A5102073175- Glass properties and applications
- Luminescence Properties of Advanced Materials
- Cancer-related molecular mechanisms research
- Dementia and Cognitive Impairment Research
- Animal Genetics and Reproduction
- Cancer Genomics and Diagnostics
- Eicosanoids and Hypertension Pharmacology
- Prostate Cancer Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Single-cell and spatial transcriptomics
- Plant Gene Expression Analysis
- Prostate Cancer Treatment and Research
- Autoimmune Neurological Disorders and Treatments
- High Altitude and Hypoxia
- Microbial Inactivation Methods
- Diet, Metabolism, and Disease
- Herpesvirus Infections and Treatments
- Phase-change materials and chalcogenides
- Random lasers and scattering media
- Microwave and Dielectric Measurement Techniques
- Peripheral Neuropathies and Disorders
- Hair Growth and Disorders
- Ferroptosis and cancer prognosis
- Skin Protection and Aging
- Lignin and Wood Chemistry
National Institute of Metrology
2024-2025
Kunming Medical University
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
China Agricultural University
2024
Huazhong University of Science and Technology
2024
Chongqing Medical University
2024
82th Hospital of Pla
2024
Tsinghua University
2024
Capital Medical University
2019-2023
Xuzhou Medical College
2023
Amnestic mild cognitive impairment (aMCI) is an early stage of Alzheimer's disease (AD). Regional homogeneity (ReHo) and amplitude low-frequency fluctuation (ALFF) are employed to explore spontaneous brain function in patients with aMCI. This study applied ALFF ReHo indicators analyze the neural mechanism aMCI by resting-state functional magnetic resonance imaging (rs-fMRI). Twenty-six were included assigned group. The other 26 healthy subjects as a control (HC) Rs-fMRI was performed for all...
Background: Computed tomography (CT) has been widely known to be the first choice for diagnosis of solid solitary pulmonary nodules (SSPNs). However, smaller SSPN is, less differential CT signs between benign and malignant SSPNs there are, which brings great challenges their diagnosis. Therefore, this study aimed investigate features small (≤15 mm) with different sizes. Methods: From May 2018 November 2021, data 794 patients were retrospectively analyzed. divided into groups, each group was...
Ischemic stroke (IS) is a life-threatening condition with limited treatment options; thus, finding the potential key genes for novel therapeutic targets urgently needed. This study aimed to explore candidate and pathways of brain microvessel endothelial cells (ECs) in IS by bioinformatics analysis.
Pancreatic cancer is a deadly disease with five-year overall survival rate of around 11%. Chemotherapy cornerstone in the treatment this malignancy, but intratumoral delivery chemotherapy drugs impaired by highly fibrotic tumor-associated stroma. Irreversible electroporation (IRE) an ablative technique for treating locally advanced pancreatic cancer. During typical IRE procedure, high-intensity electric pulses are released to kill tumor cells through irreversible disruption cytoplasm...
Abstract A group of dynamic-colour white fluorescences with various colour temperatures that can be applied to circadian lighting are achieved in Eu/Tb-codoped lithium-yttrium-aluminium-silicate (LYAS) glasses, which attributed the simultaneous generation three primary colours emitting from Eu 3+ (red), 2+ (blue) and Tb (green) by varying ultraviolet (UV) radiation wavelength. Fluorescence coordinates pass through whole region CIE x , y chromaticity diagram when UV excitation wavelength is...
The dysfunction of placenta is common in somatic cell nuclear transfer (SCNT) cloned cattle and would cause aberrant fetal development even abortion, which occurred with highest rate at the mid- to late gestation. However, mechanism abnormal placentas was unclear. To analyze transcriptome-wide characteristics SCNT cattle, mRNA, lncRNA miRNA placental cotyledon tissue day 180 after gestation were sequenced. A total 19,055 mRNAs, 30,141 lncRNAs 684 miRNAs identified. Compared control group,...
Background Altitude illness has serious effects on individuals who are not adequately acclimatized to high-altitude areas and may even lead death. However, the individualized mechanisms of onset preventive measures fully elucidated at present, especially relationship between altitude elements, which requires further in-depth research. Methods Fresh serum samples were collected from underwent health examinations two hospitals in Xining Sanya November 2021 December 2021. The blood zinc (Zn),...
Abstract Müller cells are the major supportive and protective glial in retina with important functions histogenesis synaptogenesis during development, maintenance of mature neurons as they show to secrete various cytokines manifest potentials self-renewal transdifferentiation into retinal following injury vertebrate retinas. The swine has a visual streak structure similar human macular where cone photoreceptors highly concentrated, thereby can serve better model for studying diseases...
Background: The histaminergic neurons in the hypothalamic tuberomammillary nucleus (TMN) have been suggested to play a vital role maintaining rising state. But neuronal types of TMN are debate and GABAergic remains unclear. Methods: In present study, we examined general anesthesia using chemogenetics optogenetics strategies regulate activity neurons. Results: results indicated that either chemogenetic or optogenetic activation mice decreased effect sevoflurane propofol anesthesia. contrast,...
Hypertension affects a large number of individuals globally and is common cause nephropathy, stroke, ischaemic heart disease other vascular diseases. While many anti-hypertensive medications are used safely effectively in clinic practice, controlling hypertensive complications solely by reducing blood pressure (BP) can be challenging. α-Mangostin, xanthone molecule extracted from the pericarp
Abstract Retinol has been widely added to skincare products due its ability promote the proliferation of skin keratinocytes and regulate cell collagen expression. While it is known harbors a myriad commensal bacteria, impact retinol on microbiome, as well role microbiome in mediating anti-aging properties retinol, remains poorly understood. In this study, we incorporated phenomics, metagenomics metabolomics explore human alterations during process mediated by potential interactions between...
Abstract The protein WWOX was reported to be involved in cancer progression via interaction with mTOR and DNA repair pathway. We previously noteworthy association of some single nucleotide polymorphisms (SNPs) pathways gastric (GCa) patients' survival. hypothesized that genetic variants gene could predict the survival GCa patients. By extracting from our ongoing genome‐wide study including 796 patients an Eastern Chinese population, we identified 51 out 1913 SNPs significantly associated...
In Er 3+ /Yb codoped Na 2 O-ZnO-PbO-GeO -TeO (NZPGT) glasses, effective ~1.5mm infrared (IR) emission was investigated under 980nm excitation. Judd-Ofelt intensity parameters Wt (t = 2, 4, 6) had been calculated to be 6.78´10-20, 1.54´10-20, and 1.17´10-20cm2, respectively. The IR full width at half maximum (FWHM) is 73nm, the stimulated cross-section (se) derived 7.53×10-21cm2. A figure of merit (FOM) as product FWHM´se adopted evaluate gain bandwidth. comparison FOM in different glasses...
In this 2 × 2, randomized, crossover bioequivalence study, two tablet preparations of helicidum were compared in 20 healthy Chinese male subjects. The drug was given a single dose three tablets (75 mg) and blood samples withdrawn during 12 h after administration. Helicidum separated analyzed using validated liquid chromatography-mass spectrum method. pharmacokinetic parameters determined from the plasma concentration-time profiles both formulations. primary calculated statistically to...