A5030989801- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Moyamoya disease diagnosis and treatment
- Acute Ischemic Stroke Management
- Neurological Complications and Syndromes
- Vascular Malformations Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Metastasis and carcinoma case studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiac Imaging and Diagnostics
- Ophthalmology and Eye Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Lung Cancer Diagnosis and Treatment
- Aortic Disease and Treatment Approaches
- Lung Cancer Treatments and Mutations
- Cerebral Venous Sinus Thrombosis
- Neurofibromatosis and Schwannoma Cases
- Coronary Interventions and Diagnostics
- Cancer Genomics and Diagnostics
- Cerebrospinal fluid and hydrocephalus
- Neuroendocrine Tumor Research Advances
- Sexual Differentiation and Disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Advanced Breast Cancer Therapies
- Breast Cancer Treatment Studies
Shanghai Jiao Tong University
2025
Jilin University
2012-2024
First Bethune Hospital of Jilin University
2011-2024
Union Hospital
2012-2024
Peking Union Medical College Hospital
2020-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2024
Qilu Hospital of Shandong University
2024
Wenzhou Medical University
2023
Gaozhou People's Hospital
2021-2023
University of Missouri Health System
2023
Macrophage inhibitory cytokine 1 (MIC-1/GDF15) has been identified as a potential novel biomarker for detection of pancreatic cancer (PCa). However, the diagnostic value serum MIC-1 ductal adenocarcinoma (PDAC), particularly those at early stage, and treatment response monitoring have not yet investigated. expression in tumor tissue was analyzed by RT-PCR from 64 patients with PDAC. Serum levels were detected ELISA 1472 participants including PDAC, benign pancreas tumor, chronic pancreatitis...
To investigate the efficacy and safety of pyrotinib in treating patients with human epidermal growth factor receptor type 2 (HER2)-positive breast cancers brain metastasis.This is a multicenter retrospective study, HER2-positive cancer metastasis were studied. The enrolled given 400 mg orally once per day for 21 days as one cycle, evaluated every two cycles. All relevant data detected final assessments including medical history, clinical examination, histopathology, immunohistochemistry,...
Abstract Background Significant controversy remains regarding the care of patients with clinical stage III (N2-positive) NSCLC. Although multimodality therapy is effective, roles surgery, chemotherapy, and radiotherapy are not fully defined optimal treatment approach firmly established. We analyzed outcomes predictors associated trimodality (TT) in National Cancer Database. Materials Methods The NCDB was queried from 2004 to 2014 for NSCLC diagnosed (N2) disease treated chemotherapy...
Early cerebral infarction (ECI) following aneurysmal subarachnoid hemorrhage (aSAH) remains poorly understood. This study aims to determine the frequency and risk factors of this special episode, as well assess relationship between its patterns outcome. We retrospectively enrolled 243 patients who underwent aneurysm treatment within 60 hours SAH. ECI was defined one or more new hypodense abnormalities on computed tomography 3 days after SAH, rather than lesions attributable edema, retraction...
<b>SUMMARY:</b> Although neurofibromatosis type 1 (NF-1) is commonly considered neurocutaneous, severe arterial and venous abnormalities have been noted. Our patient, a 28-year-old woman, had bilateral giant extracranial aneurysms of the internal carotid arteries as well skull base meningoceles involving jugular foramina aberrant veins. CT MR imaging, digital subtraction and/or other angiography techniques, may be required to clarify pathology in patients with suggested vascular lesions.
Abstract Increasing evidences reported that cancer‐triggered inflammation was associated with survival prognosis from colorectal cancer ( CRC ). However, the comprehensive effects of inflammatory‐based co NLR ‐ PLR combines neutrophil‐to‐lymphocyte ratio ) and platelet‐to‐lymphocyte rarely remain to be determined during chemotherapy. We retrospectively analyzed clinical data baseline laboratory parameters 153 patients who underwent palliative adjuvant chemotherapy between January 2009 2012....
Objective This study utilized computed tomography angiography (CTA) to assess the risk of acute type A aortic dissection (ATAAD) by analyzing imaging morphology indicators ascending aorta, along with relevant factors associated dissection. Methods The a retrospective observational research design. population consisted 172 patients who received treatment in Department Cardiothoracic Surgery at Qilu Hospital, Shandong University, from January 2018 December 2022. were divided into two groups:...
Persistent hypoglossal artery (PHA), a rare embryological carotid-basilar anastomosis, is usually accompanied by hypoplastic vertebral and posterior communicating arteries, thereby such vascular anomaly serves as the main feeder supplying vertebrobasilar territory. Although rarely reported, simultaneous anterior territory infarcts related to PHA carotid atherosclerosis can occur. To date, far we know, only 4 cases have been previously reported in literature. Here, present case of 65-year-old...
Introduction: Spontaneous cerebrospinal fluid leakage is usually caused by developmental abnormalities and rare, accounting for approximately 5% of the cases (CSF) leakage.[1] To best our knowledge, clival dysplasia-caused CSF rhinorrhea has never been reported in neurosurgical field. Conclusion: often treated surgery, a transsphenoidal approach repair main surgical method used, offering advantages less trauma, fewer complications, rapid postoperative recovery, low recurrence rate.
A 55-year-old male presented with fever, stupor, aphasia, and left hemiparesis. history of head trauma 3 months before was also reported. Cranial magnetic resonance imaging revealed slight contrast enhancement lesions under the right frontal skull plate lobe. Because deterioration in nutritional status intracranial hypertension, patient prepared for burr hole surgery. subdural empyema (SDE) recurred after simple drainage. After detection Brucella species SDE, craniotomy combined antibiotic...
Maximum-likelihood methods for solving the consensus sequence identification (CSI) problem on DNA sequences may only find a local optimum rather than global optimum. Additionally, such do not allow logical constraints to be imposed their models. This study develops linear programming technique solve CSI problems by finding an sequence. method is computationally more efficient and guaranteed reach The developed can also extended treat complicated with ambiguous conserved patterns.A first...
Periodic paralysis (PP) is an uncommon inherited disorder causing recurrent episodes of muscle weakness, with incidence 0.001%. Normokalemic periodic (NormoKPP) as the rarest subtype PP contains both familial and sporadic. Familial NormoKPP caused by p.M1592V mutation skeletal sodium channel alpha subunit (SCN4A) gene rarely reported. Only three pedigrees related to mutations in SCN4A have been previously We herein presented a family case associated mutation, which respiratory occurred...
Brown adipose tissue (BAT) is important in monitoring energy homeostasis and cancer cachexia. Different from white tissue, BAT characterized by the presence of a large number mitochondria adipocytes. Translocator protein 18 kDa (TSPO), critical transporter, expressed outer membrane mitochondria. We speculated that [18F]DPA714, specific TSPO tracer, may monitor activity tumor-bearing mice vivo. first analyzed radioactive uptake positron emission tomography (PET) tracers CT26 xenograft with...
A 56-year-old man presented with vertigo of 4 days duration. Neurologic examination was unremarkable. CT angiograms revealed a right internal carotid artery (ICA) stenosis and an ipsilateral proatlantal intersegmental (PIA, type 1). The PIA arose from the ICA, ran upward, then took dorsal course, continued as vertebral artery, serving major contributor posterior circulation (figure, A–C). Catheter-based angiogram showed ICA 60% D). He chose drug therapy remained asymptomatic on follow-up....
A 55-year-old woman underwent FDG PET/CT to evaluate a pancreatic mass. The images showed elevated activity in the uncinated process of pancreas, suggestive malignancy. However, pathological examination from resected lesion demonstrated schwannoma.