A5101509492- Child Nutrition and Water Access
- Iron Metabolism and Disorders
- Obesity, Physical Activity, Diet
- Folate and B Vitamins Research
- Nutrition, Genetics, and Disease
- Birth, Development, and Health
- Nutritional Studies and Diet
- Advanced Biosensing Techniques and Applications
- Plant biochemistry and biosynthesis
- Immunotherapy and Immune Responses
- Nutrition, Health and Food Behavior
- Hemoglobinopathies and Related Disorders
- Traffic Prediction and Management Techniques
- Immune Response and Inflammation
- SARS-CoV-2 and COVID-19 Research
- Cardiovascular Health and Risk Factors
- Mobile Health and mHealth Applications
- Food Security and Health in Diverse Populations
- Advanced biosensing and bioanalysis techniques
- Natural product bioactivities and synthesis
- Public Health and Nutrition
- Medical and Biological Ozone Research
- Gestational Diabetes Research and Management
- Phytase and its Applications
- Educational Robotics and Engineering
Chinese Academy of Medical Sciences & Peking Union Medical College
2009-2024
Chinese Center For Disease Control and Prevention
2009-2024
National Health and Family Planning Commission
2020-2023
Center for Disease Control
2023
Peking University
2020
Institute of Medical Biology
2014
Northeast Forestry University
2014
China Medical University
2012-2013
Liaoning University of International Business and Economics
2010-2011
Capital Medical University
1991
Obesity increases the risk of many diseases. However, there has been little literature about epidemiology obesity classified by body mass index (BMI) or waist (abdominal obesity) among urban Chinese adults. This study is to fill gap assessing prevalence and associated factors A representative sample 25,196 adults aged 18 74 years in Northeast China was selected measurements height, weight circumference (WC) were taken from 2009–2010. Definitions overweight World Health Organization (WHO)...
The emergence of a series SARS-CoV-2 variants has necessitated the search for broad-spectrum antiviral targets. aryl hydrocarbon receptor (AhR) senses tryptophan metabolites and is an immune regulator. However, role AhR in infection whether can be used as target therapy against its are yet unclear. Here, we show that with activates signaling facilitates viral replication by interfering IFN-I-driven immunity up-regulating ACE2 expression. pharmacological blockade or knockout reduces variants'...
Background: Concentrations of ambient air pollution and pollutants in China have changed considerably during the last decade. However, few studies evaluated effects current on health kindergarten children.Methods: We studied 6730 Chinese children (age, 3–7 years) from 50 kindergartens 7 cities Northeast 2009. Parents or guardians completed questionnaires that asked about children’s histories respiratory symptoms risk factors. Three-year concentrations particles with an aerodynamic diameter...
Abstract In China, a full fat soy powder mixed with multiple micronutrient powders ( Ying Yang Bao (YYB)) was developed, and the efficacy of YYB shown in controlling anaemia improving child growth development. However, prior to 2008, there no sustainable way provide vulnerable populations, except through free distribution by government. This study test concept public‐private partnership (PPP) deliver evaluate effectiveness marketing PPP. Programme activities included development...
Radix bupleuri, roots of Bupleurum species, is a widely used traditional Chinese medicine. Here, we compared the root transcriptomes both chinense DC. and scorzonerifolium Willd. A total 313 483 342 263 high quality expressed sequence tags were obtained, respectively. In addition, 17 117 (59.2%) 19 416 (62.8%) unigenes for B. had homologous genes in opposite dataset. For chinense, Kyoto Encyclopedia Genes Genomes database (KEGG) annotation identified carbohydrate metabolism, energy...
Abstract Objectives To assess trends and differences in child malnutrition by population subgroups among infants aged 6-23 months China’s poorest rural counties. Design Six consecutive cross sectional surveys were conducted annually. Setting The study was 116 counties 19 provinces from 2016 to 2021, representing 832 Participants A total of 210 088 participants selected through a multistage cluster sampling procedure; all months. Main outcome measures Prevalence anaemia, stunting, wasting,...
