A5080251972- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Semiconductor materials and devices
- Advancements in Semiconductor Devices and Circuit Design
- Silicon Carbide Semiconductor Technologies
- Cellular Mechanics and Interactions
- Elasticity and Material Modeling
- Magnesium in Health and Disease
- Advanced NMR Techniques and Applications
- Molecular Sensors and Ion Detection
- Amino Acid Enzymes and Metabolism
- Sensor Technology and Measurement Systems
- Microtubule and mitosis dynamics
- Atomic and Subatomic Physics Research
- Nitric Oxide and Endothelin Effects
- Trace Elements in Health
- Nuclear physics research studies
- Advanced Materials and Mechanics
- Enzyme-mediated dye degradation
- Fungal Biology and Applications
- Bone Tissue Engineering Materials
- Ion channel regulation and function
- Crystallography and Radiation Phenomena
- Spaceflight effects on biology
- Crystal Structures and Properties
Kobe University
2022-2024
Kyoto Sangyo University
2017-2023
Kyoto University
2002-2021
RIKEN Center for Biosystems Dynamics Research
2021
Osaka University
1964-2020
The University of Tokyo
1981-2015
Tokyo University of Science
1974-2014
Santen (Japan)
2010-2013
RIKEN Nishina Center
2012
Kindai University
2010-2011
Recognition of phosphate monoester dianion by an alkoxide-bridged dinuclear zinc(II) complex (Zn2L3+) has been studied (L = alkoxide species 1,3-bis[bis(pyridin-2-ylmethyl)amino]propan-2-ol). Potentiometric pH titration study disclosed a 1 : phenyl complexation with Zn2L3+ in aqueous solution. The dissociation constant (= [Zn2L3+][PhOPO3(2-)]/[Zn2L3+-PhOPO3(2-)]) is extremely small value 2.5 x 10(-8) mol dm(-3) at 25 degrees C I 0.10 (NaNO3). X-ray crystal analysis the dizinc(II)...
The structure of a synthetic iron mica, KFe~+(Fea+Sia)O10(OH)~, determined from visually estimated intensities, shows very slight departure Pabst's idealized biotite structure.The sextuple cell formerly used to describe micas accounts for the observed twinning.
Magnesium is an essential ion for numerous physiological processes. MgtE a Mg2+ selective channel involved in the maintenance of intracellular homeostasis, whose gating regulated by levels. Here, we report that ATP binds to MgtE, regulating its Mg2+-dependent gating. Crystal structures MgtE-ATP complex show CBS domain MgtE. Functional studies support binding enhances affinity within concentrations this divalent cation, enabling function as vivo sensor. dissociation from upregulates influx at...
Immobilized metal ion affinity chromatography (IMAC) is now a widely accepted technique for the separation of natural or artificial products that beginning to find industrial applications. Here, we introduce novel procedure phosphopeptides and phosphorylated proteins by immobilized zinc(II) chromatography. The phosphate-binding site gel an alkoxide-bridged dinuclear complex, 1,3-bis[bis(pyridin-2-ylmethyl)amino]propan-2-olato dizinc(II) complex (Phos-tag), which linked highly cross-linked 4%...
Abstract NarK belongs to the nitrate/nitrite porter (NNP) family in major facilitator superfamily (MFS) and plays a central role nitrate uptake across membrane diverse organisms, including archaea, bacteria, fungi plants. Although previous studies provided insight into overall structure substrate recognition of NarK, its molecular mechanism, driving force for transport, remained elusive. Here we demonstrate that is antiporter, using an vitro reconstituted system. Furthermore, present...
Magnesium is the most abundant divalent cation in living cells and crucial to several biological processes. MgtE a Mg(2+) channel distributed all domains of life that contributes maintenance cellular homeostasis. Here we report high-resolution crystal structures transmembrane domain MgtE, bound Mg(2+), Mn(2+) Ca(2+). The Mg(2+)-bound structure clearly visualized hydrated ion within its selectivity filter. Based on those biochemical analyses, propose mechanism for which geometry hydration...
Ultrahigh-temperature rapid thermal oxidation of 4H-SiC(0001) surfaces in dry O2 ambient was performed at temperatures up to 1700 °C. The temperature dependence the reaction-limited linear growth rate a SiO2 layer revealed that not active but passive is dominant even 1600 °C, and its activation energy estimated be 2.9 eV. We also found high-temperature beneficial improving SiO2/SiC interface properties, unintentional during cooling down process causes degradation. By effectively suppressing...
This paper introduces a simple, rapid, and sensitive procedure for the analysis of phosphorylated compounds (ROPO(3) (2-)) by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS). The method is based on characteristic shift total-charge change (from -2 to +1) phosphate residue due complexation ROPO(3) (2-) with dinuclear zinc(II) complex (1,3-bis[bis(2-pyridinylmethyl)amino]-2-propanolato dizinc(II) complex, Zn(2)L(3+)) in aqueous solution at...
MgtE is a Mg 2+ channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role homeostasis. The previously determined structures the -bound, closed-state, structure-based functional analyses of revealed that binding ions cytoplasmic domain induces inactivation maintain There are no transmembrane (TM) for -free conditions, pore-opening mechanism has thus remained unclear. Here, we cryo-electron microscopy (cryo-EM) structure MgtE-Fab...
Temperature-dependent Hall effect measurements were conducted to investigate the channel conduction mechanisms of 4H-SiC metal-oxide-semiconductor field-effect transistors (MOSFETs). This method allows us discriminate impact density mobile (free) carriers in inversion channels and their net mobility on performance SiC MOSFETs. It was found that, while free carrier ratio MOSFETs with conventional gate oxides formed by dry oxidation is below 4% at 300 K, increasing due thermal excitation...
During morphogenesis in development, multicellular tissues deform by mechanical forces induced spatiotemporally regulated cellular activities, such as cell proliferation and constriction. Various morphologies are formed because of various spatiotemporal combinations sequences activities. Despite its potential to variations, is a surprisingly robust process, which qualitatively similar reproducibly even under fluctuation To understand these essential characteristics tissue morphogenesis,...
To investigate the impact of Al atoms on channel mobility at SiO 2 /SiC interface, we fabricated junctionless metal-oxide-semiconductor field-effect transistors (MOSFETs), in which thin n + -SiC epitaxial layers with and without ion implantation were used as a channel, compared their electrical characteristics. The effective (m eff ) -channel MOSFET doping was estimated to be 14.9 cm /Vs, is higher than inversion-mode same gate oxidation condition (3.1 /Vs). m values MOSFETs low...
Understanding the growth-induced deformation of soft materials in viscous environments is important for a variety problems nature and engineering. Here, we focus on fluid–structure interaction hyperelastic sheet growing an incompressible Newtonian fluid Stokes flow regime. We develop computational framework simulating this problem, where isogeometric boundary integral method used with Kirchhoff–Love shell formulation elastic–plastic decomposition gradient tensor. quantify relative effects...