- Mechanical and Optical Resonators
- Advanced MEMS and NEMS Technologies
- Nanowire Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Microfluidic and Bio-sensing Technologies
- Nanofabrication and Lithography Techniques
- Electrowetting and Microfluidic Technologies
- Force Microscopy Techniques and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Acoustic Wave Resonator Technologies
- Silicon Nanostructures and Photoluminescence
- Photonic and Optical Devices
- Analytical Chemistry and Sensors
- Molecular Junctions and Nanostructures
- Biosensors and Analytical Detection
- Advanced Biosensing Techniques and Applications
- Magnetism in coordination complexes
- Semiconductor materials and devices
- Innovative Microfluidic and Catalytic Techniques Innovation
- Magnetic properties of thin films
- Advanced Sensor and Energy Harvesting Materials
- Nanopore and Nanochannel Transport Studies
- Nanomaterials and Printing Technologies
- Wireless Power Transfer Systems
- Advanced optical system design
Centre National de la Recherche Scientifique
2016-2025
Laboratoire d'Analyse et d'Architecture des Systèmes
2016-2025
Georgia Institute of Technology
2002-2025
Université de Toulouse
2014-2025
Georgia Tech Lorraine
2019-2024
Atlanta Technical College
2022
Roche (France)
2005-2021
Roche (Sweden)
2021
Université Toulouse III - Paul Sabatier
2010-2017
Nanobiotix (France)
2016
The fabrication of large-area vertical junctions with a molecular spin-crossover complex displaying concerted changes spin degrees freedom and charge-transport properties is reported. Fabricated devices allow spin-state switching in the layer to be triggered probed by optical means, while detecting associated electrical resistance junctions. As service our authors readers, this journal provides supporting information supplied authors. Such materials are peer reviewed may re-organized for...
Molecular spin crossover complexes are promising candidates for mechanical actuation purposes. The relationships between their crystal structure and properties remain, however, not well understood. In this study, combining high pressure synchrotron X-ray diffraction, nuclear inelastic scattering, micromechanical measurements, we assessed the effective macroscopic bulk modulus (B = 11.5 ± 1.5 GPa), Young's (Y 10.9 1.0 Poisson's ratio (ν 0.34 0.04) of complex [FeII(HB(tz)3)2] (tz...
Abstract We report on a bistable MEMS device actuated by spin‐crossover molecules. The consists of freestanding silicon microcantilever with an integrated piezoresistive detection system, which was coated 140 nm thick film the [Fe(HB(tz) 3 ) 2 ] (tz=1,2,4‐triazol‐1‐yl) molecular complex. Switching from low‐spin to high‐spin state ferrous ions at 338 K led reversible upward bending cantilever in agreement change lattice parameters strong mechanical coupling also evidenced decrease...
Most of review articles or even books dedicated to biosensing issues are organized by the generally admitted scheme a biosensor. Subsequently, biological receptors, modified surfaces (and ways specifically modify those using established and/or chemical recipes), and transduction techniques thoroughly addressed in this precise order. In review, we deliberately decided break conventional way providing uniquely addressing biomolecules’ immobilization methods onto solid surface...
Abstract [Fe II (Htrz) 2 (trz)](BF 4 ) spin crossover particles of 85 nm mean size are dispersed in an SU‐8 polymer matrix and spray‐coated onto silicon microcantilevers. The subsequent photothermal treatment the resist leads to micrometer thick, smooth, homogeneous coatings, which exhibit well‐reproducible actuation upon thermally induced transition. amplitude as a function temperature is accurately determined by combining integrated piezoresistive detection with external optical...
The development of advanced techniques fabrication three-dimensional (3D) microenvironments for the study cell growth and proliferation has become one major motivations material scientists bioengineers in past decade. Here, we present a novel residueless 3D structuration technique poly(dimethylsiloxane) (PDMS) by water-in-PDMS emulsion casting subsequent curing process temperature-/pressure-controlled environment. Scanning electron microscopy X-ray microcomputed tomography allowed us to...
DNA size separation followed by purification and enrichment constitute essential operations for genetic engineering.
Silicon MEMS cantilevers coated with a 200 nm thin layer of the molecular spin crossover complex [Fe(H2B(pz)2)2(phen)] (H2B(pz)2 = dihydrobis(pyrazolyl)borate and phen 1,10-phenantroline) were actuated using an external magnetic field their resonance frequency was tracked by means integrated piezoresistive detection. The light-induced spin-state switching molecules from ground low to metastable high state at 10 K led well-reproducible shift cantilever's (Δfr −0.52 Hz). Control experiments...