The therapeutic effects of NaFeEDTA-fortified soy sauce on anaemic students were investigated. Three hundred and four iron-deficient school children (11-17 years) randomly assigned to three treatment groups: control group (consuming non-fortified sauce), low-NaFeEDTA fortified sauce, providing 5 mg Fe/day) high-NaFeEDTA 20 Fe/day). Blood haemoglobin (Hb) levels determined before after 1 month, 2 months 3 intervention. In addition, serum iron (SI), ferritin (SF), free erythrocytic porphyrin...
In higher eukaryotes, introns are usually required for efficient pre-mRNA processing. However, some viruses have alternative approaches involving posttranscriptional regulatory elements (PREs) to enhance intronless heterologous gene expression through enabling stability and 3′ end formation, facilitate the nucleocytoplasmic export of unspliced mRNAs. current study, we compared human cytomegalovirus (hCMV) immediate/early (IE) intronA, as well virus-derived PREs—the PRE Hepatitis B virus...
This study aimed to evaluate the prevalence of malnutrition and investigate associated factors stunting among 6–23-month-old infants in poor rural areas central China. The China Nutrition Improvement Project on Children Poor Areas was conducted 56 national-level counties seven provinces 2019. We performed a multivariate binary logistic regression analysis determine stunting. cross-sectional included 17,193 infants. overall highest (3.9%), followed by overweight (3.0%), underweight (2.1%),...
The present pilot project aimed to assess the effectiveness of social mobilization and marketing in improving knowledge, attitudes practices (KAP) Fe status an Fe-deficient population.In uncontrolled, before-after, community-based study, strategies were applied. main outcomes included KAP Hb level measured at baseline, 1 year later 2 years later.One urban county two rural counties Shijiazhuang Municipality, Hebei Province, China.Adult women older than 20 age young children aged from 3 7...
The traditional vaccine adjuvant research is mainly based on the trial and error method, mechanisms underlying immune system stimulation remaining largely unknown. We previously demonstrated that heparan sulfate (HS), a TLR-4 ligand endogenous danger signal, effectively enhanced humoral cellular responses in mice immunized by HBsAg. This study aimed to evaluate whether HS induces better against inactivated Hepatitis A or Rabies Vaccines, respectively, compared with adjuvants (e.g. Alum...
Abstract Background Nutrition service needs are huge in China. Previous studies indicated that personalized nutrition (PN) interventions were effective. The aim of the present study is to identify effectiveness and feasibility a novel PN approach supported by artificial intelligence (AI). Methods This two-arm parallel, randomized, controlled trial real world scenario. participants will be enrolled among who consume lunch at staff canteen. In Phase I, total 170 eligible assigned either...
Abstract Dietary intake may affect maternal health, but it remains unclear about puerperal dietary and its association with health. This study investigated the patterns their related factors postpartum weight retention (PPWR) in Chinese women. Participants were from mother–infant cohort study, which both mothers infants followed up childbirth to next 2 years, seven cities around China. Maternal derived by a food frequency questionnaire principal component analysis (PCA) within 1 month...
Anaemia is a public health problem that can lead to various harmful effects on physical and neurodevelopment in infants young children (IYC). This study aimed investigate trends of anaemia haemoglobin concentration among 6- 23-month-old Chinese IYC from 2016 2018. We used data the China Nutrition Improvement Project Children Poor Areas (CNIPCPA), conducted 142 national-level poor counties 20 provinces, autonomous regions, municipalities Our included 103,621 selected by stratified multistage...
Type 1 diabetes (T1D) is an autoimmune disorder characterised by the destruction of insulin-producing beta cells in pancreatic islets, resulting from a breakdown immunological tolerance. Currently, T1D treatment primarily relies on insulin replacement or immunosuppressive therapies. However, these approaches often have significant drawbacks, including adverse effects, high costs, and limited long-term efficacy. Consequently, there pressing need for innovative immunotherapeutic strategies...
OBJECTIVE To evaluate the effect of Yingyangbao(YYB) intervention in 6-23 months infants six poor counties from Shanxi, Hubei and Yunnan Provinces. METHODS Probability proportionate to size sampling method was used extract townships villages, random isometric select monitored infants. A baseline survey completed 2012. Yingyangbao delivered all through a registration system started 2013 then delivering has been continuously conducted according their age. The cross sectional sampled were...