- Climate Change and Health Impacts
- Thermoregulation and physiological responses
- Drug-Induced Adverse Reactions
- Body Composition Measurement Techniques
- Diagnosis and Treatment of Venous Diseases
- Thermal Regulation in Medicine
- Urticaria and Related Conditions
- Autoimmune Bullous Skin Diseases
- Contact Dermatitis and Allergies
- Robotic Locomotion and Control
- Healthcare and Venom Research
- Building Energy and Comfort Optimization
- Perovskite Materials and Applications
- Smart Grid Energy Management
- Mast cells and histamine
- Cellular Automata and Applications
- Infection Control and Ventilation
- Software System Performance and Reliability
- Food Allergy and Anaphylaxis Research
- Venous Thromboembolism Diagnosis and Management
- Software Testing and Debugging Techniques
- Software Reliability and Analysis Research
- Retinal and Optic Conditions
- Iterative Learning Control Systems
- Reservoir Engineering and Simulation Methods
Fujian Medical University
2018-2025
First Affiliated Hospital of Fujian Medical University
2018-2025
University of Science and Technology of China
2023-2024
Shandong University
2020-2023
Shenzhen Institute of Building Research (China)
2023
Universiti Malaysia Pahang Al-Sultan Abdullah
2023
Beijing Jiaotong University
2018-2022
Qilu Hospital of Shandong University
2020
Molina Center for Energy and the Environment
2020
Fudan University
2018-2019
In the production environment, a large part of microservice failures are related to complex and dynamic interactions runtime environments, such as those multiple instances, environmental configurations, asynchronous microservices. Due complexity dynamism these failures, it is often hard reproduce diagnose them in testing environments. It desirable yet still challenging that can be detected faults located at environment allow developers resolve efficiently. To address this challenge, paper,...
Specific ethnic genetic backgrounds are associated with the risk of Stevens–Johnson syndrome / toxic epidermal necrolysis (SJS/TEN) especially in Asians. However, there have been no large cohort, multiple‐country epidemiological studies medication related to SJS/TEN Asian populations. Thus, we analyzed registration databases from multiple countries who were treated during 1998–2017. A total 1,028 cases identified algorithm drug causality for necrolysis. Furthermore, those medications labeled...
Anticancer drugs have revolutionized tumor therapy, with cutaneous toxicities such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) being common immune-related adverse events. The debate over the efficacy of systemic corticosteroids in treating these conditions persists, while necrosis factor (TNF)-alpha inhibitors show promise. This study aims to evaluate effectiveness safety combination therapy involving TNF-α inhibitor adalimumab for SJS/TEN induced by anticancer...
Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are life-threatening disease. However, there only few epidemiologic studies of SJS/TEN from China. To analyze the clinical characteristics, causality, outcome treatment for in China, we reviewed case reports patients with China National Knowledge Infrastructure (CNKI) Wanfang database 2006 to 2016 who were admitted First Affiliated Hospital Fujian Medical University during same period. There 166 enrolled, including 70 SJS, 2...
Debugging microservice systems involves the deployment and manipulation of on a containerized environment faces unique challenges due to high complexity dynamism microservices. To address these challenges, in this paper, we propose debugging approach for based delta algorithm, which is minimize failureinducing deltas circumstances (e.g., deployment, environmental configurations) effective debugging. Our includes novel techniques defining, deploying/manipulating, executing following idea In...
Objective In this study we aimed to compare the efficacy and safety of two personalized rescue therapies for Helicobacter pylori infection. Methods An open‐label, single‐center, randomized controlled trial was conducted. Patients who had failed one or regimens H. infection were receive a 14‐day bismuth‐containing quadruple therapy guided by antimicrobial susceptibility testing (AST) personal medication history (PMH). AST group, either amoxicillin, clarithromycin, metronidazole levofloxacin...
Acute generalized exanthematous pustulosis is a severe, usually drug-related reaction, characterized by an acute onset of mainly small non-follicular pustules on erythematous base. Most cases (AGEP) clear quickly with systemic corticosteroid, but severe or recalcitrant may need other therapies. In this case, man in his 40 s history psoriasis consulted physician about widespread erythema, pustules, target lesions, and fever after the administration quadruple antituberculosis drug. Routine...
Abstract Toxic epidermal necrolysis (TEN) is a fatal drug-induced skin reaction and an emerging public health issue. Triggered by common medications, TEN patients undergo severe sudden detachment caused keratinocyte cell death. Although molecular mechanisms driving death have been proposed, the main drivers remain unknown no effective therapy exists. To systematically map changes that are associated with identify potential druggable targets, we employed single- spatial proteomics technique...
The transport management mode fundamentally determines the sustainable development of high-speed rail passenger (HSRPT), which was shocked by COVID-19 pandemic in 2020. In order to study mechanism HSRPT and impact COVID-19, primarily based on data from Beijing–Shanghai (HSR) taken 2018, we adopt system dynamics (SD) provide a scenario simulation method examination operation status under entrusted transportation (ETMM) VENSIM, take into account following two evaluation indicators: economic...
Bipedal humanoid robot has the ability to both move and manipulate in complex environments, which is of great significance future. However, stable bipedal walking real world always been a challenge industry even academia. The traditional model-based methods are highly dependent on environment, with high modeling complexity lack generalization. solution based simplified model usually causes problem that control algorithms cannot adapt terrain environment. This paper presents newly designed...
With the aim to train innovative talents for nation, we propose "Practice Course of Engineering Project" in biomedical engineering cultivate students' ability.In order ensure purpose innovation ability training, a series specific measures are put forward such as strict project selection, reasonable arrangement, optimization curriculum, improvement teaching idea, strengthening supervision and evaluation, etc. Project practice is conducive cultivating functional practical ability.Bring into...
Objective Guide the reader to actively use network of medical resources and improve access information ability play a social educational function library. Methods Record readers’ electronic reading room in library behavior by management software analyze data using statistical methods. Results Various types readers at different times, uses time periods is also behavior, learning, entertainment no difference allocation utilization leisure e-commerce there significant day...
<title>Abstract</title> Identification of contaminant sources in rivers is crucial to river protection and emergency response. A general Bayesian framework combining the forward transport model with observed data proposed identify unknown pollutions this paper. The computational effectiveness inference will be significantly influenced by efficiency accuracy model. Therefore, a cellular automata (CA) developed efficiently simulates concentration values pollutant estimation. These simulated...