A5091644390- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Gastroesophageal reflux and treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal Cancer Research and Treatment
- Genetic factors in colorectal cancer
- Cancer Genomics and Diagnostics
- Biliary and Gastrointestinal Fistulas
- Metastasis and carcinoma case studies
- Liver Disease and Transplantation
- Helicobacter pylori-related gastroenterology studies
- Dysphagia Assessment and Management
- Liver Disease Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Neuroblastoma Research and Treatments
- Pancreatitis Pathology and Treatment
- Ophthalmology and Eye Disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Multiple Myeloma Research and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- GDF15 and Related Biomarkers
Fujitsu (Japan)
2025
Fukushima Medical University
2018-2024
Fukushima Medical University Hospital
2021-2024
Soma Central Hospital
2021-2022
Suzuki (Japan)
2020
Ohta Nishinouchi Hospital
2019
Okayama University
1997
Acute kidney injury (AKI), particularly during cardiac surgery, severely affects patient outcomes, yet current diagnostics using serum creatinine levels delay detection. This study investigates real-time urinary oxygen tension (PuO2) as an alternative early marker and correlates it with renal medullary for potential AKI prediction. We developed a modified 3-way silicone catheter designed more reliable urine collection evaluated its performance in terms of PuO2 measurement accuracy. The...
Abstract Background The prognosis of pancreatic cancer (PC) has been improved by new chemotherapy regimens (combination 5-fluorouracil, oxaliplatin, irinotecan, and leucovorin (FOLFIRINOX) or gemcitabine plus nab-paclitaxel (GnP)). Unfortunately, chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse event these two regimens. efficacy pregabalin for CIPN reported in previous studies. However, the mirogabalin remains unknown. Thus, this study, we aimed to clarify which drug...
Abstract Background The efficacy of immune checkpoint blockade in the treatment microsatellite instability (MSI)-high tumors was recently reported. Therefore, acquisition histological specimens is desired cases unresectable solid pancreatic lesions (UR SPLs). This study investigated endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) using a Franseen needle for UR SPL tissue and MSI evaluation. Methods A total 195 patients who underwent EUS-guided aspiration (EUS-FNA) or EUS-FNB...
Immune checkpoint blockade has recently been reported to be effective in treating microsatellite instability (MSI)-high tumors. Therefore, sufficient sampling of histological specimens is necessary cases unresectable pancreatic cancer (UR-PC). This multicenter study investigated the efficacy endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) using a Franseen needle for MSI evaluation patients with UR-PC.A total 89 UR-PC who underwent aspiration (EUS-FNA) or EUS-FNB 22-G needles at...
The sample adequacy and diagnostic accuracy of an endoscopic ultrasound (EUS)-guided fine-needle aspiration (EUS-FNA) for gastric subepithelial lesions (SELs) have been reported to be imperfect. To resolve these issues, a fork-tip needle as EUS-guided biopsy (FNB) has developed. This study was conducted evaluate the usefulness in EUS-FNB SELs. Seventy-nine patients who received EUS-FNA or FNB using SELs were included study. compared between with group (fork-tip group, n = 13) FNA (FNA 66)....
Pancreatic jejunostomy stricture (PJS) is one of the major late complications after pancreaticoduodenectomy. Endoscopic ultrasound-guided pancreatic drainage (EUS-PD) considered a salvage treatment for symptomatic PJS endoscopic retrograde pancreatography failure; however, technical success rate remains unsatisfactory, mainly due to surgically altered anatomy. Herein, we describe case successfully treated with transjejunal EUS-PD using forward-viewing echoendoscope. A 62-year-old man who...
Abstract Endoscopic submucosal dissection (ESD) has become the standard treatment for superficial esophageal squamous cell carcinoma (SESCC). However, strategy SESCC complicated by varices (EVs) not been established. We report two cases of in patients with alcoholic cirrhosis EVs who underwent ESD. Case 1 presented on anal side SESCC, and endoscopic variceal ligation (EVL) was performed before After EVL, successfully treated ESD without any adverse events. 2 from to submucosa just below...
