A5060894274- Nanopore and Nanochannel Transport Studies
- Nitric Oxide and Endothelin Effects
- Advanced biosensing and bioanalysis techniques
- Advanced Memory and Neural Computing
- Analytical Chemistry and Sensors
- Electrochemical Analysis and Applications
- Sulfur Compounds in Biology
- Microfluidic and Capillary Electrophoresis Applications
- Biosensors and Analytical Detection
- Fuel Cells and Related Materials
- Electrochemical sensors and biosensors
- Anodic Oxide Films and Nanostructures
- Electrostatics and Colloid Interactions
- Quantum-Dot Cellular Automata
- Advanced Chemical Sensor Technologies
- Renin-Angiotensin System Studies
- Water Quality Monitoring and Analysis
- Mass Spectrometry Techniques and Applications
- Neuroscience and Neural Engineering
- Neural dynamics and brain function
- Microfluidic and Bio-sensing Technologies
- Membrane-based Ion Separation Techniques
- Graphene research and applications
- Electron Spin Resonance Studies
- Surface Chemistry and Catalysis
University of Manchester
2022-2024
Henry Royce Institute
2022-2024
Centre National de la Recherche Scientifique
2014-2021
CEA Grenoble
2019-2021
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2019-2021
Université Grenoble Alpes
2019-2021
Agence de la transition écologique
2020
Institut Nanosciences et Cryogénie
2019
Université Paris Cité
2014-2018
Unité de Technologies Chimiques et Biologiques pour la Santé
2015-2018
Fine-tuned ion transport across nanoscale pores is key to many biological processes, including neurotransmission. Recent advances have enabled the confinement of water and ions two dimensions, unveiling properties inaccessible at larger scales triggering hopes reproducing ionic machinery systems. Here we report experiments demonstrating emergence memory in aqueous electrolytes (sub)nanoscale channels. We unveil types nanofluidic memristors depending on channel material confinement, with...
Angstrom-scale fluidic channels are ubiquitous in nature and play an important role regulating cellular traffic, signaling, responding to stimuli. Synthetic angstrom now a reality with the emergence of several cutting-edge bottom-up top-down fabrication methods. In particular, use atomically thin 2D materials nanotubes as components build conduits has pushed limits scale. Here, we provide overview recent developments methods for nano- angstrofluidic while categorizing them on basis...
Bipolar electrochemistry (BPE) is a powerful method based on the wireless polarization of conductive object that induces asymmetric electroactivity at its two extremities. A key physical limitation BPE size because shorter object, larger potential necessary for sufficient polarization. Micrometric and nanometric objects are thus extremely difficult to address by due very high potentials required, in order tens kV or more. Herein, synergetic actions planar micropores integrated microfluidic...
S-Nitrosothiols (RSNOs) are carriers of nitric oxide (NO) and have important biological activities. We propose here the use gold nanoparticles (AuNPs) NO-selective amperometric microsensor for detection quantification S-nitrosoglutathione (GSNO) as a step toward determination plasma RSNOs. AuNPs were used to decompose RSNOs with quantitative release free NO which was selectively detected microsensor. The optimal [GSNO]/[AuNPs] ratio determined, corresponding an excess AuNP surface relative...
A disposable microfluidic paper-based analytical device (μPAD) was developed to easily analyse different S-nitrosothiols (RSNOs) through colorimetric measurements. RSNOs are carriers of nitric oxide (NO) that play several physiological and physiopathological roles. The quantification relies on their decomposition using protocols the detection final product, NO or nitrite. μPADs were fabricated by wax printing technology in a geometry containing one central zone for sample inlet eight...
The combination of bipolar electrochemistry (BE), as a wireless electrochemical approach, and electrochemiluminescence (ECL) an imaging readout is successful strategy with wide range analytical applications. However, small conductive entities such micrometric nanometric objects are particularly difficult to polarize by BE since they require extremely high electric fields. In order circumvent this issue due intrinsic limitations BE, we elaborated solid-state micropore, decorated...
S‐Nitrosothiols (RSNO) are composed of a NO group bound to the sulfhydryl peptide or protein. RSNO very important biological molecules, since they have many effects on human health. easily naturally decomposed by metal ions, light, and heat, with different kinetics. They can furthermore undergo transnitrosation (NO moieties exchange), which is crucial point in physiological conditions concentration ratios between nitrosothiols key factor physiopathological processes. There therefore great...
Abstract This work depicts the original combination of electrochemiluminescence (ECL) and bipolar electrochemistry (BPE) to map in real‐time oxidation silicon microchannels. We fabricated model silicon‐PDMS microfluidic chips, optionally containing a restriction, monitored evolution surface reactivity using ECL. BPE was used remotely promote ECL at inside channels. The effects fluidic design, applied potential resistance channel (controlled by configuration) on polarization oxide formation...
S-nitrosothiols (RSNOs) are very important biomolecules that play crucial roles in many physiological and physiopathological processes. They act as NO-donors candidates for future medicines. Their identification quantitation therefore biomedical applications. One, two or more RSNOs can then be combined to design a drug therefore, the quantification of each is establish an acceptable quality control process. Till date, miniaturized devices have been used detect based on their total without...
Abstract S‐nitrosothiols (RSNOs) are composed of nitric oxide (NO) bound to the sulfhydryl group amino acids peptides or proteins. There is a great interest for their quantitation in biological fluids as they have crucial impact on physiological and pathophysiological events. Most analytical methodologies RSNOs based decomposition followed by detection released NO. In order obtain optimal sensitivity each method, total highly desired. The can be obtained using catalytically active metal...
Abstract Angstrom‐scale fluidic channels offer immense potential for applications in areas such as desalination, molecular sieving, biomolecular sequencing, and dialysis. Inspired by biological ion channels, nano‐ angstrom (Å)‐scale are fabricated that mimic these or atomic‐scale dimensions. At the Å‐scale, exhibit unique phenomena, including selective transport, osmotic energy generation, fast water gas flows, neuromorphic memory. However, practical utilization of Å‐scale is often hindered...
Fine-tuned ion transport across nanoscale pores is key to many biological processes such as neurotransmission. Recent advances have enabled the confinement of water and ions two dimensions, unveiling properties unreachable at larger scales triggering hopes reproduce ionic machinery systems. Here we report experiments demonstrating emergence memory in aqueous electrolytes (sub)nanoscale channels. We unveiled types nanofluidic memristors, depending on channel material confinement, with from...
Ion-selective channels play a key role in physiological processes and are used many technologies. While biological can efficiently separate same-charge ions with similar hydration shells, it remains challenge to mimic such exquisite selectivity using artificial solid-state channels. Although, there several nanoporous membranes that show high respect certain ions, the underlying mechanisms based on hydrated ion size and/or charge. There is need rationalize design of make them capable...
Angstrom-scale fluidic channels are ubiquitous in nature, and play an important role regulating cellular traffic, signaling, responding to stimuli. Synthetic now a reality with the emergence of several cutting-edge bottom-up top-down fabrication methods. In particular, use atomically thin two dimensional (2D) materials nanotubes as components build conduits has pushed limits Angstrom-scale. Here, we provide overview recent developments methods for nano- angstrofluidic while categorizing them...
Abstract The localized functionalization of pores and channels micrometric sub‐micrometric sizes is a bottleneck in surface chemistry. A method for the regioselective chemical planar presented, that are, restrictions microfluidic channels, here made SiO 2 ‐coated silicon. This strategy, based on bipolar electrochemistry, exploits combined presence constriction deoxidation pattern within pore affects electrical field distribution inside channel. It not only shown it capable regioselectively...