A5069467534- Lung Cancer Diagnosis and Treatment
- Geophysical and Geoelectrical Methods
- Lung Cancer Treatments and Mutations
- Seismic Imaging and Inversion Techniques
- Geophysical Methods and Applications
- Radiomics and Machine Learning in Medical Imaging
- Radiation Dose and Imaging
- Drilling and Well Engineering
- Pleural and Pulmonary Diseases
- Advanced X-ray and CT Imaging
- Material Properties and Processing
- COVID-19 diagnosis using AI
- NMR spectroscopy and applications
- Trauma Management and Diagnosis
- Digital Radiography and Breast Imaging
- Venous Thromboembolism Diagnosis and Management
- Textile materials and evaluations
- Cancer Treatment and Pharmacology
- Hydraulic Fracturing and Reservoir Analysis
- Ultrasound in Clinical Applications
- Glioma Diagnosis and Treatment
- Natural Fiber Reinforced Composites
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging Techniques and Applications
- Structural Analysis of Composite Materials
Northwestern University
2007-2024
Devon Energy (United States)
2016-2023
William Harvey Hospital
2023
East Kent Hospitals University NHS Foundation Trust
2023
Northwestern Memorial Hospital
2017-2021
Ascension Providence Hospital
2018-2020
Detroit Medical Center
2020
Northwestern University
2017
Memorial Sloan Kettering Cancer Center
2015
Cornell University
2015
Community-acquired pneumonia is a leading infectious cause of hospitalization and death among U.S. adults. Incidence estimates confirmed radiographically with the use current laboratory diagnostic tests are needed.
The National Lung Screening Trial (NLST) is a randomized multicenter study comparing low-dose helical computed tomography (CT) with chest radiography in the screening of older current and former heavy smokers for early detection lung cancer, which leading cause cancer-related death United States. Five-year survival rates approach 70% surgical resection stage IA disease; however, more than 75% individuals have incurable locally advanced or metastatic disease, latter having 5-year less 5%. It...
Multiple strategies are currently being used to manage patients who present with indeterminate solitary pulmonary nodules (SPN). We have decision-analysis models assess the cost-effectiveness of various for diagnosis and management SPN. Four decision were compared: a wait watch strategy, surgery computed tomography (CT)-based CT-plus-positron emission (PET) strategy. An incremental ratio (ICER) was compare all strategy.A CT-plus-PET strategy most cost-effective over large pretest likelihood...
This study evaluated the efficacy and safety of pemetrexed, carboplatin, bevacizumab followed by maintenance pemetrexed in patients with chemotherapy-naive stage IIIB (effusion) or IV nonsquamous non-small-cell lung cancer (NSCLC).Patients received 500 mg/m(2), carboplatin area under concentration-time curve 6, 15 mg/kg every 3 weeks for six cycles. For response stable disease, were continued until disease progression unacceptable toxicity.Fifty enrolled treatment. The median follow-up was...
Purpose AUY922 is an HSP90 inhibitor that causes degradation of HSP chaperones and their client proteins, including epidermal growth factor receptor. We conducted a phase I/II trial to evaluate erlotinib for patients with EGFR-mutant lung cancer disease progression during treatment. Patients Methods All had developed acquired resistance after treatment underwent repeat tumor biopsies before study entry assess EGFR T790M. In I, 18 were treated intravenously once per week day in 28-day cycles...
The purpose of this research is to characterize solitary pulmonary nodules as benign or malignant based on quantitative measures extracted from high resolution CT (HRCT) images. High images 31 patients with and definitive diagnoses were obtained. these cases (14 17 malignant) determined either radiologic follow‐up pathological specimens. Software tools developed perform the classification task. On HRCT images, identified using semiautomated contouring techniques. From resulting contours,...
Two hundred seventy-five computed tomographic (CT) angiograms of the thoracic aorta were obtained over a period approximately 4 years in patients with suspected or known aortic dissection. In all cases, unenhanced images initially obtained, followed by contrast material-enhanced images. A variety pitfalls encountered that mimicked These attributable to technical factors (eg, improper timing material administration relative image acquisition); streak artifacts generated high-attenuation...
