A5041400311- Tracheal and airway disorders
- Cardiac Ischemia and Reperfusion
- Ear Surgery and Otitis Media
- Airway Management and Intubation Techniques
- Anesthesia and Neurotoxicity Research
- Dysphagia Assessment and Management
- Cardiac tumors and thrombi
- Immunodeficiency and Autoimmune Disorders
- Pneumonia and Respiratory Infections
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Reconstructive Facial Surgery Techniques
- Acute Myocardial Infarction Research
- Voice and Speech Disorders
- Respiratory and Cough-Related Research
- Cardiovascular Effects of Exercise
- Streptococcal Infections and Treatments
- RNA regulation and disease
- Infective Endocarditis Diagnosis and Management
- Nutrition and Health Studies
- Cardiac and Coronary Surgery Techniques
- Blood Coagulation and Thrombosis Mechanisms
- Otolaryngology and Infectious Diseases
- Obstructive Sleep Apnea Research
- Blood disorders and treatments
- Smoking Behavior and Cessation
Cambridge University Hospitals NHS Foundation Trust
2023-2025
National Health and Medical Research Council
2021
Lake Erie College
2019
University College London
2013-2018
University of Pittsburgh
1995-2015
Cardiovascular Institute of the South
2013
Göteborgs Stads
2005
Plano Cancer Institute
2005
Children's Hospital of Pittsburgh
1995-2003
A retrospective study was performed In 117 children with head and neck space infections treated at the Children's Hospital of Pittsburgh from January 1986 through June 1992. Peritonsillar were most common (49%), followed by retropharyngeal (22%), submandibular (14%), buccal (11%), parapharyngeal (2%), canine (2%) infections. The pathogens isolated (N = 78) aerobes β-hemolytic streptococcus (18%) Staphylococcus aureus (18%), anaerobes Bacteroides melaninogenicus (17%) Veillonella...
Abstract Background Acquired angioedema due to C1-inhibitor deficiency (AAE-C1-INH) is very rare compared its prototype, hereditary angioedema. An updated characterisation of the AAE-C1-INH cohort in UK required inform management. Objectives To describe disease burden AAE-C1-INH, long-term prophylaxis (LTP) and clinical, immunochemical treatment profiles AAE-associated diseases UK. Method Retrospective data on 117 patients were collected using a national survey proforma across 25/34 Adult...
Tracheostomy for management of neonatal airway obstruction may be life saving but is associated with complications and developmental problems. As an alternative, the effectiveness internal mandibular distraction osteogenesis was investigated in select patients micrognathia upper obstruction. Preoperative tests (sleep study, direct laryngobronchoscopy, "milk scan" GI reflux) were used to appropriate candidates procedure. Excluded 1) central apnea, 2) severe reflux, 3) other lesions, 4) mild...
Chronic cough is a common complaint among pediatric patients, but little information exists on the types of diagnoses in these patients and therapeutic outcomes.To characterize with chronic presenting to otolaryngology clinics, identify causes treatments, evaluate outcomes.In this retrospective analysis, all medical records for seen at 2 clinics single tertiary care academic center from January 2009 through June 2013 were searched relevant diagnostic codes. Patients younger than 18 years...
Objective. Management of chronic aspiration saliva is a challenge to clinicians. The purpose this report review the clinical course 3 patients with tracheotomy who we have followed for at least 1 year and received constant positive airway pressure (CPAP) as primary treatment ongoing saliva. Methods. Retrospective chart review. Results. We present here congestion persistent hypoxemia in whom diagnosis was established by use radionuclide salivagram. Each these children had obstruction. In an...
This is a Video in Clinical Medicine from the New England Journal of Medicine. Tympanocentesis Children with Acute Otitis Media Overview defined as needle aspiration fluid middle ear. In children acute otitis media, drainage pus ear results rapid and marked improvement symptoms enables clinician to prescribe tailored antimicrobial therapy. video will demonstrate technique tympanocentesis. Indications recommended refractory immunocompromised suppurative complications .
Pseudomonas aeruginosa is a rare cause of suppurative arthritis, accounting for 0 to 5% reported joint infections.1-8 A 23-month-old girl with P. isolated from middle ear fluid developed infection the shoulder same organism. Although otitis media occasionally occurs together infections, associated arthritis has not been previously reported. Case report. CD past medical history significant bilateral myringotomy and tube placement at 1 year age recurrent acute media. She had well subsequently...
Background Left ventricular (LV) thrombus formation remains a wellrecognized complication following acute ST-segment elevation myocardial infarction (STEMI) in the primary percutaneous coronary intervention (PPCI) era, with potential devastating consequences such as embolic stroke. Echocardiography-based assessment of anterior STEMI patients, within first 3 months presentation, has reported an incidence LV thrombi ranging from 8 to 15%. CMR not only provides higher resolution anatomical...
<h3>Background</h3> Ischaemic preconditioning is one of the most potent experimental modalities known to decrease infarct size following ischaemia-reperfusion (IR) injury. Much interest has been stimulated by phenomenon Remote Preconditioning (RIPC) which occurs when a stimulus applied limb remote from heart stimulate cardioprotection. The protection believed be mediated an unidentified humoral factor between 3.5 and 30 kDa. Stromal cell-derived factor-1α (SDF-1α or CXCL12) chemokine 10 kDa...
Ischaemic conditioning is the phenomenon of protection against reperfusion injury via application brief, repeated episodes non-lethal ischaemia.This review has three aims: 1) to briefly explain various categories ischaemic conditioning; 2) explore past clinical trials and their failures; 3) future in realm conditioning.
Pinna deformities, combined with congenital aural atresia, have been a matter of serious debate in the literature as they are associated major aesthetic and functional problems that difficult to manage. These described early 2000 BC. The aim present article is approach whole problem one (pinna malformation atresia) history well current approaches reconstruction.Extensive search medical books were used scientific sources.For many centuries, prevalent view was any surgical attempts reconstruct...