- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- Phytochemistry and Biological Activities
- Ethnobotanical and Medicinal Plants Studies
- Psidium guajava Extracts and Applications
- Insect Pest Control Strategies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Bee Products Chemical Analysis
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Antibiotics Pharmacokinetics and Efficacy
- Pain Mechanisms and Treatments
- Piperaceae Chemical and Biological Studies
- Antibiotic Resistance in Bacteria
- Pharmacological Effects of Natural Compounds
- Complementary and Alternative Medicine Studies
- Traditional and Medicinal Uses of Annonaceae
- Antimicrobial Resistance in Staphylococcus
- Phytochemistry and Bioactivity Studies
- Research on Leishmaniasis Studies
- Medicinal Plants and Neuroprotection
- Trypanosoma species research and implications
- Medicinal Plant Extracts Effects
- Bioactive Natural Diterpenoids Research
- Antifungal resistance and susceptibility
Universidade Regional do Cariri
2016-2025
Universidade Federal do Cariri
2016-2024
Fundação Oswaldo Cruz
2023
Universidade Estadual do Ceará
2021
Universidade de São Paulo
2008-2017
John Wiley & Sons (United Kingdom)
2017
Universidade Federal de Sergipe
2017
Centro Universitário do Norte
2015
Biolog (United States)
2015
Rede de Química e Tecnologia
2014
The applications of nanoparticles in various practical fields, owing to their unique properties compared with bulk materials, have been occupying the minds scientists for several decades. In this regard, a combination pharmacology and nanotechnology has contributed producing newer effective anticancer antimicrobial agents inactivate resistant cancer cells microorganisms, specifically multidrug-resistant ones. physicochemical based on metalloid, metal, metal oxides such as selenium, silver,...
Lippia sidoides Cham. (Verbenaceae) is used in the folk medicine as topical antiseptic skin and mucous membranes its therapeutic effect attributed to thymol presence. The objective of this work was verify chemical composition antibiotic modifying activity essential oil extracted from leaves L. major component thymol. obtained by hydrodistillation analyzed GC/MS. synergistic evaluated using gaseous contact method. (yield 1.06%) GC/MS analysis identified main constituents: (84.9%) p-cymene...
Ethnobotanical studies have contributed significantly in research of plants with therapeutic potential. The aim the present study was to learn about use native medicinal cited by traditional population "cerradão" (savanna woodland) areas Northeast Brazil, providing data on indications species used and their versatility.Semi-structured interviews were conducted basis a standardized questionnaire designed for key informants selected using "snowball" technique. selection potential performed...
Phytol is a diterpene constituent of chlorophyll and has been shown to have several pharmacological properties, particularly in relation the management painful inflammatory diseases. Arthritis one most common these diseases, mainly affecting synovial membrane, cartilage, bone joints. Proinflammatory cytokines, such as TNF-α IL-6, NFκB signaling pathway play pivotal role arthritis. However, mechanisms action phytol its ability reduce levels cytokines are poorly understood, we decided...
Quercetin (QUA), a flavonoid compound, is ubiquitously found in plants and has demonstrated diverse range of biological activities. The primary objective the current study to assess potential antiemetic properties QUA using an vivo silico approach. In this experiment, 4-day-old chicks were purchased induce emesis by orally administering copper sulfate pentahydrate (CuSO4·5H2O) at dose 50 mg/kg (orally). Domperidone (DOM) (6 mg/kg), Hyoscine (HYS) (21 Ondansetron (OND) (5 mg/kg) treated as...
O presente trabalho visou o levantamento etnobotânico das plantas medicinais, verificando a versatilidade espécies utilizadas e consenso de uso e/ou conhecimento entre os informantes, do Distrito Aratama, no Município Assaré, Ceará. As informações etnobotânicas foram obtidas através entrevistas estruturadas semi-estruturadas com moradores locais. Foram citadas 116 fins medicinais pertencentes 103 gêneros 58 famílias destaque para Fabaceae (10ssp.), Asteraceae (7spp.) Lamiaceae (6spp.). Entre...
The aim of this study was to evaluate the chemical profile and antioxidant, antimicrobial antiparasitic activities hydroalcoholic extract leaves Ziziphus joazeiro Mart. (HELZJ). antioxidant DPPH FRAP assays were determined by colorimetric methods HPLC/DAD. antiparasitic, antibiotic antibiotic-modifying activity evaluated microdilution assays. HPLC-DAD assay showed presence mostly tannins flavonoids, such as caffeic acid quercetin. levels polyphenols flavonoids 183.136 mg/g 7.37 extract,...
Silymarin is a standardized extract from the dried seeds of milk thistle ( Silybum marianum L. Gaertn.) clinically used as an antihepatotoxic agent. The aim this study was to investigate antibacterial and antifungal activity silymarin its major constituent (silibinin) against different microbial strains their modulatory effect on drugs utilized in clinical practice. demonstrated antimicrobial little significance bacterial tested, with MIC (minimum inhibitory concentration) values 512 µ g/mL....
Psidium guajava is a Myrtaceae plant whose medicinal properties are recognized in several locations. The use of teas and tinctures prepared from their leaves has been used to combat infections caused by fungi the genus Candida. In this study, aqueous extracts hydroethanolic were tested verify antifungal potential its chemical composition investigated. microbiological assays performed broth microdilution determine minimum inhibitory concentration (MIC) these fungicidal was (MFC) subculturing...