A5072542236- Lung Cancer Diagnosis and Treatment
- Transplantation: Methods and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Tracheal and airway disorders
- Advanced X-ray and CT Imaging
- Mechanical Circulatory Support Devices
- Congenital Diaphragmatic Hernia Studies
- Pleural and Pulmonary Diseases
- Salivary Gland Tumors Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Metastasis and carcinoma case studies
- Autophagy in Disease and Therapy
- Drug-Induced Adverse Reactions
- Ferroptosis and cancer prognosis
- Heparin-Induced Thrombocytopenia and Thrombosis
- Myasthenia Gravis and Thymoma
- Hydrogen's biological and therapeutic effects
- Organ Transplantation Techniques and Outcomes
- Cancer, Stress, Anesthesia, and Immune Response
- Lung Cancer Research Studies
- Esophageal Cancer Research and Treatment
- Cancer survivorship and care
- Inflammatory Biomarkers in Disease Prognosis
University of Tokyo Hospital
2020-2023
St. Luke's International Hospital
2017-2023
The University of Tokyo
2021-2022
St. Luke's International University
2020
Shizuoka General Hospital
2018
Macrophages contribute to post-transplant lung rejection. Disulfiram (DSF), an anti-alcoholic drug, has anti-inflammatory effect and regulates macrophage chemotactic activity. Here, we investigated DSF efficacy in suppressing acute rejection post-lung transplantation. Male Lewis rats (280–300 g) received orthotopic left transplants from Fisher 344 (minor histocompatibility antigen-mismatched transplantation). (0.75 mg/h) monotherapy or co-solvent only (50% hydroxypropyl-β-cyclodextrin) as...
The short-term efficacy of virtual-assisted lung mapping (VAL-MAP), a preoperative bronchoscopic multi-spot lung-marking technique, has been confirmed in 2 prospective multicentre studies. objectives this study were to analyse the local recurrence and survival patients enrolled these studies, long-term.Of 663 559 patients' follow-up data collected. After excluding those who did not undergo VAL-MAP, whose resection was for curative intent, underwent concurrent without or eventually lobectomy...
We report a case with suggestive antiprogrammed death-1 inhibitor-related pneumonitis in an endometrial cancer patient. This presented fever and cough after three dosages of nivolumab. Computed tomography initially showed centrilobular nodularities unilateral lung, which was compatible aspiration pneumonia. However, diffuse ground-glass opacities (GGO) rapidly developed the lung over 4 days despite use broad-spectrum antibiotics. Development GGO considered to be related nivolumab-mediated...
Abstract Background Although the number of patients who undergo extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation is increasing worldwide, there are few reports on after long-term ECMO (more than 1 month). We report rare case successful bilateral in Japanese patient 5 months veno-venous (VV)-ECMO support. Case presentation A 27-year-old man underwent bone marrow (BMTx) with fully matched human leukocyte antigen typing was diagnosed bronchiolitis obliterans caused...
To investigate the accuracy of a segment-counting method in predicting lung function and volume after stapler-based thoracoscopic segmentectomy comparison with lobectomy.Between 2014 2018, patients who underwent these procedures were retrospectively reviewed. Thoracic computed tomography spirometry data before 1 year surgery assessed. We evaluated differences between predicted values using actual postoperative for each group. Sub-analyses also performed to assess impact number staples...
This study aimed to develop a prediction model for less invasive lesions of pathological Stage IA adenocarcinomas.We retrospectively evaluated 121 from 114 patients with adenocarcinoma who underwent surgery after fluorodeoxyglucose positron emission tomography and high-resolution computed tomography. Less were in situ minimally adenocarcinoma. The 3D parameter, solid tumour ratio, was the volume ratio part whole tumour. 2D parameter consolidation-to-tumour ratio. maximum standardized uptake...
Abstract Purpose It is unknown whether intraoperative needle biopsy (INB) predisposes to the postoperative recurrence of lung cancer and compromises prognosis these patients. We conducted this study identify effect INB before lobectomy on rate patients with nonsmall cell (NSCLC). Methods The subjects retrospective were 953 pathological stage I–III NSCLC who underwent between 2001 2016. divided into two groups: group ( n = 94) non-INB 859). After propensity score matching (PSM), we compared...
Even after transplantation of favourable donor lungs, some recipients require prolonged weaning from mechanical ventilation, indicating a poor prognosis. We investigated the effects ventilation (PMV) for >14 days on recovery and survival patients who underwent cadaveric lung in relation to their physical traits.We retrospectively reviewed (age ≥15 years) at single centre between April 2015 December 2020 classified them into PMV non-PMV groups (>14 ≤14 postoperatively, respectively). The...
Central MessageA case of successful radical pulmonary lobectomy and lymphadenectomy for a lung cancer patient with Fontan circulation is presented.See Commentary on page 166. A presented. See 26-year-old man diagnosed primary the left upper lobe was referred to our hospital. Contrast-enhanced computed tomography chest showed mass in anterior segment (Figure 1, A). No evidence hilar mediastinal lymphadenopathy or metastatic lesions detected. Transbronchial biopsy at referring hospital had...
When performing living-donor lobar lung transplantation on small children of height 100 cm or under, accommodation an oversized adult graft is problematic, sometimes necessitating single in combination with contralateral pneumonectomy. We here report a unique case 9-year-old boy congenital pulmonary hypoplasia. Although he was 104 tall, and the available lower lobe appeared to be oversized, his right hypoplastic, resulting mediastinum being shifted thus already showing...
Nondisappearing subsolid nodules requiring follow-up are often detected during lung cancer screening, but changes in their invasiveness can be overlooked owing to slow growth. We aimed develop a method for automatic identification of invasive tumors among multiple health checkups using radiomics technology based on low-dose computed tomography (LD-CT) and examine its effectiveness. examined patients who underwent LD-CT screening from 2014 2019 had adenocarcinomas resected after 5-year...
Living-donor lobar lung transplantation (LDLLT) is a well-established surgical procedure with favorable outcomes; however, the frequency of readmission and costs in LDLLT are poorly understood. Here, we aimed to compare healthcare readmissions at 90 days 1 year after index discharge cadaveric (CLT) evaluate reasons for in-hospital mortality. In this retrospective cohort study, used Diagnosis Procedure Combination database, nationwide inpatient database Japan obtain initial data all patients...
<b>Background:</b> Quantification of daily physical activity (PA) in patients with lung cancer has increasing clinical interest. However, it been infrequently measured underwent surgery. <b>Objective:</b> We aimed to investigate a trend and predictive factors perioperative PA <b>Methods:</b> This prospective observational study assessed 26 thoracoscopic resection for after completion pulmonary rehabilitation outpatient follow-up program. was as number steps (steps/day) moderate intensity...