A5085499300- SARS-CoV-2 and COVID-19 Research
- Coccidia and coccidiosis research
- Antibiotic Resistance in Bacteria
- Animal Nutrition and Physiology
- SARS-CoV-2 detection and testing
- Viral gastroenteritis research and epidemiology
- Rabbits: Nutrition, Reproduction, Health
- Trypanosoma species research and implications
- Respiratory viral infections research
- Salmonella and Campylobacter epidemiology
- Parasitic Infections and Diagnostics
- Pharmaceutical and Antibiotic Environmental Impacts
- Advanced Proteomics Techniques and Applications
- Mosquito-borne diseases and control
- Genomics and Phylogenetic Studies
- Machine Learning in Bioinformatics
- Bacteriophages and microbial interactions
- Helminth infection and control
- Bee Products Chemical Analysis
- Diet and metabolism studies
- Long-Term Effects of COVID-19
- Animal Behavior and Welfare Studies
- Biochemical and Molecular Research
- Escherichia coli research studies
- Monoclonal and Polyclonal Antibodies Research
Universidade Federal de Santa Catarina
2021-2025
Antimicrobial resistance (AMR) poses a significant threat to global public health. The One Health approach, which integrates human, animal, and environmental health, highlights the roles of agricultural hospital settings in propagation AMR. This study aimed analyze resistome gut microbiome composition individuals from high-intensity animal husbandry area western region Santa Catarina, Southern Brazil, who were subsequently admitted University Hospital city Florianopolis, located eastern part...
The western mesoregion of the state Santa Catarina (SC), Southern Brazil, was heavily affected as a whole by COVID-19 pandemic in early 2021. This study aimed to evaluate dynamics SARS-CoV-2 virus spreading patterns SC from March 2020 April 2021 using genomic surveillance. During this period, there were 23 distinct variants, including Beta and Gamma, among which Gamma related lineages predominant second wave within SC. A regionalization P.1-like-II Western region observed, concomitant...
Avian pathogenic
SARS-CoV-2 genome surveillance is important for monitoring risk groups and health workers as well data on new cases mortality rate due to COVID-19. We characterized the circulation of variants from May 2021 April 2022 in state Santa Catarina, southern Brazil, evaluated similarity between present population healthcare (HCW). A total 5291 sequenced genomes demonstrated 55 strains four concern (Alpha, Delta, Gamma Omicron—sublineages BA.1 BA.2). The number was relatively low 2021, but deaths...
Colibacillosis is a disease caused by Escherichia coli and remains major concern in poultry production, as it leads to significant economic losses due carcass condemnation clinical symptoms. The development of antimicrobial resistance growing problem worldwide concern. Lysogenic bacteriophages are effective vectors for acquiring disseminating antibiotic genes (ARGs). aim this study was investigate the complete genome isolates from femurs Brazilian broiler chickens order presence associated...
The main purpose of this research was to analyze the relation genetic polymorphisms frequently expressed by antigen-presenting cells, erythrocytes and malaria susceptibility/resistance with human infection cases.The sample used consisted 23 Plasmodium vivax (Pv)-and P. falciparum (Pf)-infected patients, 21 healthy individuals as a control group, from Baixo Amazonas population in Pará, Brazil.The Asp299Gly Toll-like receptor 4 (TLR4), Gly42Asp, Arg89Cys, Ala100Thr, T-33C Duffy gene (FY) were...
Although various tools provide proteomic information, each tool has limitations related to execution platforms, libraries, versions, and data output format. Integrating generated from different software is a laborious process that can prolong analysis time. Here, we present FastProtein, protein pipeline user-friendly, easily installable, outputs important information about subcellular location, transmembrane domains, signal peptide, molecular weight, isoelectric point, hydropathy,...
Over the past four years, angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease (TMPRSS2) have been extensively studied, given their important role in SARS-CoV-2 replication; however, most studies failed to compare behavior face of different genomic variants. Therefore, this study evaluated influence variants ACE2/TMPRSS2 expressional profiles. To achieve this, 160 nasopharyngeal samples, previously detected with via RT-qPCR (June 2020-July 2022), were quantified for...
