A5008775897- HIV/AIDS Research and Interventions
- Viral gastroenteritis research and epidemiology
- Child Nutrition and Feeding Issues
- Leptospirosis research and findings
- HIV/AIDS drug development and treatment
- Asthma and respiratory diseases
- Mycobacterium research and diagnosis
- SARS-CoV-2 detection and testing
- Musculoskeletal pain and rehabilitation
- Invertebrate Immune Response Mechanisms
- Tryptophan and brain disorders
- Healthcare during COVID-19 Pandemic
- Tuberculosis Research and Epidemiology
- Obesity, Physical Activity, Diet
- Trypanosoma species research and implications
- Occupational Health and Burnout
- Youth, Drugs, and Violence
- Environmental and biological studies
- Healthcare Regulation
- HIV Research and Treatment
- SARS-CoV-2 and COVID-19 Research
- Health, Nursing, Elderly Care
- Studies on Chitinases and Chitosanases
- Myofascial pain diagnosis and treatment
- Maternal and Neonatal Healthcare
Universidade do Sul de Santa Catarina
2017-2024
Universidade Federal de Santa Catarina
2009-2022
Secretaria da Saúde
2021-2022
University of California, Irvine
2013
UConn Health
2013
Anopheles darlingi is the principal neotropical malaria vector, responsible for more than a million cases of per year on American continent. diverged from African and Asian vectors ∼100 years ago (mya) successfully adapted to New World environment. Here we present an annotated reference A. genome, sequenced wild population males females collected in Brazilian Amazon. A total 10 481 predicted protein-coding genes were annotated, 72% which have their closest counterpart gambiae 21% highest...
Sewage sludge and treated wastewater when contaminated with enteric virus discharged into the environment, could pose a human health risk. The aim of study was to verify presence viability viruses in sewage at local plant Florianopolis city, Brazil. concentrated by organic flocculation polyethylene glycol precipitation electronegative membrane filtration ultrafiltration Centriprep Concentrator. Adenovirus (AdV), hepatitis A (HAV), Rotavirus (RV) were examined for all samples 12 months...
The western mesoregion of the state Santa Catarina (SC), Southern Brazil, was heavily affected as a whole by COVID-19 pandemic in early 2021. This study aimed to evaluate dynamics SARS-CoV-2 virus spreading patterns SC from March 2020 April 2021 using genomic surveillance. During this period, there were 23 distinct variants, including Beta and Gamma, among which Gamma related lineages predominant second wave within SC. A regionalization P.1-like-II Western region observed, concomitant...
The objective of the study is to analyze temporal trend leptospirosis incidence, according rainfall levels in Santa Catarina, seasonality, from 2005 2015. This an ecological time series, with date leptospirosis, and population. incidence rates relative excess Pearson's correlation coefficient (r) angular (β) were analyzed linear regression adjustment, a 5% significance level. Distribution cases, cases reason/rainfall levels, stratified by month occurrence presented. There 5,274 monthly...
Abstract Objective: To evaluate the involvement of nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome in schizophrenia-like behaviour young animals exposed to maternal immune activation (MIA). Methods: this aim, on 15th gestational day, females received an injection lipopolysaccharides. When completed 7, 14 and 45 postnatal days, they were killed whole brain was dissected for biochemical analysis. Animals with days submitted behavioural tests locomotor activity, social...
The aim of this study was to compare two nucleic acid extraction methods for the recovery enteric viruses from activated sludge.Test samples were inoculated with human adenovirus (AdV), hepatitis A virus (HAV), poliovirus (PV) and rotavirus (RV) then processed by an adsorption-elution-precipitation method.Two used: organic solvent-based method a silica method.The organic-based able recoup 20% AdV, 90% RV 100% both PV HAV seeded samples.The 1.8% AdV RV.These results indicate that is more...
Proinflammatory cytokines are critical mediators that control Mycobacterium tuberculosis (Mtb) growth during active (ATB). To further inhibit bacterial proliferation in diseased individuals, drug inhibitors of cell wall synthesis such as isoniazid (INH) employed. However, whether INH presents an indirect effect on by regulating host ATB is not well known. examine this hypothesis, we used vitro human granuloma system generated with primary leukocytes from healthy donors adapted to model ATB....
BACKGROUND AND OBJECTIVES: Musculoskeletal disorder is characterized by changes in neuromuscular, tendinous and joint functions that impact the functionality of affected areas, especially with pain. The intervention reflexotherapy a non-invasive alternative allows instant control acute occupational low back objective this study was to describe results foot reflexology relief pain related nursing staff job. METHODS: Double-blind controlled clinical trial. Thirty-six effective participants...
