quantitative Imaging in Medicine and Surgery 2024-01-26

Purpose To investigate the diagnostic value of 18 F-fluorodeoxyglucose positron emission tomography ( F-FDG PET), as an imaging biomarker, for predicting pathological response and prognosis unresectable hepatocellular carcinoma (HCC) patients treated with Lenvatinib programmed cell death protein 1 (PD-1) inhibitors a conversion therapy. Methods A total 28 HCC BCLC stage B or C were PD-1 before surgery. The PET/CT scans acquired pre- (scan-1) post-conversion therapy (scan-2). maximum...

10.3389/fimmu.2023.1151967 article EN cc-by Frontiers in Immunology 2023-05-05

18F-fluorodeoxyglucose positron emission tomography-computerized tomography (18F-FDG PET-CT) has demonstrated high sensitivity in the diagnosis of autoimmune pancreatitis (AIP) and pancreatic ductal adenocarcinoma (PDAC), while also exhibiting ability to distinguish AIP from PDAC lesions. The objective this investigation was assess efficacy multiparametric 18F-FDG PET with serological examination for distinguishing focal (f-AIP) PDAC.A total 127 patients (43 f-AIP 84 PDAC) who received...

10.21037/qims-23-88 article EN Quantitative Imaging in Medicine and Surgery 2023-08-29

Colorectal cancer (CRC) is the third most frequent cause of cancer-related death, while tumor/node/metastasis (TNM) stage American Joint Committee on Cancer guideline making treatment strategy and predicting survival. The aim this study to investigate association preoperative 2-deoxy-2[

10.21037/qims-23-966 article EN Quantitative Imaging in Medicine and Surgery 2023-12-29

Purpose: Coronary artery disease (CAD) and atrial fibrillation (AF) often coexist lead to a much higher risk of mortality in the elderly population. The aim this study was investigate whether CHA2DS2-VASc score could predict death patients with CAD AF. Methods: Hospitalized aged ≥65 years diagnosis AF were recruited consecutively. Patients divided into 5 groups according (≤2, =3, =4, =5, ≥6). At least 1-year follow-up carried out for assessment all-cause death. Results: A total 1,579...

10.3389/fcvm.2021.805234 article EN cc-by Frontiers in Cardiovascular Medicine 2021-12-24

To evaluate the diagnostic performance of combined multiparametric 18F-fluorodeoxyglucose positron emission tomography (18FDG PET) with clinical characteristics in differentiating thymic epithelial tumors (TETs) from lymphomas.A total 173 patients 80 TETs and 93 lymphomas who underwent 18F-FDG PET/CT before treatment were enrolled this retrospective study. All confirmed by pathology, baseline data also collected. The semi-parameters PET/CT, including lesion size, SUVmax (maximum standard...

10.1186/s12885-022-09988-1 article EN cc-by BMC Cancer 2022-08-16

To evaluate 18F-fluorodeoxyglucose positron emission tomography (18FDG PET) and clinical parameters to differentiate rheumatoid arthritis (RA) polymyalgia rheumatic (PMR). Patients Methods. This retrospective study evaluated 54 patients with suspected RA (n = 23) PMR 31) who underwent 18F-FDG PET/CT before treatment. The complete diagnosis was based on each classification criterion at least followed up for 6 months. Demographic data were also collected. Semiquantitative analysis (maximum...

10.1155/2022/9614678 article EN cc-by Contrast Media & Molecular Imaging 2022-01-01

Abstract Objective To evaluate the diagnostic value of a multiparameter model based on 18 F-fluorodeoxyglucose positron emission tomography ( F-FDG PET) metabolic parameters and clinical variables in differentiating nonmetastatic gallbladder cancer (GBC) from cholecystitis. Patients methods In total, 122 patients (88 GBC 34 cholecystitis patients) with space-occupying lesions who underwent PET/CT were included. All received surgery pathology, baseline characteristics data also collected. The...

10.1186/s12885-023-10599-7 article EN cc-by BMC Cancer 2023-02-06

Abstract Background The predictive value of 18 F-fluorodeoxyglucose positron emission tomography/computed tomography ( F-FDG PET/CT) metabolic parameters for predicting AIP relapse is currently unknown. This study firstly explored the PET/CT as predictors type 1 relapse. Methods multicenter retrospective cohort analyzed 51 patients who received prior to treatment and did not receive maintenance therapy after remission. collected baseline characteristics clinical data conducted qualitative...

10.1186/s12876-023-03113-7 article EN cc-by BMC Gastroenterology 2024-01-17

Background: Accurate and early detection of neuroblastoma (NB) metastases is an urgent requirement for clinical diagnosis treatment. This study aimed to explore the value a new diagnostic model combining I - Metaiodobenzylguanidine (MIBG) scintigraphy, minimal residual disease (MRD) examination parameters in detecting NB. Methods: A total 76 pediatric patients (41 males 35 females) with both I-MIBG scintigraphy bone marrow (BM) MRD were retrospectively analyzed. detected using Quantitative...

10.22541/au.171524013.37115338/v1 preprint EN Authorea (Authorea) 2024-05-09

To investigate the value of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed (CT) semi-quantitative parameters, including lesion diameter, maximum standardized uptake (SUVmax), corrected for lean body mass (SULmax), metabolic volume (MLV), and total glycolysis (TLG), classifying hepatic echinococcosis. In total, 20 patients with 36 echinococcosis lesions were included in study. Overall, these categorized as cystic (HCE) or alveolar (HAE) according to pathological...

10.1186/s12880-024-01371-9 article EN cc-by-nc-nd BMC Medical Imaging 2024-07-31

<title>Abstract</title> Background Glypican-2 (GPC2), a member of the GPC gene family, primarily functions in developing neural and thyroid cancer tissues, exerting influence on protein transduction, cellular proliferation differentiation, as well oncogenic signatures. GPC2 exhibits significant overexpression majority neuroblastoma (NB) samples while remaining nearly undetectable normal pediatric tissue samples. Methods Overall survival (OS) was employed key parameter to investigate...

10.21203/rs.3.rs-5242931/v1 preprint EN cc-by Research Square (Research Square) 2024-10-22
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