This study aimed to compare the effects of different levels cashew nutshell liquid (CNSL) and castor oil (CNSL-castor oil) with growth-promoting antibiotics associated anticoccidials in broiler chickens challenged coccidiosis. In this work, 2520 one-day-old male chicks (Cobb) were randomly assigned 84 pens, containing 30 birds each. The experimental design was completely randomized, seven treatments: enramycin (8 ppm), virginiamycin (16.5 tylosin (55 ppm); doses CNSL-castor (0.5, 0.75, 1.00...
Epitopes are portions of a protein that recognized by antibodies. These small amino acid sequences represent significant breakthrough in branch bioinformatics called immunoinformatics. Various software available for linear B-cell epitope (BCE) prediction such as
ABSTRACT Since December 2019, the COVID-19 pandemic caused by SARS-CoV-2 has reached approximately 769 million people, leading to more than 7 deaths worldwide. Faced with possible presence of other respiratory pathogens that could co-infect and modify clinical response patients detected for SARS-CoV-2, some researchers have explored this line investigation. The relationship between these co-infections remains unclear, a need deepen our knowledge about interactions among pathogens, host....
This study aimed to assess the impact of a commercial blend functional oils, specifically cashew nutshell liquid and castor oil (FO), in two physical forms (solid: P; liquid: S), comparison combination virginiamycin anticoccidials on gut health broilers challenged with coccidiosis. A total 1760 1-day-old male chicks were randomly distributed design eight treatments. The treatments included: control group (without additive), OFS_0.75_kg/t (FO spray), OFP_1.0_kg/t powder), OFP_1.5_kg/t Sal...
Abstract Clostridioides difficile BI/NAP1/ribotype 027 is an epidemic hypervirulent strain found worldwide, including in Latin America. We examined the genomes and exoproteomes of two multilocus sequence type (MLST) clade 2 C. strains considered hypervirulent: ICC-45 (ribotype SLO231/UK[CE]821), isolated Brazil, NAP1/027/ST01 (LIBA5756), during a 2010 outbreak Costa Rica. isolates were cultured extracellular proteins analyzed using high-performance liquid chromatography-tandem mass...
Assignment of gene function has been a crucial, laborious, and time-consuming step in genomics. Due to variety sequencing platforms that generates increasing amounts data, manual annotation is no longer feasible. Thus, the need for an integrated, automated pipeline allowing use experimental data towards validation silico prediction utmost relevance. Here, we present computational workflow named AnnotaPipeline integrates distinct software types on proteogenomic approach annotate validate...
Antimicrobial resistance is a major threat to public health. use in animal husbandry concern since it can favor an increase antimicrobial among farms. Herein, we aim better understand and characterize the main resistome profiles microbial communities found pig Sampling of swine manure was performed two different timepoints (October 2019 January 2020) each 14 farms, located mesoregion Western Santa Catarina state Brazil, pole product production worldwide importance. Samples were divided into...
Abstract Background Although various tools provide proteomic information, each has its limitations regarding execution platforms, libraries, versions, and data output format. Therefore, integrating analyses generated using different software programs is a manual process that can prolong the analysis time. Results This paper presents FastProtein, protein pipeline tool developed in Java. user-friendly, easily installable, provides important information subcellular location, transmembrane...
Abstract Background Type 2 diabetes causes over a million deaths annually, ranking in the top ten of death worldwide. Glycemic control through dietary adequacy is essential for treatment success and disease prevention. Recent evidence indicates that glycemic response to various foods varies from individual individual. The intestinal microbiome seen as potential key player, mediating effect on response. By design, however, most published studies cannot separate variation effects (ITE)...
Introdução: Mycoplasma genitalium (MG) é uma bactéria que causa infecções sexualmente transmissíveis (IST), afetam homens e mulheres, com preocupações globais em razão do desenvolvimento de resistência antimicrobiana. No Brasil, há poucas informações sobre antimicrobiana MG. Objetivo: Estudar genes fornecer os primeiros resultados nacionais a MG para macrolídeos fluoroquinolonas. Métodos: Foram utilizadas amostras detectadas obtidas swab uretral masculino vaginal gestantes, coletadas durante...