A5080079858- Antimicrobial Resistance in Staphylococcus
- Phenothiazines and Benzothiazines Synthesis and Activities
- Radiopharmaceutical Chemistry and Applications
- Antifungal resistance and susceptibility
- X-ray Diffraction in Crystallography
- Orthopedic Infections and Treatments
- Hemoglobin structure and function
- Minerals Flotation and Separation Techniques
- Lanthanide and Transition Metal Complexes
- History and advancements in chemistry
- Chemical synthesis and alkaloids
- Advanced biosensing and bioanalysis techniques
- Synthesis and Biological Evaluation
- Porphyrin Metabolism and Disorders
- Antibiotic Resistance in Bacteria
- Crystallization and Solubility Studies
- Synthetic Organic Chemistry Methods
- Adsorption and biosorption for pollutant removal
- Radioactive element chemistry and processing
- Metal-Catalyzed Oxygenation Mechanisms
University of Wrocław
2021-2024
Increasing attention has been recently devoted to 89Zr(IV) and 68Ga(III) radionuclides, due their favorable decay characteristics for positron emission tomography (PET). In the present paper, a deep investigation is presented on Ga(III) Zr(IV) complexes with series of tri-(H3L1, H3L3, H3L4 desferrioxamine E, DFOE) tetrahydroxamate (H4L2) ligands. Herein, we describe rational design synthesis two cyclic complexing agents (H3L1 H4L2) bearing three four hydroxamate chelating groups,...
As multidrug-resistant bacteria are an emerging problem and threat to humanity, novel strategies for treatment diagnostics actively sought. We aim utilize siderophores, iron-specific strong chelating agents produced by microbes, as gallium ion carriers diagnosis, applying that Fe(III) can be successfully replaced Ga(III) without losing biological properties of the investigated complex, which allows molecular imaging positron emission tomography (PET). Here, we report synthesis, full solution...
A fluorescein-tagged iron(ii) cage complex was obtained in a moderate total yield using two-step synthetic procedure starting from its propargylamine-containing clathrochelate precursor. An 11-fold decrease fluorescence quantum is observed passing the given fluorescein-based dye to derivative. excitation energy transfer terminal fluorescent group of macrobicyclic molecule quasiaromatic highly π-conjugated framework can explain this effect. The kinetics hydrolysis acetyl groups acetylated...
The pathogenic fungus
In the Biological Inorganic Chemistry Group we are inspired to better understand metal ions acquisition and homeostasis in pathogenic bacteria, this review present three different approaches role of these processes. The growing importance a full understanding iron transport system pathogens prompted us study synthetic analogs siderophores, used as structural probes process uptake by microorganisms. ferrichrome biomimetic allowed efficient Fe(III) chelation under biological conditions were...