A5066712411- Tuberculosis Research and Epidemiology
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Blood properties and coagulation
- Antifungal resistance and susceptibility
- RNA Interference and Gene Delivery
- Cell Adhesion Molecules Research
- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Fungal Infections and Studies
- Diagnosis and treatment of tuberculosis
- Nail Diseases and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- T-cell and B-cell Immunology
- Esophageal Cancer Research and Treatment
- Methemoglobinemia and Tumor Lysis Syndrome
- Cancer Research and Treatments
- Glioma Diagnosis and Treatment
- Platelet Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Effects of Radiation Exposure
- Cardiac Imaging and Diagnostics
- Radiation Therapy and Dosimetry
Nanjing Medical University
2003-2023
Jiangsu Province Hospital
2003-2023
St. Michael's Hospital
2017
University of Toronto
2017
Canadian Blood Services
2017
Second Military Medical University
2014-2016
Nanjing University of Aeronautics and Astronautics
2016
Southeast University
2016
National Natural Science Foundation of China
2016
Shandong University
2015
The objective of this study was to investigate the clinical significance systemic inflammation score (SIS) and prognostic nutritional index (PNI) in esophageal squamous cell carcinoma (ESCC) patients who underwent esophagectomy. Records from 206 with histologically diagnosed ESCC esophagectomy at Qilu Hospital Shandong University January 2007 December 2008 were retrospectively reviewed. median disease-free survival (DFS) cohort 32.3 months 5-year DFS 34.5 %. overall (OS) 39.5 OS 40.8 We...
The incidence of cryptococcosis is increasing in non-immunocompromised patients. However, the evidence on proper management inadequate this population. We conducted multi-center real-world study pulmonary patients with different immune statuses, so as to provide practical for optimized clinical cryptococcosis, especially mild-to-moderate immunodeficient diseases patients.This a prospective observational study. data proven were collected and analyzed from 7 tertiary teaching hospitals Jiangsu...
Multidrug-resistant tuberculosis (MDR-TB) is a hard-to-treat disease with poor outcome of chemotherapy. In the present study, efficacy and safety recombinant human interleukin-2 (rhIL-2) were investigated in patients MDR-TB.Fifty culture-confirmed MDR-TB included. Twenty-five randomly assigned to trial group (injection 500 000 IU rhIL-2 once every other day at first, third, fifth seventh months addition standard multidrug therapy) another 25 control therapy. All monitored clinically, T-cell...
Abstract Background Current guidelines support different management of cryptococcosis between severely immunodeficient and immunocompetent populations. However, few studies have focused on patients with mild-to-moderate immunodeficiency. We performed this study to determine the clinical features pulmonary (PC) extrapulmonary (EPC) compared them among populations immune statuses appropriate public health threat. Methods All cases were reported by 14 tertiary teaching hospitals in Jiangsu...
It is urgent to find an optimised therapy regimen for the control of MDR-TB globally. This study aimed evaluate efficiacy and safety a combined rhIL-2 injection standard chemotherapy within 18-month duration in randomized controlled trial conducted 14 centres eastern China. From Jan. 2009 July. 2016, 271 cases were enrolled followed up two groups, 142 group while 129 group. Clinical efficacy, immune activity (Th1, Th17, Treg, IFN-γ, IL-17) among groups evaluated compared. After 24-month...
The expression of adhesion molecules and their related functions migration were investigated in peripheral blood mononuclear cells (PBMCs) to identify radiation-related changes dose-dependency. authors screened new biomarkers as radiation exposure dose indicators. Heparinized human was irradiated vitro with different doses γ-rays. levels the CD11a, CD11b, CD18, CD29, CD49d, CD54 on surface PBMC determined by flow cytometry at time points post-irradiation. ability PBMCs using an enzyme-linked...
Methemoglobin is an oxidative form of hemoglobin in erythrocytes. The authors' aim was to develop a new biological dosimeter based on methemoglobin assay. peripheral blood (of females or males) that exposed Co source (0.20 Gy min) quantified using enzyme-linked immunosorbent dose range 0.5-8.0 Gy. In time-course experiment, the time points 0, 0.02, 1, 2, 3, 7, 15, 21, and 30 d after 4-Gy irradiation heparinized were used. levels lysed erythrocyte pellet from irradiated males increased with...
Small interfering RNA (siRNA) is a potent, selective, and easily‐inducible method for blocking the expression of specifically targeted genes. siRNA reported to be more efficient than traditional therapy such as antisense oligonucleotides. However, use in allergen‐specific allergy has not yet been reported. Therefore, we attempted develop new using allergen‐pulsed dendritic cells (DCs) which CD40 silenced by siRNA. Bone marrow‐derived DCs were with pulsed ovalbumin (OVA). Following...
The aim of this work was to explore the effect nomogram mathematical model on treatment cerebral infarction complicated with nonvalvular atrial fibrillation (NVAF) and viral infection. data were scanned by a circular trajectory fan beam isometric scanning mode system (scanning system), speckle noise computed tomography (CT) images smoothed Lee filtering. 52 patients postoperative recurrent infection (RVI group) 248 without (NRVI selected for retrospective analysis. curve then analyzed...