Huan Chen

ORCID: 0000-0003-1182-3144
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogenic Bacteria Studies
  • Plant Molecular Biology Research
  • Plant Parasitism and Resistance
  • Legume Nitrogen Fixing Symbiosis
  • Plant Stress Responses and Tolerance
  • Plant Virus Research Studies
  • Plant nutrient uptake and metabolism
  • Bacteriophages and microbial interactions
  • Ubiquitin and proteasome pathways
  • Plant tissue culture and regeneration
  • Photosynthetic Processes and Mechanisms
  • Genomics and Phylogenetic Studies
  • Synthesis and properties of polymers
  • Animal Disease Management and Epidemiology
  • Viral gastroenteritis research and epidemiology
  • Heat shock proteins research
  • Receptor Mechanisms and Signaling
  • Dendrimers and Hyperbranched Polymers
  • Machine Learning in Bioinformatics
  • Chromosomal and Genetic Variations
  • Biochemical and Structural Characterization
  • Viral Infectious Diseases and Gene Expression in Insects
  • Endoplasmic Reticulum Stress and Disease
  • Antimicrobial Peptides and Activities

Shanghai Jiao Tong University
2003-2025

Shanghai Cancer Institute
2023-2024

Renji Hospital
2023-2024

Beijing Academy of Science and Technology
2024

Nanjing Agricultural University
2017-2024

China Tobacco
2024

Tobacco Research Institute
2024

Jiangsu University of Science and Technology
2022-2024

Hubei University
2024

National Chung Hsing University
2024

10.1016/j.tplants.2021.11.013 article EN publisher-specific-oa Trends in Plant Science 2021-12-02

NPR1 (NONEXPRESSER OF PR GENES1) functions as a master regulator of the plant hormone salicylic acid (SA) signaling and plays an essential role in immunity. In nucleus, interacts with transcription factors to induce expression (PATHOGENESIS-RELATED) genes thereby promote defense responses. However, underlying molecular mechanism gene activation is poorly understood. Furthermore, despite importance immunity, regulation has not been extensively studied. Here, we show that SA promotes...

10.1104/pp.19.00124 article EN PLANT PHYSIOLOGY 2019-05-20

The phytohormone salicylic acid (SA) plays a pivotal role in plant defense against biotrophic and hemibiotrophic pathogens. NPR1 EDS1 function as two central hubs local systemic immunity. However, it is unclear how orchestrates gene regulation whether directly participates transcriptional reprogramming. Here, we show that synergistically activate pathogenesis-related (PR) genes defenses by forming protein complex recruiting Mediator. We discover functions an autonomous coactivator with...

10.1126/sciadv.abl7173 article EN cc-by-nc Science Advances 2021-11-05

It is well known that vitamin C could protect against influenza infection, but little about the mechanisms. This study aimed to investigate influence and possible mechanisms of on pneumonia induced by virus in stressed mice. Results showed restraint stress significantly increased mortality severity mice caused A/FM/1/47(H1N1) which was attenuated oral administration (125 250 mg/kg). Moreover, decreased expression susceptibility genes, including mitochondrial antiviral signaling (MAVS)...

10.1155/2015/675149 article EN cc-by BioMed Research International 2015-01-01

Abstract Crosstalk between plant hormone signaling pathways is vital for controlling the immune response during pathogen invasion. Salicylic acid (SA) and jasmonic (JA) often play important but antagonistic roles in responses of higher plants. Here, we identify a basic helix‐loop‐helix transcription activator, OsbHLH6, which confers disease resistance rice by regulating SA JA via nucleo‐cytosolic trafficking ( Oryza sativa ). OsbHLH6 expression was upregulated Magnaporthe oryzae infection....

10.1111/jipb.12922 article EN Journal of Integrative Plant Biology 2020-03-04

The phytocystatins of plants are members the cystatin superfamily proteins, which potent inhibitors cysteine proteases. Arabidopsis genome encodes seven phytocystatin isoforms (AtCYSs) in two distantly related AtCYS gene clusters. We selected AtCYS1 and AtCYS2 as representatives for each cluster then generated transgenic expressing GUS reporter under control promoter. These were used to examine expression at various stages plant development response abiotic stresses. Histochemical analysis...

10.1007/s00299-010-0876-y article EN cc-by-nc Plant Cell Reports 2010-06-04

Dehydration-responsive element-binding proteins (DREBs)regulate plant responses to environmental stresses. In the current study, transcription of DREB2C, a class 2 Arabidopsis DREB, was induced by superoxide anion propagator, methyl viologen (MV). The oxidative stress tolerance DREB2C-overexpressing transgenic plants significantly greater than that wild-type plants, as measured ion leakage and chlorophyll fluorescence under light conditions. transcriptional activity several ascorbate...

10.1007/s10059-012-2188-2 article EN cc-by-nc-sa Molecules and Cells 2012-01-28
Coming Soon ...