A5080853315- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Tracheal and airway disorders
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Tissue Engineering and Regenerative Medicine
- Cancer Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Sarcoma Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Research Studies
- Respiratory Support and Mechanisms
- Periodontal Regeneration and Treatments
- Cardiac tumors and thrombi
- Immunotherapy and Immune Responses
- Cancer, Hypoxia, and Metabolism
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Soft tissue tumor case studies
- Congenital Diaphragmatic Hernia Studies
- Infrared Thermography in Medicine
- Radiomics and Machine Learning in Medical Imaging
- Pulmonary Hypertension Research and Treatments
- Occupational and environmental lung diseases
- Salivary Gland Tumors Diagnosis and Treatment
Tenri Hospital
2016-2025
Sumitomo Dainippon Pharma (Japan)
2002-2022
Kagawa University
2004-2015
Kagawa University Hospital
2008
Fukui Red Cross Hospital
2006
Kyoto University
2006
Japanese Red Cross Society Wakayama Medical Center
2006
Kyoto Katsura Hospital
2004
National Kinki Chuo Hospital for Chest Disease
2003
Osaka University
1997
Nutritional status is associated with an effect on oncological outcomes. However, the of nutritional postoperative survival in lung cancer has not been well studied. We retrospectively analysed and evaluated preoperative body mass index (BMI) changes weight outcomes surgery.A total 1311 patients non-small-cell who underwent surgery between January 2001 December 2011 were included this study. Preoperative at 4-12 weeks prior to was obtained 737 ratio change calculated.The classified into four...
Bevacizumab exerts anti-angiogenic effects in cancer patients by inhibiting vascular endothelial growth factor (VEGF). However, its use is still limited due to the development of resistance treatment. Such can be regulated various factors, although underlying mechanisms remain incompletely understood. Here we show that bone marrow-derived fibrocyte-like cells, defined as alpha-1 type I collagen-positive and CXCR4-positive contribute acquired bevacizumab. In mouse models malignant pleural...
Infrared thoracoscopy is a new method of identifying lung intersegmental borders. This study compared the efficacy 2- and 1-wavelength infrared thoracoscopy.A total 30 consecutive patients who underwent segmentectomy were evaluated by these methods (2-wavelength method, 10 patients; 20 patients). We ligated dominant pulmonary artery then observed using an thoracoscope after indocyanine green (ICG) intravenous injection. The 2-wavelength irradiation detection conducted at 940 805 nm,...
Background: The objective of this study was to clarify the clinical features pulmonary cryptococcosis using chest computed tomography (CT) and positron emission with [18F]fluoro-2-deoxy-d-glucose (FDG-PET), a view developing appropriate treatment. Methods: We analyzed features, CT FDG-PET characteristics six cases that were treated by surgery. patients comprised four males two females, ranging in age from 28 79 years. Results: All asymptomatic had no extrapulmonary involvement. In all cases,...
The optimal surgical treatment for non-small cell lung cancer (NSCLC) with vertebral body invasion remains both controversial and challenging. We reviewed our experiences of NSCLC invasion, in which we have performed induction chemoradiotherapy followed by resection en bloc partial vertebrectomy.Six patients underwent an operation following from January 2001 to July 2006. Vertebral was evaluated the chest CT MRI findings. Either carboplatin-paclitaxel (n=3) or carboplatin-docetaxel used. Two...
We investigated whether saber sheath-type tracheomalacia could be treated by the slow release of bone morphogenetic protein (BMP)-2 from a gelatin sponge. A 1 cm gap was made in middle portion each 10 consecutive tracheal cartilage rings canine cervix (control group, n = 3), then sponge containing 12 μg BMP-2 solution implanted (12 3). In another group (120 + P contained 120 solution, and covered with periosteum. All control dogs developed tracheomalacia, whereas not observed groups. fibrous...
We investigated the efficiency of basic fibroblast growth factor (b-FGF) released from a gelatin sponge in regeneration tracheal cartilage. A 1-cm gap was made midventral portion each 10 consecutive cervical cartilages (rings 4 to 13) 15 experimental dogs. In control group (n = 5), resulting left blank. alone implanted gap. b-FGF containing 100 mug solution euthanatized one five dogs at 1 month after implantation and 3 months examined implant sites macroscopically microscopically. groups, no...
Abstract HLA‐transgenic mice have been developed to facilitate studies of HLA‐restricted cytotoxic responses, e.g., for the identification immunodominant CTL epitopes and optimization peptide or DNA vaccine constructs human use. We HLA‐A2402/K b ‐transgenic expressing chimeric (α1 α2 domains HLA‐A2402) mouse (α3, transmembrane cytoplasmic H‐2K ) class I molecules. Immunization these with various known HLA‐A24‐restricted cancer epitope peptides derived from gp100, MAGE‐1, MAGE‐3, Her2/neu,...
Objective: The purpose of this study was to evaluate the accuracy 3′-deoxy-3′-18F-fluorothymidine (FLT) positron emission tomography (PET) for detection lung tumor in comparison with 2-deoxy-2-18F-fluoro-D-glucose (FDG) PET. Methods: Fifty-four patients newly diagnosed pulmonary nodules on chest computed tomographic (CT) scan suggestive a malignant were examined both FLT and FDG intensity uptake tumors scored. For visualized lesions, maximum standardized value (SUV) calculated. Results:...
Our previous studies have demonstrated that slow release of basic fibroblast growth factor (b-FGF) or bone morphogenetic protein 2 (BMP-2) induces cartilage regeneration. In the present study, we investigated whether synchronous b-FGF and BMP-2 would induce more widespread earlier regeneration than induced by each alone. A 1-cm defect was made in mid-ventral portion 10 consecutive tracheal rings. four controls, left untreated. gelatin group (n = 4), empty sponge implanted. + 5), two sponges...
We investigated the efficiency of bone morphogenetic protein (BMP)-2 released slowly from gelatin sponge for tracheal cartilage regeneration. A 1-cm gap was made in mid-ventral portion each 10 consecutive cartilages. In control group (n = 4), resulting left untreated. plain implanted gap. BMP-2 containing 100 microg implanted. euthanatized all dogs at 1, 3, 6, and 12 months after implantation, respectively, then examined implant site macro- microscopically. group, regenerated fibrous newly...
The existence of circulating tumor cells (CTCs) in patients with lung cancer has been reported. purpose this study was to assess whether CTCs are predictive the pathological effects induction chemoradiotherapy for non-small cell cancer. Patients who underwent followed by surgery were compared those alone. Peripheral and pulmonary venous blood samples from involved lobe collected intraoperatively, number counted using CellSearch™ system, an epithelial adhesion molecule-based immunomagnetic...
We compared the effectiveness of 3-dimensional computed tomography pulmonary angiography (3D-CTPA) and thin-section multiplanar reconstruction (MPR) images obtained using contrast-enhanced multidetector row CT (MDCT), in evaluation artery (PA) branches right upper lobe. studied 127 patients suspected having lung cancer lobe who underwent MDCT scans a lobectomy. intraoperative findings PA with 3D-CTPA MPR images. In 125 (97.7%) patients, one or more arose from arteries other than superior...