The clinical significance of pneumonia visualized on CT scan in the setting a normal chest radiograph is uncertain.
No spontaneous air leak case series have been described in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patient population thus far. We seven cases we found our disease 2019 (COVID-19) positive 976-patient cohort. Five out of patients eventually required mechanical ventilation, and one these died. All who demonstrated radiological leaks after intubation other precipitating factors offered literature far played a role population. presume that lung injury leading to...
Abstract This paper presents a multidisciplinary approach to evaluating reservoir drainage patterns and hydraulic stimulation interactions among development of both existing new wells. Analysis an extensive diagnostic package focuses on the potential capture stranded reserves via refracs infill drilling within black oil window Lower Eagle Ford Shale, DeWitt County, Texas. The project consists unique setup primary (parent) wells, horizontal well devoted exclusively observation. Liner were...
Objectives The aim of the study was to explore factors surrounding modification first antiretroviral (ARV) regimen where drug switch occurred 3 months or more after initiation. Reference made British HIV Association (BHIVA) guidelines on management. Methods A case note and questionnaire‐based audit carried out. Results Toxicity single most important reason for ARV change only, a contributory, cause in over half patients. Virological failure, adherence issues, requirement treatment...
Pulmonary thromboembolism: spectrum of findings on CT.S M Greaves, E Hart, K Brown, D A Young, P Batra and R AberleAudio Available | Share
8036 Background: AUY922 is a synthetic HSP90 inhibitor that degrades client onco-proteins including EGFR. Preclinical studies demonstrate inhibitors are effective agents against models of AR in EGFR-mutant lung cancer cell lines and xenografts harboring the “gatekeeper” mutation EGFR T790M. Pts with mutations who develop often continue E 2nd-line therapies to avoid “disease flare” associated discontinuing TKI. This phase II study combines for treatment pts RECIST-progression on 1st-line...
We validate a deep learning model predicting comorbidities from frontal chest radiographs (CXRs) in patients with coronavirus disease 2019 (COVID-19) and compare the model's performance hierarchical condition category (HCC) mortality outcomes COVID-19. The was trained tested on 14,121 ambulatory CXRs 2010 to at single institution, modeling select using value-based Medicare Advantage HCC Risk Adjustment Model. Sex, age, codes, risk adjustment factor (RAF) score were used. validated 413...
7601 Background: Pemetrexed in combination with carboplatin has been shown to have promising activity and favorable toxicity profile NSCLC. Bevacizumab improve response rates survival pts advanced non-squamous NSCLC when combined paclitaxel. This study of pemetrexed plus bevacizumab was designed evaluate the estimate regimen this pt population. Methods: Eligibility required that were chemotherapy-naive, had stage IIIB (effusion)/IV NSCLC, PS 0–1, no evidence CNS metastases. Pts received 500...
Abstract With the use of both azimuthal propagation resistivity main and cross component data, anisotropy its dip azimuth angles a massive formation (anisotropic shale or laminated sand) can be determined. The accuracy determined parameters depends on amount available data. A minimum data are two frequency components real quadrature components. boundary effects will distort solution eventually; however, enhanced processing minimize to extend algorithm certain distance away from boundary.
Abstract This case study details the use of Sealed Wellbore Pressure Monitoring (SWPM) to improve characterization fracture geometry and propagation during stimulation inter-connected stacked pay in South Texas Eagle Ford Shale. The SWPM workflow utilizes surface pressure gauges detect hydraulically induced arrivals athorizontal monitor locations adjacent stimulated wellbore (Haustveit et al. 2020). A staggered development Dewitt County provided opportunity jointly evaluateprimary completion...
CT-guided catheter drainage of loculated thoracic air collections in mechanically ventilated patients with acute respiratory distress syndrome.K S Chon, E vanSonnenberg, H B D'Agostino, R M O'Laoide, G Colt and HartAudio Available | Share