A5100331107- Urban Transport and Accessibility
- China's Socioeconomic Reforms and Governance
- Cell death mechanisms and regulation
- Cell Image Analysis Techniques
- RNA regulation and disease
- Mitochondrial Function and Pathology
- Sports, Gender, and Society
- Sport and Mega-Event Impacts
- interferon and immune responses
- Urban and Rural Development Challenges
- Environmental Quality and Pollution
- Transportation Planning and Optimization
- Urban Green Space and Health
- Human Mobility and Location-Based Analysis
- stochastic dynamics and bifurcation
- China's Ethnic Minorities and Relations
- Atmospheric chemistry and aerosols
- Local Government Finance and Decentralization
- Electrochemical Analysis and Applications
- Air Quality Monitoring and Forecasting
- Traffic and Road Safety
- Adventure Sports and Sensation Seeking
- RNA Interference and Gene Delivery
- ATP Synthase and ATPases Research
- Urban Planning and Governance
Xiamen University
2014-2025
Jilin University
2023
Beijing University of Chemical Technology
2022
PLA Information Engineering University
2022
Hong Kong Polytechnic University
2022
Yancheng Teachers University
2021
The University of Melbourne
2018
Institute of Theoretical Physics
2014
Southwest University
2014
Collaborative Innovation Center of Chemistry for Energy Materials
2014
There remains a significant gap in our quantitative understanding of crosstalk between apoptosis and necroptosis pathways. By employing the SWATH-MS technique, we quantified absolute amounts up to thousands proteins dynamic assembling/de-assembling TNF signaling complexes. Combining SWATH-MS-based network modeling experimental validation, found that when RIP1 level is below ~1000 molecules/cell (mpc), cell solely undergoes TRADD-dependent apoptosis. When above mpc, pro-caspase-8 RIP3 are...
Biphasic amplitude dynamics (BAD) of oscillation have been observed in many biological systems. However, the specific topology structure and regulatory mechanisms underlying these biphasic remain elusive. Here, we searched all possible two-node circuit topologies identified core oscillator that enables robust oscillation. This consists a negative feedback loop between two nodes self-positive input node, which result fast slow nodes, thereby achieving relaxation Landscape theory was employed...
With regard to the aims of achieving “Dual Carbon” goal and addressing significant greenhouse gas emissions caused by urban expansion, there has been a growing emphasis on spatial research prediction carbon emissions. This article examines land use data from 2000 2020 combines Grid PLUS model predict in 2030 through multi-scenario simulation. The findings indicate following: (1) Between 2020, construction increased 95.83%, with also increasing. (2) By 2030, for NDS (natural development...
Fan Yusui, who had experienced the Chinese battlefields of World War II and Civil War, always fought for unity nation. He joined Kuomintang in early stage his political career, after experiencing wartime society, he saw true nature Kuomintang. Finally, broke with Chiang Kai-shek 1949 Communist Party China. This article explores reasons behind Yusui’s struggle to unite people shift from
Recent policy initiatives for urban development have changed the relationships among stakeholders in China’s consolidation processes. Building upon Giddens’ (Giddens A (1984) The Constitution of Society: Outline Theory Structuration. Berkeley, CA: University California Press.) structuration theory and Ostrom’s (Ostrom E (2005) Understanding Institutional Diversity. Princeton, NJ: Princeton Press) institutional analysis thesis, this paper develops a power arena analytic framework, uses it to...
BACKGROUND: The therapeutic effect and mechanism of robot-assisted upper limb training (RT) combined with intermittent theta burst stimulation (iTBS) for stroke patients are unclear. OBJECTIVE: purpose this study was to evaluate changes in brain activation after combination therapy RT alone using functional near-infrared spectroscopy (fNIRS). METHODS: Patients were randomly assigned two groups (iTBS + Group, n = 18, 18). Training conducted five times a week four weeks. fNIRS used measure...
Real-time evaluations of the severity depressive symptoms are great significance for diagnosis and treatment patients with major disorder (MDD). In clinical practice, evaluation approaches mainly based on psychological scales doctor-patient interviews, which time-consuming labor-intensive. Also, accuracy results depends subjective judgment clinician. With development artificial intelligence (AI) technology, more machine learning methods used to diagnose depression by appearance...