Background and Aim. A wet suction technique (“wet” technique) has been developed to improve the quality of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for sampling various solid lesions. However, no studies have reported on EUS-FNA gastrointestinal (GI) subepithelial lesions (SELs). We conducted a pilot randomized crossover trial explore whether could be useful with regard tissue adequacy upper GI-SELs (UGI-SELs) compared conventional (“dry” technique). Methods. Twenty-six...
Endoscopic resection is a treatment of choice for metachronous early-stage esophageal squamous cell carcinoma (ESCC) appearing after radical cure cancer by chemoradiotherapy (CRT). However, non-curative resection, and procedural complications including perforation due to radiation-induced submucosal fibrosis, are concern. This study aimed evaluate the association between fibrosis usefulness safety endoscopic dissection (ESD) in ESCC CRT. retrospectively analyzed 13 lesions 11 patients our...
Bilio-duodenal bleeding, such as post-endoscopic sphincterotomy (EST) common bile duct (CBD) bleeding after endoscopic retrograde cholangiopancreatography (ERCP), and duodenal due to malignant tumour invasion, can sometimes become severe. Six cases of refractory bilio-duodenal were stanched via covered self-expandable metallic stent (CSEMS) insertion, even though three the patients had a history gastrectomy. The dumbbell-shaped CSEMS was useful for managing post-EST bleeding. Additional...
<b><i>Introduction:</i></b> Sodium hyaluronate (SH) is a useful submucosal injectant for gastric endoscopic dissection (ESD). On the other hand, sodium carboxymethylcellulose (SCMC), which has high viscosity, also been applied clinically. We evaluated efficacy of SCMC compared to that SH in ESD. <b><i>Methods:</i></b> A prospective randomized controlled trial was conducted assess 1.0% as (SCMC group) 0.4% (SH ESD neoplasms. The primary end...
Although the importance of endoscopic ultrasound (EUS) for esophageal varices (EVs) has been demonstrated, it is difficult to obtain sufficient EUS images with water-filling method because poor water stagnation in esophagus. In this study on EVs, we aimed evaluate usefulness jelly-filling EUS. Consecutive patients who underwent EVs were included. The quality images, diagnostic ability presence blood vessels inside and outside wall, procedure time compared between methods. Thirty cases...
Abstract Treatment guidelines for esophageal squamous cell carcinoma (ESCC) with concomitant varices (EVs), which increase the risk of bleeding, are unavailable. A 66‐year‐old man a history total gastrectomy was admitted to hospital owing hematemesis. Emergency upper gastrointestinal endoscopy revealed variceal bleeding near anastomosis between esophagus and jejunum, endoscopic clipping stopped bleeding. Upper following hemostasis four EVs two‐thirds ESCC circumference. The depth suspected...
Abstract Background If the depth of gallbladder malignant tumor (GBMT) invasion is deeper than subserosa (ss), cholecystectomy insufficient. In past reports that used endoscopic ultrasonography (EUS) to diagnose invasion, it was difficult GMBT in ss without a narrow or disrupted lateral hyperechoic layer (LHEL). Therefore, we developed simple preoperative method GBMTs with invasion. Methods Forty-nine GBMT patients who underwent both EUS and surgery were enrolled: 15 whose tumors invaded...
Pancreaticobiliary cancer (PB Ca) is a lethal disease, and useful diagnostic marker urgently needed. A correlation between the human microbiota malignant gastrointestinal diseases was recently reported.To investigate efficacy of duodenal for diagnosing PB Ca.We recruited 22 patients with benign pancreaticobiliary (benign group) 12 Ca (malignant group). The each patient analyzed by 16S rDNA terminal restriction fragment length polymorphism method. Patient characteristics, tumor markers,...
Abstract Objective Iodine staining on white light imaging (WLI) is the gold standard for detecting and demarcating esophageal squamous cell carcinoma (ESCC). We examined effects of texture color enhancement (TXI) improving endoscopic visibility ESCC under iodine staining. Methods Twenty lesions that underwent submucosal dissection were retrospectively included. The difference between surrounding mucosa ( ΔE e) WLI, TXI, narrow‐band was assessed, e 1% WLI TXI. Furthermore, grade determined by...