Yasuhiro Nakashima

ORCID: 0000-0002-9317-7264
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Cardiac Imaging and Diagnostics
  • Lung Cancer Diagnosis and Treatment
  • Medical Imaging and Pathology Studies
  • Cancer Diagnosis and Treatment
  • Occupational and environmental lung diseases
  • Tracheal and airway disorders
  • Pancreatitis Pathology and Treatment
  • Medical Imaging Techniques and Applications
  • Pericarditis and Cardiac Tamponade
  • Pleural and Pulmonary Diseases
  • Enzyme Production and Characterization
  • Heart Rate Variability and Autonomic Control
  • Cardiac electrophysiology and arrhythmias
  • Acute Myeloid Leukemia Research
  • Immune cells in cancer
  • Hemoglobinopathies and Related Disorders
  • Lung Cancer Treatments and Mutations
  • Tumors and Oncological Cases
  • Intensive Care Unit Cognitive Disorders
  • Vascular Tumors and Angiosarcomas
  • Atomic and Subatomic Physics Research
  • Gastrointestinal disorders and treatments
  • Anesthesia and Neurotoxicity Research
  • Radiopharmaceutical Chemistry and Applications
  • Neuroendocrine Tumor Research Advances

Osaka Metropolitan University
2024-2025

Osaka City University Hospital
2025

Tokyo Medical and Dental University
2015-2024

Tokyo Medical and Dental University Hospital
2015-2021

Japanese Foundation For Cancer Research
2017-2020

The Cancer Institute Hospital
2018-2020

Tokyo Yamate Medical Center
2018

Musashino Red Cross Hospital
2016-2017

National Hospital Organization
2016

Kyoto University Hospital
2016

A review of the literature reflects numerous instances acute pancreatitis developing in patients while being treated with drugs. The causative relation is not yet definitively established but, several instances, there appears to be a probable relation. records at least 112 drug-induced pancreatitis. Fifty-one were caused by steroids or adrenocorticotropic hormone, six estrogen, two azathioprine, 16 diurectics, hypercalcemia, 24 chemotherapy, three clonidine and phenformin, warfarin one each...

10.31838/ijpr/2021.13.01.128 article EN International Journal of Pharmaceutical Research 2020-12-02

Background: Patients with lower-risk myelodysplastic syndromes (MDS) may experience anemia and a high transfusion burden, alongside risk of progression to acute myeloid leukemia. Luspatercept, recombinant fusion protein that acts as an erythroid maturation agent, was FDA/EMA-approved in 2020 based on the phase III MEDALIST trial. There remains unmet need for treatment Asian patients whom red blood cell (RBC) is standard care, rates/severity serum erythropoietin levels are often higher versus...

10.1177/20406207251321715 article EN cc-by-nc Therapeutic Advances in Hematology 2025-01-01

CSF1R-expressing tumor-associated macrophages (TAMs) induce a tumor-promoting microenvironment by regulating immunity. Evidence demonstrates that the expression and single nucleotide polymorphisms of CSF1R relate with survival risk lung cancer in never smokers. However, no previous studies have examined association TAMs mortality or whether prognostic differs according to smoking status adenocarcinoma. Quantitative phosphor-integrated dot staining was used precisely assess TAMs. Using 195...

10.3390/cancers10080252 article EN Cancers 2018-07-31

A surgical case of pulmonary metastases polymorphous low grade adenocarcinoma (PLGA) originating from the minor salivary gland in soft palate a 62-year-old woman is reported. PLGA has been to be locally invasive carcinoma without distant metastases; thus our first reported with histologically-proven lung. We emphasise that attention should paid especially lung even PLGA.

10.1055/s-2007-1013795 article EN The Thoracic and Cardiovascular Surgeon 1995-06-01

Pulmonary epithelial-myoepithelial carcinoma (P-EMC) is a rare subset of salivary gland-type tumors the lung. Because its rarity and unproven malignant potential, optimal therapy for P-EMC has not been defined. Here, we report typical case review literature to consider appropriate treatment. A 54-year-old woman presented with an abnormal lung shadow on routine chest X-ray. computed tomography (CT) scan verified 18-mm endobronchial nodule middle lobe. We performed bronchoscopic biopsy,...

