Cynthia de Luise

ORCID: 0000-0003-1031-4233
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About
Contact & Profiles
Research Areas
  • Parkinson's Disease Mechanisms and Treatments
  • Emergency and Acute Care Studies
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Cardiac Valve Diseases and Treatments
  • Advanced Breast Cancer Therapies
  • Respiratory viral infections research
  • Data-Driven Disease Surveillance
  • Hip and Femur Fractures
  • Gallbladder and Bile Duct Disorders
  • Breast Cancer Treatment Studies
  • Gastrointestinal disorders and treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pediatric Hepatobiliary Diseases and Treatments
  • Tuberculosis Research and Epidemiology
  • Colorectal Cancer Screening and Detection
  • Lung Cancer Research Studies
  • Neuroendocrine Tumor Research Advances
  • Cardiac Arrhythmias and Treatments
  • Pulmonary Hypertension Research and Treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Congenital Anomalies and Fetal Surgery
  • Cardiovascular Function and Risk Factors
  • Bone health and osteoporosis research
  • Parvovirus B19 Infection Studies
  • Cancer Treatment and Pharmacology

Pfizer (United States)
2007-2025

Clinica Mediterranea
2019

Rutgers, The State University of New Jersey
2007-2008

Cabrini Medical Center
1999

Icahn School of Medicine at Mount Sinai
1999

Background: Assessing the real-world safety of preventive products against respiratory syncytial virus (RSV) in pregnant women holds significant public health implications, especially as vaccination programs become more widespread. This generic protocol describes a post-authorisation study (PASS) to evaluate RSV using target trial emulation framework. Methods: protocol, adapted from an ongoing PASS, is designed framework vaccine women. Emulating conditions have ability minimise confounding...

10.3390/vaccines13030272 article EN cc-by Vaccines 2025-03-05

Abstract Background There is limited real-world safety information on palbociclib for treatment of advanced stage HR+/HER2- breast cancer. Methods We conducted a cohort study cancer patients initiating and fulvestrant from February 2015 to September 2017 using the HealthCore Integrated Research Database (HIRD), longitudinal claims database commercial health plan members in United States. The historical comparator comprised monotherapy January 2011 2015. Propensity score matching Cox...

10.1186/s12885-021-07790-z article EN cc-by BMC Cancer 2021-01-25

Real-world data from large administrative claims databases in Japan have recently become available, but limited evidence exists to support their validity. VALIDATE-J validated claims-based algorithms for selected cancers Japan.VALIDATE-J was a multicenter, cross-sectional, retrospective study. Disease-identifying were used identify diagnosed between January or March 2012 and December 2016 using two hospitals Japan. Positive predictive values (PPVs), specificity, sensitivity calculated...

10.1002/pds.5263 article EN cc-by Pharmacoepidemiology and Drug Safety 2021-05-08

Abstract Purpose Claims databases offer large populations for research, but lack clinical details. We aimed to develop predictive models identify estrogen receptor positive (ER+) and human epidermal growth factor negative (HER2−) early breast cancer (ESBC) advanced stage (ASBC) in a claims database. Methods Female cases Anthem's Cancer Care Quality Program served as the gold standard validation sample. Predictive were developed from knowledge empirically data using logistic lasso regression....

10.1002/pds.4681 article EN Pharmacoepidemiology and Drug Safety 2018-11-09

Abstract Aim Validity of Algorithms in Large Databases: Infectious Diseases, Rheumatoid Arthritis, and Tumor Evaluation Japan (VALIDATE‐J) study examined algorithms for identifying rheumatoid arthritis (RA) Japanese claims data. Methods VALIDATE‐J was a multicenter, cross‐sectional retrospective study. Disease‐identifying were used to detect RA diagnosed between January 2012 December 2016 using data from two hospitals. An diagnosis confirmed one four gold standard definitions. Positive...

10.1111/1756-185x.15001 article EN cc-by-nc-nd International Journal of Rheumatic Diseases 2023-12-31

Abstract Background To validate Japanese claims-based disease-identifying algorithms for herpes zoster (HZ), Mycobacterium tuberculosis (MTB), nontuberculous mycobacteria infections (NTM), and Pneumocystis jirovecii pneumonia (PJP). Methods VALIDATE-J, a multicenter, cross-sectional, retrospective study, reviewed the administrative claims data medical records from two hospitals. Claims-based were developed by experts to identify HZ, MTB, NTM, PJP cases among patients treated 2012–2016....

10.1186/s12879-023-08466-8 article EN cc-by BMC Infectious Diseases 2023-10-03
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