Bin Hua

ORCID: 0000-0003-1194-2231
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About
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Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Breast Cancer Treatment Studies
  • Water Quality and Pollution Assessment
  • Radioactive contamination and transfer
  • Power Systems and Technologies
  • Nuclear and radioactivity studies
  • Breast Lesions and Carcinomas
  • Soil Carbon and Nitrogen Dynamics
  • Water Quality Monitoring and Analysis
  • MRI in cancer diagnosis
  • MicroRNA in disease regulation
  • Advanced Neuroimaging Techniques and Applications
  • Heart Failure Treatment and Management
  • Cancer and Skin Lesions
  • Cancer-related molecular mechanisms research
  • Cardiac Health and Mental Health
  • Cancer Diagnosis and Treatment
  • Advanced Computational Techniques and Applications
  • Extracellular vesicles in disease
  • Simulation and Modeling Applications
  • Cardiovascular and exercise physiology
  • Smart Grid and Power Systems
  • Laser-Ablation Synthesis of Nanoparticles
  • High-Voltage Power Transmission Systems

Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2025

Beijing Hospital
2010-2024

Henan Agricultural University
2020-2024

Shanghai University of Traditional Chinese Medicine
2022-2024

Longhua Hospital Shanghai University of Traditional Chinese Medicine
2022-2024

Academy of Medical Sciences
2024

Fujian Medical University
2023

Shanghai Electric (China)
2009-2019

Imaging Center
2015

Jinan City People's Hospital
2015

Inhalable messenger RNA (mRNA) has demonstrated great potential in therapy and vaccine development to confront various lung diseases. However, few gene vectors could overcome the airway mucus intracellular barriers for successful pulmonary mRNA delivery. Apart from low delivery efficiency, nonnegligible toxicity is another common problem that impedes clinical application of many non-viral vectors. PEGylated cationic peptide-based vector a prospective approach enhance efficacy safety...

10.1080/10717544.2023.2219870 article EN cc-by-nc Drug Delivery 2023-06-19

Abstract Background Malignant progression is the major cause of poor prognosis in breast cancer (BC) patients. Plasma exosomal miRNAs have been reported to be involved tumor progression, but their roles BC remain unclear. Methods We performed plasma miRNA sequencing on 45 individuals, including healthy controls and nonmetastatic metastatic examined correlation between expression tissues exosomes patients by qRT‒PCR. The effects miR-361-3p cells were determined CellTiter-Glo, migration wound...

10.1186/s12967-024-04914-4 article EN cc-by Journal of Translational Medicine 2024-01-28

Background Identification of axillary lymph node (aLN) metastasis in breast cancer (BC) is important. Dual-energy computed tomography (DECT) a promising innovation the field CT. However, its role evaluating aLNs remains unclear. Purpose To investigate diagnostic performance DECT aLN BC patients. Material and Methods Data were prospectively collected from treatment-naïve patients who underwent for staging, ultrasound-guided biopsy suspicious aLNs, placement tissue marker pathology-positive...

10.1177/02841851251326469 article EN Acta Radiologica 2025-03-28

Analysis of the microRNA (miRNA) expression signature breast cancer based on RNA sequencing demonstrated that miR-361-3p was significantly upregulated in tissues. is a novel miRNA, and its role currently unclear. The aim present study to investigate functions carcinoma. In this study, it observed tissues higher compared with para-cancerous correlated advanced TNM stage, Ki-67 overexpression shorter disease-free survival. Overexpression promoted proliferation inhibited apoptosis cells....

10.1016/j.biopha.2020.109994 article EN cc-by-nc-nd Biomedicine & Pharmacotherapy 2020-02-25

Ultrasound-guided vacuum-assisted breast biopsy (VABB) is a common technique in surgery. To standardize this technique, the Chinese Society of Breast Surgery (CSBrS) re-evaluated quality evidence for clinical studies VABB, referring to grading recommendations assessment, development, and evaluation, developed Clinical Practice Guidelines biopsy: CSBrS 2021, accordance with Expert Consensus Operation Vacuum-assisted Biopsy (2017) combined data from practice surgery China, providing reference...

10.1097/cm9.0000000000001508 article EN cc-by-nc-nd Chinese Medical Journal 2021-06-01

The aim of this study was to investigate the diagnostic performance perfusion-related parameters intravoxel incoherent motion (IVIM) imaging for breast lesions, compared with dynamic contrast-enhanced magnetic resonance (DCE MRI).Fifty-nine patients both IVIM and subsequent DCE MRI were enrolled. Perfusion-related (perfusion fraction, f; pseudo-diffusion coefficient, D*), as well model-based model-free MRI, measured. Receiver operating characteristic curve analysis correlations between...

10.1097/rct.0000000000000661 article EN Journal of Computer Assisted Tomography 2017-08-03

Abstract As a crucial strategy for sustainable agricultural production, green manure–crop rotation can regulate soil nutrient cycling and decrease the reliance on nitrogen fertilizers. However, we still lack comprehensive understanding of changes in eco-enzyme activities, microbial metabolism limitations caused by leguminous rotation. Here, conducted field experiments across China to analyze extracellular enzyme specifically β-glucosidase (BG), N-acetyl-β-d-glucosaminidase (NAG), leucine...

10.1093/jpe/rtae065 article EN cc-by Journal of Plant Ecology 2024-07-26

Fibroadenoma (FA) is the most common type of breast lesion in young female individuals. Although malignant transformation FA rare, there evidence an association with carcinoma, particularly middle-aged females associated risk factors, such as a strong family history and/or BRCA-1/2 mutations. The current study presents case 44-year-old exhibiting lobular carcinoma situ (LCIS) arising within FA. