- Diabetes, Cardiovascular Risks, and Lipoproteins
- Obesity, Physical Activity, Diet
- Alzheimer's disease research and treatments
- Body Composition Measurement Techniques
- Lipoproteins and Cardiovascular Health
- Sulfur-Based Synthesis Techniques
- Diabetes Treatment and Management
- Catalytic C–H Functionalization Methods
- Cardiovascular Health and Risk Factors
- Birth, Development, and Health
- Salivary Gland Tumors Diagnosis and Treatment
- Corneal surgery and disorders
- Phytochemicals and Antioxidant Activities
- Cardiovascular Disease and Adiposity
- Biochemical Analysis and Sensing Techniques
- Metabolism, Diabetes, and Cancer
- Phytochemistry and Biological Activities
- Adipokines, Inflammation, and Metabolic Diseases
- Ocular Surface and Contact Lens
- Regulation of Appetite and Obesity
- Corneal Surgery and Treatments
- Cholesterol and Lipid Metabolism
- Nutritional Studies and Diet
- Cancer, Lipids, and Metabolism
- Gout, Hyperuricemia, Uric Acid
Eye & ENT Hospital of Fudan University
2011-2024
Jiangsu University
2024
Jiyang College of Zhejiang A&F University
2017-2024
Zhejiang A & F University
2018-2024
Ningxia Medical University
2020-2022
Ruijin Hospital
2020
Shanghai Jiao Tong University
2020
Southeast University
2013-2019
Zhongda Hospital Southeast University
2013-2019
Fudan University
2009-2019
Abstract Although Type 2 diabetes mellitus (T2DM) is a well-recognized risk factor for dementia, the neural mechanisms that underlie cognitive impairment in T2DM remain unclear. This study uses resting-state functional magnetic resonance imaging (fMRI) to examine attention network alterations and their relationships impaired performance. Data-driven independent component analysis was applied fMRI data from 38 patients 32 healthy controls identify dorsal (DAN) ventral (VAN). Correlations were...
Objective Receptor for advanced glycation end products (AGEs; RAGE) binds to both AGEs and amyloid-beta peptides. RAGE is involved in chronic complications of type 2 diabetes Alzheimer's disease. We aimed investigate the roles RAGE, Gly82Ser polymorphism mild cognitive impairment (MCI) among patients. Methods Of 167 hospitalized patients recruited, 82 satisfied diagnostic criteria MCI, 85 matched control individuals were classified as non-MCI. Demographic data collected, soluble (sRAGE)...
We explored the response of photosynthetic capacity to nitrogen (N) deposition among Larix gmelinii trees in different crown classes (e.g. suppressed, intermediate, and dominant trees) a 12-year field experiment forest Greater Khingan Mountains Northeast China. Four N-addition treatments were established: control (CK), low N (LN), medium (MN), high (HN) (0, 25, 50, 75 kg N·ha−1·year−1, respectively). Photosynthesis its influencing factors measured 2023. Nitrogen addition significantly...
To quantitatively investigate the pathological subtypes of lacrimal gland adenoid cystic carcinoma (LGACCs), tumor immune microenvironment in each subtype, and relation to survival. In this retrospective study, subtype was determined by H&E staining. Multiplex immunochemistry performed define specific cells. The (TIME) sketched sequential image scanning reconstructed a cytometry platform. Eighteen patients with adequate paraffin blocks diagnosed LGACC from 2012 2021 were included study....
Type 2 diabetes mellitus (T2DM) and hypertension are both associated with cognitive impairment brain function abnormalities. We investigated whether abnormal cerebral blood flow (CBF) patterns exists in T2DM patients possible relationships between aberrant CBF performance. Furthermore, we examined the influence of on alterations patients. (n = 38) non-T2DM subjects 40) were recruited from clinics, hospitals, normal community health screenings. Cerebral images collected analyzed using...
Genetic diversity analysis and DNA finger printing are very useful in breeding programs, seed conservation management. Jute (Corchorus spp.) is the second most important natural fiber crop after cotton. fingerprinting studies jute using SSR markers limited. In this study, 58 accessions, including two control varieties (Huangma 179 Kuanyechangguo) from official variety registry China were evaluated with 28 pairs of primers. A total 184 polymorphic loci identified. Each primer detected 3 to 15...
Objective: Type 2 diabetes mellitus (T2DM) is related to an elevated risk of mild cognitive impairment (MCI). Plasma clusterin reported associated with the early pathology Alzheimer's disease (AD) and longitudinal brain atrophy in subjects MCI. The rs11136000 single nucleotide polymorphism within (CLU) gene also AD. We aimed investigate associations among plasma clusterin, genotype T2DM-associated Methods: A total 231 T2DM patients, including 126 MCI 105 cognitively healthy controls were...
Background: Metabolic disturbances, such as hyperglycemia, hyperlipidemia, and obesity, are thought to be risk factors for Alzheimer's disease. Objective: This study aimed investigate whether adipokine leptin soluble receptor (sOBR) levels correlated with mild cognitive impairment (MCI) metabolic status of the patients type 2 diabetes mellitus (T2DM). Methods: Total 169 T2DM were recruited divided according Montreal Cognitive Assessment (MoCA) score. Their cognition parameters extensively...
We aim to investigate whether decreased interhemispheric functional connectivity exists in patients with type 2 diabetes mellitus (T2DM) by using resting-state magnetic resonance imaging (rs-fMRI). In addition, we sought determine deficits associated cognition and insulin resistance (IR) among T2DM patients. compared the resting state of 32 30 healthy controls rs-fMRI. Partial correlation coefficients were used detect relationship between rs-fMRI information cognitive or clinical data....
Abstract The relationship between visceral adiposity index (VAI) and unhealthy metabolic phenotype remained unclear in children adolescents. This study aimed to investigate their association compared the ability of VAI traditional indicators (body mass index, waist circumference waist-to-height ratio) predict metabolically among normal-weight, overweight obese In this cross-sectional study, 1722 adolescents aged 12–18 years were selected by cluster random sampling, underwent a questionnaire...
Background:Plasminogen activator inhibitor 1 (PAI-1) and tissue plasminogen (tPA) are involved in the complications of type 2 diabetes mellitus (T2DM) early pathology Alzheimer’s disease. Objective:This study aimed to investigate association between plasma PAI-1, tPA/PAI-1 mola r ratio, mild cognitive impairment (MCI) Chinese T2DM patients. Methods:A total 162 patients were recruited divided into two groups according Montreal Cognitive Assessment score. Demographic data collected, PAI-1 tPA...
Pharmacognosy Magazine ,2019,15,60,124-129.DOI:10.4103/pm.pm_162_18Published:January 2019Type:Original Article Authors:Luo Yang, Cai Rong-Rong, Fang Ji-Li, and Yuan Ke Author(s) affiliations:Luo Yang1, Rong-Rong2, Ji-Li1, Ke3 1College of Forest Biotechnology, Zhejiang Agriculture Forestry University, Lin'an, China 2 iyang College Zhu'ji, 3College Lin'an; Jiyang Abstract:Background: Anthocyanin, a subcategory flavonoid, is natural water-soluble pigment. There are many plants rich in...
Abstract Type 2 diabetes mellitus (T2DM) is a low-grade chronic inflammatory diseases, which have been implicated in the pathogenesis of cognitive decline. We aim to evaluate associations between markers and risk mild impairment (MCI) T2DM. This study 140 diabetic patients involved 71 with MCI 69 controls. Clinical parameters, neuropsychological tests, high sensitivity C reactive protein (hsCRP), interleukin-6 (IL-6), lipoprotein-associated Phospholipase A2 (Lp-PLA2) mass activity were...
Fungal interface keratitis by Candida species can occur several weeks to months after deep anterior lamellar keratoplasty (DALK). Here, we report a case of early-onset fungal glabrata DALK.A 31-year-old Chinese man complained decreased vision 4 days an uneventful DALK for keratoconus. White cream-colored deposits were identified under slit-lamp examination. The confocal scan disclosed clusters hyperreflective granular 2 μm at the interface, without evidence inflammation or hyphae-like...
Purpose To report the clinical and histopathologic characteristics prognoses of three ocular juvenile xanthogranuloma (JXG) cases. Case Reports Three cases were included in this study. The first case involved a 5-year-old girl with an enlarging yellowish mass at limbus corneal involvement. Ultrasound biomicroscopy showed poorly demarcated involving underlying cornea sclera. was excised combination lamellar keratoplasty procedure. No recurrence seen 2-year follow-up. second 2-year-old boy on...