- Neonatal Respiratory Health Research
- Maternal and Perinatal Health Interventions
- Healthcare Systems and Practices
- Global Maternal and Child Health
- Maternal and fetal healthcare
- Health, Medicine and Society
- Emergency and Acute Care Studies
- Pregnancy and preeclampsia studies
- Neonatal and fetal brain pathology
- Child and Adolescent Health
- Maternal Mental Health During Pregnancy and Postpartum
- Infant Development and Preterm Care
- Assisted Reproductive Technology and Twin Pregnancy
- Preterm Birth and Chorioamnionitis
- Gestational Diabetes Research and Management
- Adolescent and Pediatric Healthcare
- Neonatal Health and Biochemistry
- COVID-19 Impact on Reproduction
- Pregnancy and Medication Impact
- Social Policies and Family
- Birth, Development, and Health
- Reproductive Health and Contraception
- Pregnancy-related medical research
- Childhood Cancer Survivors' Quality of Life
- Ethics in Clinical Research
Centre Hospitalier Régional et Universitaire de Nancy
2015-2024
Centre de Recherche Épidémiologie et Statistique
2019-2024
Sorbonne Paris Cité
2019-2024
Inserm
2009-2024
Université Paris Cité
2019-2024
Ministère des Solidarités et de la Santé
2018-2024
Maternité Port Royal
2024
Fédération française de cardiologie
2023
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2022
Santé Publique France
2020
OBJECTIVE: In very preterm infants, there is a high risk for impaired kidney function; therefore, access to normal ranges of glomerular filtration rate (GFR) age and definition reliable range clearance essential. Despite this, updated GFR reference values use in clinical practice are not available. The objective this study was determine infants aged 27 31 weeks' gestation. METHODS: This multicenter, prospective cohort study. Infants were recruited the before 48 hours life. Glomerular...
Abstract This study aimed to identify the risk factors for placenta accreta spectrum (PAS) in women who had at least one previous cesarean delivery and a previa or low-lying. The PACCRETA prospective population-based took place 12 regional perinatal networks from 2013 through 2015. All with more prior cesareans low lying were included. Placenta was diagnosed according standardized clinical histological criteria. Of 520,114 deliveries, 396 fulfilled inclusion criteria; 108 classified PAS...
Abstract Stillbirth rates have stalled or increased in some European countries during the last decade. We investigate to what extent time-trends and between-country differences stillbirth are explained by changing prevalence of advanced maternal age teenage pregnancies multiple births. analysed data on stillbirths live births multiplicity from 2010 2021 25 using Kitagawa decomposition separate rate into compositional components. Rates significantly decreased six countries, but two. Changes...
Objective To describe and compare the characteristics of women with placenta accreta spectrum (PAS) their pregnancy outcomes according to presence praevia a prior caesarean section. Design Prospective population‐based study. Setting All 176 maternity hospitals eight French regions. Population Two hundred forty‐nine PAS, from source population 520 114 deliveries. Methods Women PAS were classified into two risk‐profile groups, or without high‐risk combination (or an anterior low‐lying...
Abstract Background Despite concerns about worsening pregnancy outcomes resulting from healthcare restrictions, economic difficulties and increased stress during the COVID-19 pandemic, preterm birth (PTB) rates declined in some countries 2020, while stillbirth appeared stable. Like other shocks, pandemic may have exacerbated existing socioeconomic disparities pregnancy, but this remains to be established. Our objective was investigate changes PTB by status (SES) European countries. Methods...
There are wide disparities in neonatal mortality rates (NMRs, deaths <28 days of life after live birth per 1000 births) between countries Europe, indicating potential for improvement. Comparing country-specific patterns births and with low can facilitate the development effective intervention strategies.
Summary Anaemia is frequently diagnosed during pregnancy. However, there are few data regarding its incidence, and the association with severe maternal morbidity remains uncertain potentially biased in high‐resource countries. The purpose of this study was to explore between gestational anaemia acute after delivery. We performed a cohort‐nested case‐control analysis from epidemiology mortality (EPIMOMS) prospective conducted six French regions (2012–2013, n = 182,309 deliveries). There were...
This study aimed to describe the health status of children and how social deprivation affects their use healthcare services mortality. Children living in mainland France were selected from national data system (SNDS) on date birth or birthday 2018 (< 18 years) followed for one year. Information included reimbursements, long-term chronic diseases (LTDs) eligible 100% reimbursement, geographic index (FDep) by quintile (Q5 most disadvantaged), individual complementary universal insurance (CMUc)...
Abstract Background The Baby-Friendly Hospital Initiative (BFHI) is associated with improved breastfeeding outcomes in many high-income countries including the UK and USA, but its effectiveness has never been evaluated France. We investigated impact of BFHI on rates French maternity units 2010, 2016 2021 to assess if aids reduce inequalities breastfeeding. Methods examined (exclusive, mixed any breastfeeding) mothers singleton full-term newborns using 2010 (n = 13 075), 10 919) 209) National...
Inhaled nitric oxide (iNO), commonly used for hypoxic neonates, may react with haemoglobin to form methaemoglobin (MetHb). MetHb monitoring during iNO therapy has been questioned since low doses of are used.To evaluate the incidence and identify risk factors associated elevated in neonates treated iNO.Neonates who were had at least one measurement included. Demographic characteristics methods administration (dosage, duration) time each analysed.Four hundred fifty-two measurements from 81...
<h3>Objective</h3> To determine the impact on glomerular filtration rate (GFR) and tubular function of drugs prescribed to very preterm infants during first week life. <h3>Design</h3> Prospective multicentre cohort study aged 27–31 weeks gestation. <h3>Methods</h3> GFR was measured day 2, then weekly for 1 month, with 12-h urine collection by a standardised kinetic Jaffe method. Infants were classified into two groups according their 7 (‘Low GFR’ ‘High GFR’) regard median reference...
Facilitating factors and barriers to breast milk feeding (BMF) for preterm infants have been mainly studied in very populations, but little is known about moderate infants. We aimed analyze hospital unit characteristics BMF policies associated with at discharge born 32 34 weeks' gestation. EPIPAGE-2, a French national cohort of births, included 883 investigated kangaroo care the first 24 hr, early involvement parents support, volume unit, information given mothers hospitalized threatened...
To assess the feasibility of placental and myometrial vascularization quantification using 3D power Doppler ultrasonography.3D standardized acquisition was performed in mid part utero-placental unit, once, 38 patients undergoing normal pregnancies between 15 39 weeks. Vascularization parameters (VI, FI, VFI) placentae myometrium were measured. Intra inter-observer, as well inter-acquisition reproducibility evaluated.Intra-class Correlation Coefficient measurements at least 0.94 for...
Abstract Background This study was designed to identify factors associated with at least one emergency department (ED) visit and those without consultation by a general practitioner or paediatrician (GPP) before ED visit. Levels of annual consumption healthcare services as function the number were reported. Methods retrospective focused on children < 18 years age living in mainland France followed for one-year after their birth birthday 2018. Children selected from national health data...
To compare different antibiotic prophylaxis administered after preterm premature rupture of membranes to determine whether any were associated with differences in obstetric and/or neonatal outcomes neurodevelopmental at 2 years corrected age.Prospective, nationwide, population-based EPIPAGE-2 cohort study infants.France, 2011.We included 492 women a singleton pregnancy and diagnosis 24-31 weeks. Exclusion criteria contraindication expectant management or indication for therapy other than...