- Intracerebral and Subarachnoid Hemorrhage Research
- Radiomics and Machine Learning in Medical Imaging
- COVID-19 diagnosis using AI
- Hepatocellular Carcinoma Treatment and Prognosis
- Plant Gene Expression Analysis
- Blood properties and coagulation
- Neurofibromatosis and Schwannoma Cases
- AI and Big Data Applications
- Acute Ischemic Stroke Management
- Colorectal Cancer Screening and Detection
- MRI in cancer diagnosis
- Advanced Technologies in Various Fields
- Phonocardiography and Auscultation Techniques
- Medical Imaging and Analysis
- AI in cancer detection
- Photosynthetic Processes and Mechanisms
- Amyotrophic Lateral Sclerosis Research
- Artificial Intelligence in Healthcare
- COVID-19 Clinical Research Studies
- Neuroendocrine Tumor Research Advances
- Signaling Pathways in Disease
- Ion channel regulation and function
- Spinal Cord Injury Research
- Gastrointestinal Tumor Research and Treatment
- Erythrocyte Function and Pathophysiology
Fujian Agriculture and Forestry University
2025
Tsinghua University
2021-2024
Shanghai Jiao Tong University
2024
Shanghai Sixth People's Hospital
2024
PLA Academy of Military Science
2023
Chinese PLA General Hospital
2023
Army Medical University
2019-2022
Southwest Hospital
2019-2022
National Engineering Research Center for Information Technology in Agriculture
2022
First Affiliated Hospital of Jinan University
2021
The BRI1-EMS-SUPPRESSOR 1 (BES1) family comprises plant-specific transcription factors, which are distinguished by atypical bHLH domains. Over the past two decades, genetic and biochemical studies have established that members of crucial for regulating expression genes involved in brassinosteroid (BR) response rapeseed. Due to significance BES1 gene family, extensive research has been conducted investigate its functional properties. This study presents a comprehensive identification...
BACKGROUND:The Piezo1 protein ion channel is a novel mechanical activated which related to signal transduction. However, the function of mechanically had not been explored. In this study, we explored in human osteosarcoma (OS) cells apoptosis, invasion, and cell proliferation. MATERIAL AND METHODS:Reverse transcription polymerase chain reaction (RT-PCR) western-blotting were used detect expression protein. CCK-8, Transwell experiments AV-PI detected proliferation, invasion apoptosis....
Intracerebral haemorrhage (ICH) is a devastating disease that characterized by high morbidity and mortality. ICH has an annual incidence of 10–30/100 000 people accounts for approximately 10% to 30% all types stroke. mostly occurs at the basal ganglia, which rich in nerve fibres; thus, hemiplegia quite common patients with partial sensory disturbance ectopic blindness. In clinic, those symptoms are considered originate from white matter injury area, but exact mechanisms unknown, currently,...
Abstract Motor function deficit induced by white matter injury (WMI) is one of the most severe complications intracerebral haemorrhage (ICH). The degree WMI closely related to prognosis patients after ICH. However, current behavioural assessment motor used in ICH mouse model mainly based on that for ischaemic stroke and lacks methods accurately respond WMI. Here, a series easy-to-implement tests were performed detect deficits mice results showed grip strength test modified pole not only can...
Rationale: Coronavirus disease 2019 (COVID-19) has caused a global pandemic.A classifier combining chest X-ray (CXR) with clinical features may serve as rapid screening approach.Methods: The study included 512 patients COVID-19 and 106 influenza A/B pneumonia.A deep neural network (DNN) was applied, derived from CXR findings formed fused for diagnosis prediction. Results:The of showed different patterns.Patients experienced less fever, more diarrhea, salient hypercoagulability.Classifiers...
The mitochondrial permeability transition pore is a nonspecific transmembrane channel. Inhibition of opening has been shown to alleviate swelling, calcium overload, and axonal degeneration. Cyclophilin D an important component the pore. Whether cyclophilin participates in impairment injury after intracerebral hemorrhage not clear. In this study, we established mouse models vivo by injection autologous blood oxyhemoglobin into striatum Thy1-YFP mice, which pyramidal neurons axons express...
The objective is to explore the role of astrocytic transient receptor potential ankyrin 1 (TRPA1) in glial phenotype transformation neuroinflammation after intracerebral hemorrhage (ICH). Wild-type astrocytes and TRPA1 −/− were subjected 6-h hemin treatment, calcium ions transcriptome sequencing assessed. A mouse autologous blood injection ICH model was established evaluate proliferation phenotypes microglia around hematoma. behavioral performance wild-type mice Knockout decreased treatment...
Accurate preoperative evaluation of microvascular invasion (MVI) in hepatocellular carcinoma (HCC) is crucial for surgeons to make informed decisions regarding appropriate treatment strategies. However, it continues pose a significant challenge radiologists. The integration computer-aided diagnosis utilizing deep learning technology emerges as promising approach enhance the prediction accuracy.
Abstract Background: A accurate preoperative evaluation of microvascular invasion (MVI) in hepatocellular carcinoma can help surgeons choose the appropriate treatment, while it still remains challenge for radiologists. Computer-aided diagnosis with deep learning technology may be one solutions to improve prediction accuracy. Methods: MRI six different sequences were included this experiment. neural network was used segment after a cross-sequence registration preprocess. Radiomics features...
Imbalanced and even long-tail distribution of different categories is a challenge for multi-class classification problem, especially medical image diagnose whose data usually imbalanced. Toward this issue, we proposed an end-to-end multi-agent network called Tria-geNet, which combined multiple selectors diagnostic agents. All are guided to agents by selectors, every agent expert in specific group categories. This process, similar triage hospitals, helps decrease the unbalance between both...
Objective. This paper uses the nearest neighbor propagation clustering segmentation algorithm to explore impact of PET/CT image technology on lung cancer radiotherapy planning. Methods. In this paper, scan was performed 12 patients with nonmetastatic cancer. The self-written automatic program based PCNN model is used segment PET target area, and then tumor area manually sketched CT images images, intensity-modulated plan formulated same parameters. Target volume dose distribution were...