The acceleration of climatic, digital, and health challenges is testing scientific communities. Scientists must provide concrete answers in terms technological solutions to a society which expects immediate returns on the public investment. We are living such scenario global scale with pandemic crisis COVID-19 where expectations for virological serological diagnosis tests have been still gigantic. In this Perspective, we focus class biosensors (mechanical biosensors) ubiquitous literature...
Abstract Multiplexed remote bio‐detection is demonstrated through an optical waveguide assembly coated with interferometric layers. Image conduits (IC)s, composed of 3012 individual cores, are layers tantalum pentoxide (Ta 2 O 5 ) and silica (SiO to transform each core into a sensitive sensor. The spectral response the IC as function refractive index (RI) changes obtained compared simulated one. experimental sensitivities resolutions cores assessed in detection mode by imaging assembly. For...
<title>Abstract</title> We present a simple and robust process for fabricating III-Nitride (III-N) mechanical resonators on flexible metal substrates. This method combines Van der Waals epitaxy of III-N epilayers with the deposition thick stressor atop layers. During thermal treatment, 30 µm deposited 300 nm AlGaN / 500 GaN layer grown 3 two-dimensional hexagonal-Boron Nitride (2D h-BN) release layer, initiates one-step Self-Lift-Off Transfer (SLOT) process. effectively transfers...
Abstract The monolithic integration of high‐performance magnets into microfabricated devices remains a technological challenge despite the great interest for telecommunications, automotive, biomedical or space applications. Here 50 µm thick sputtered arrays NdFeB micromagnets functional micro‐electro mechanical system (MEMS) in‐plane electromagnetic vibration energy harvester is reported. A combination analytical modeling and numerical simulations guided design magnet along with ad‐hoc...
The use of a parallel cantilever-based deposition system as an electrospotting tool in picoliter volumes is demonstrated. Applied conjunction with polypyrrole electrochemistry, this generic approach for fabricating biochips optimized oligonucleotide chips featuring micrometer spots different sequences high reproducibility and specificity (see figure).
Bipolar electrochemistry (BPE) is a powerful method based on the wireless polarization of conductive object that induces asymmetric electroactivity at its two extremities. A key physical limitation BPE size because shorter object, larger potential necessary for sufficient polarization. Micrometric and nanometric objects are thus extremely difficult to address by due very high potentials required, in order tens kV or more. Herein, synergetic actions planar micropores integrated microfluidic...
The development of sensitive methods for in situ detection biomarkers is a real challenge to bring medical diagnosis step forward. proof-of-concept remote multiplexed biomolecular interaction through plasmonic optical fiber bundle demonstrated here. strategy relies on optic biosensor designed from 300 µm diameter composed 6000 individual fibers. When appropriately etched and metallized, each exhibits specific properties. surface plasmon resonance phenomenon occurring at the enables measure...
We have used fountain pen microlithography to deposit arrays of molecularly imprinted polymer microdots on flat substrates. visualize analyte binding the dots by fluorescence microscopy with aid fluorescein as a model analyte. Elution and readsorption MIP were possible if porosity was improved sacrificial polymeric porogen. The imprinting effect confirmed using compounds structurally related fluorescein. In addition, we show another specific 2,4-D that, apart from direct measurement...
In this work, we present a novel fabrication process that enables the monolithic integration of lateral porous silicon membranes into single-layer planar microchannels. This technique relies on patterning local electrodes to guide pore formation horizontally within membrane and use silicon-on-insulator substrates spatially localize channel depth. The feasibility our approach is studied by current flow analysis using finite element method supported creating 10 μm long mesoporous 20 deep...
Abstract We report on a bistable MEMS device actuated by spin‐crossover molecules. The consists of freestanding silicon microcantilever with an integrated piezoresistive detection system, which was coated 140 nm thick film the [Fe(HB(tz) 3 ) 2 ] (tz=1,2,4‐triazol‐1‐yl) molecular complex. Switching from low‐spin to high‐spin state ferrous ions at 338 K led reversible upward bending cantilever in agreement change lattice parameters strong mechanical coupling also evidenced decrease...
We present a quantitative study on the fabrication of microlenses using low-cost polymer dispending technique. Our method is based use silicon micro-cantilever robotized spotter system. first give detailed description In second part, fabricated are fully characterized by means SEM (Scanning Electron Microscope), AFM (Atomic Force Microscopy) non contact optical profilometry and Mach-Zehnder interferometry. Diameters in range [25-130mum] obtained with an average surface roughness 2.02nm....