10.1186/s40792-018-0482-8 article EN cc-by Surgical Case Reports 2018-07-09

Abstract Background Due to advances in video-assisted thoracic surgery (VATS), the majority of lung resections can be performed safely via VATS with low morbidity and mortality. However, pulmonary artery (PA) bleeding often requires emergency conversion thoracotomy, potentially leading a life-threatening situation. We report case injury caused by an unexpected stapler-tissue interaction during uniportal lobectomy, highlighting importance recognizing managing such rare complications improve...

10.1186/s40792-024-02048-9 article EN cc-by Surgical Case Reports 2024-10-28

The short-term efficacy of virtual-assisted lung mapping (VAL-MAP), a preoperative bronchoscopic multi-spot lung-marking technique, has been confirmed in 2 prospective multicentre studies. objectives this study were to analyse the local recurrence and survival patients enrolled these studies, long-term.Of 663 559 patients' follow-up data collected. After excluding those who did not undergo VAL-MAP, whose resection was for curative intent, underwent concurrent without or eventually lobectomy...

10.1093/ejcts/ezab421 article EN European Journal of Cardio-Thoracic Surgery 2021-10-07

Natural killer (NK) cells possess spontaneous cytotoxicity against tumors and virus-infected to play a major role in immunosurveillance defense the development of cancer, as well bacterial viral infections. The plasma lipoproteins atherogenesis is recognized, but physiological relevance their immunoregulatory properties still questioned. In particular, it unknown whether hypercholesterolemia should be considered risk factor for diminished immunity old age.To evaluate effects lipoprotein...

10.1093/gerona/58.6.m561 article EN The Journals of Gerontology Series A 2003-06-01

The aim of the present study was to evaluate whether necrosis right bundle branch is responsible for development block in acute myocardial infarction. Twenty patients with anteroseptal infarction were studied--10 (group A) and 10 without B)--to by serial sectioning pathological extent surrounding also that necrosis. Myocardial reached more than 8 mm above moderator band all group A, whereas less 3 only three B. Nine hearts A showed significant branch. In B one case transient no found....

10.1136/hrt.65.6.317 article EN Heart 1991-06-01

is a strong tumor suppressor gene; its deactivation contributes to carcinogenesis and influences clinical outcomes. However, the prognostic influence of p53 on early relapse in patients with surgically resected non-small cell lung cancer remains unclear.

10.1016/j.xjon.2024.06.005 article EN cc-by-nc-nd JTCVS Open 2024-06-01

Abstract Luspatercept has shown durable clinical efficacy for the treatment of anemia in transfusion-dependent patients with lower-risk myelodysplastic syndromes (LR-MDS). We report results a prespecified primary analysis phase 2 trial luspatercept non-transfusion-dependent (NTD) Japanese due to LR-MDS. (starting dose 1.0 mg/kg) was administered subcutaneously once every 3 weeks. The endpoint proportion who achieved hematological improvement-erythroid (HI-E) response (≥ 1.5 g/dL increase...

10.1007/s12185-024-03872-3 article EN cc-by International Journal of Hematology 2024-11-21

A 27-year-old woman presented with a history of gastrointestinal bleeding. Her medical was otherwise unremarkable. Esophagogastroduodenoscopy and colonoscopy the terminal ileum were carried out after an episode bleeding, but source bleeding remained unidentified. Double-balloon endoscopy small intestine [1] then conducted via anal approach. Examination distal disclosed diverticulum ulceration at about 50 cm proximal to ileocecal valve (Figure [1]). Radiography showed 6 long in [2]). Biopsy...

10.1055/s-2006-944646 article EN Endoscopy 2007-12-01

Investigations have been carried out to determine the absorbed dose in air of photons generated from secondary cosmic radiation at sea level Nagoya, Japan. To isolate contribution photons, pulse-height distributions due µ particles and electrons were eliminated observed distribution a measurement with 3" diam. spherical NaI(Tl) detector. The pulse height was inferred coincidence technique using two types scintillation detectors different sensitivities photons. obtain photon fluence rate for...

10.1093/oxfordjournals.rpd.a082595 article EN Radiation Protection Dosimetry 1995-01-01
Coming Soon ...