Santa Catarina is a Brazilian State that has reported the lowest prevalence of human T-cell lymphotropic viruses (HTLV-1/2) in blood donors (0.04%). Although it presents ports, airports and roads facilitate entrance dissemination new infectious agents, no information exists concerning HTLV-1/2 infections HIV/AIDS patients. This study searched for antibodies plasma samples 625 patients from municipality Tubarao (Southern Catarina), disclosed 1.1% positivity (0.48% HTLV-1, 0.48% HTLV-2 0.16%...
This study aimed to evaluate the potential adverse effects of dermal administration Dillenia indica Linnaeus (D. indica) fruit extract in healthy rodents; was standardized betulinic acid. In initial phase, acute were evaluated on skin application site a single dose. A irritation test performed male Wistar rats (n = 8/group) receiving (50-150 mg/mL) with acid (0.5-1.5%, respectively). photosensitivity BALB/c mice 6/group) (150 mg/mL). Afterwards, other 20, male:female, 1:1) used assess...
The identification of mycobacteria is essential because tuberculosis (TB) and mycobacteriosis are clinically indistinguishable require different therapeutic regimens. traditional phenotypic method time consuming may last up to 60 days. Indeed, rapid, affordable, specific easy-to-perform methods needed. We have previously described a polymerase chain reaction-based called mobility shift assay (MMSA) that was designed for Mycobacterium complex (MTC) nontuberculous (NTM) species identification....
To determine the maternal and early childhood factors associated with asthma obesity in children aged 6 to 7 years.A case-control study conducted years. Applications questions about symptoms last 12 months, data first 2 years of life, anthropometric were collected. Children who presented considered as cases those without controls, later divided into two subgroups that eutrophic or overweight/obesity. Logistic regression was performed estimate association between (adequate weight...
BACKGROUND AND OBJECTIVES:Lower back pain is one of the musculoskeletal diseases with highest incidence all over world.In approximately 85% cases it classified as unspecified, which means that has no evident cause.With in mind, geotherapy a non-invasive technique allows control lower pain.The goal this study was to evaluate results on relief unspecified pain.METHODS: Semi-experimental quantitative clinical trial, comparing before and after states, including 26 participants who received four...
Microsatellite markers were developed for Dicksonia sellowiana (Dicksoniaceae), an overexploited and endangered tree-fern species native to Brazil. From enriched genomic library, 11 primer pairs selected used characterize 36 D. individuals from six Brazilian populations. Eight amplified dinucleotide hexanucleotide repeats with two ten alleles per locus; three monomorphic. For the set of polymorphic markers, mean observed expected heterozygosity ranged 0.29 0.44 0.27 0.56, respectively. also...
Introduction: Therapeutic measures have been successful in increasing survival rates and quality of life HIV/AIDS-infected people. However, some people fail to respond antiretroviral therapy (HAART) because viral resistance-associated mutations. Objective: To identify virus genotype the presence mutations that alter susceptibility HAART, factors associated with occurrence these Methods: A cross-sectional study was conducted on adults living HIV attending a specialized outpatient clinic...
Studies have shown the relationship between neuroinflammation and depressive- like parameters. However, research still has not been carried out to evaluate in neonatal period psychiatric disorders adulthood.To verify association immune activation depressive-like parameters adulthood using an animal model.Two days old C57BL/6 animals were exposed lipopolysaccharides (LPS) or phosphate- buffered saline (PBS). When 46 old, they received PBS Imipramine at 14 days. At 60 days, consumption of...
Human immunodeficiency virus (HIV) infection, the etiological agent of acquired syndrome (AIDS), is a serious public health issue. Therapeutic measures have been successful in increasing survival and improving quality life. However, some treatment-naive subjects living with HIV present resistance-associated mutations as result late diagnosis and/or mutant strain infections. The objective this study was to identify genotype assess antiretroviral resistance profile based on results genotyping...
Introdução: Cada vez mais refeições são realizadas fora do ambiente domiciliar, portanto é importante o cuidado com binômio tempo e temperatura dos alimentos, pois estes precisam ser muito bem controlados, a fim de evitar crescimento microbiano possa se fornecer um alimento seguro seus comensais. O objetivo deste estudo foi avaliar os tempos exposição as temperaturas distribuição das preparações quentes servidas no almoço funcionários da uma Unidade Alimentação Nutrição Hospitalar, visando à...
Objetivo: comparar os efeitos da auriculoterapia e reflexoterapia podal para lombalgia aguda inespecífica em docentes discentes universitários área saúde. Método: ensaio clínico, randomizado, controlado, duplo-cego, com 189 participantes distribuídos três grupos: experimental, experimental combinadas. Fora realizados 3 intervenções. Para a coleta foram utilizados: Questionário Sociodemográfico; Escala Visual Analógica de intensidade na avaliação dor; Lombalgia. Os dados analisados no...