As a special type of resources, salt lakes have important scientific, economic values and environmental effects. Salt are store houses mineral salts. The productive elements (such as lithium, magnesium, potassium, boron, etc.) among lakes, precious resources with strategic interest for the development economics society China. This paper briefly reviews characteristics techniques in comprehensive utilization Qinghai lake proposes some suggestions well political level.
Positive youth development (PYD) is an innovative approach to protect students from mental health problems and promote their positive holistic development. Although there are many studies on the beneficial effects of PYD programs in high school community contexts, it not clear whether subjects adopting principles can for university students. Moreover, unclear such effective under COVID-19, where commonly taught via "hybrid" mode (i.e., face-to-face plus online teaching). The present study...
The walkability of a neighborhood is important for alleviating transport problems and improving the social physical wellbeing residents. However, it unclear to what extent high contributes positive attitudes about walking experiences on university campuses. In addition, little known mechanism by which attitude influences affective students. Therefore, this study aimed analyze relationship between campus students’ experience, as well explain role mediator relationship. To address these...
Abstract One of the basic questions in aging field is whether there a fundamental difference between lower invertebrates and mammals. A major mammals abundancy noncoding RNAs, most which are not conserved. We have previously identified RNA Terc-53 that derived from component telomerase Terc. To study its physiological functions, we generated two transgenic mouse models overexpressing wild-type early-aging Terc−/− backgrounds. mice showed age-related cognition decline shortened life span,...
Abstract Uveal melanoma (UM) patients face a significant risk of distant metastasis, closely tied to poor prognosis. Despite this, there is dearth research utilizing big data predict UM metastasis. This study leveraged machine learning methods on the Surveillance, Epidemiology, and End Results (SEER) database forecast probability Therefore, information from SEER (2000–2020) was split into 7:3 ratio training set an internal test based metastasis presence. Univariate multivariate logistic...
The mechanism of isoprenaline exerting its effects on cardiac pacemaking and driving in sick sinus syndrome is controversial unresolved. In this paper, mathematical models for rabbit sinoatrial node cells were modified by incorporating equations the known dose-dependent actions various ionic channel currents, intracellular Ca 2+ transient, and<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Continuous reform efforts in urban China have scaled back direct government intervention by introducing freer land market trials. Anecdotal evidence reveals, however, that the liberal approach has yielded little advantageous result Shenzhen, where such experiments are pioneered. By building on new institutionalist concepts and analyzing primary secondary data, this paper demonstrates deficiencies of formal rules created a policy vacuum, while informal constraints increased project...
Mitochondrial permeability transition pore (PTP), a key regulator of cell life and death processes, is triggered by calcium ions (Ca2+) potentiated reactive oxygen species (ROS). Although the two modes PTP opening, i.e., transient persistent, have been identified for long time, its dynamical mechanism still not fully understood. To test proposed hypothesis that opening acts as tristable switch, which characterized low, medium, high open probability, we develop three-variable model focused on...
Emerging evidences have suggested that oscillation is important for the induction of cell death. However, whether and how behavior involved required necroptosis remain elusive. To address this question, a minimal necroptotic circuit proposed based on CNS pathway. Stochastic parameter analysis demonstrates essential structure constituted by paradoxical component embedded with positive feedback among three protein nodes, i.e., RIP1, caspase-8, RIP3. Distribution characteristics all parameters...
The Chinese regime in urban redevelopment has evolved from a command type to one that seems committed adopting the successful elements of participatory institutions. Recent studies mostly focus on analysis cities populated by Han ethnic group and, as such, are susceptible ethnographical and cultural bias. Building upon concepts habitus nomocratic-teleocratic imbrication, this article investigates variegated forms governance projects through comparative view critical geopolitics with stark...
Abstract Previously reported fused‐pentagon fullerenes stabilized by exohedral derivatization do not share the same cage with those endohedral encapsulation. Herein we report crystallographic identification of #4348 C 66 Cl 10 , which has as that previously Sc 2 @C . According to geometrical data both strain relief (at fused pentagons) and local aromaticity (on remaining sp ‐hybrided carbon framework) contribute stabilization this long‐sought atom cage.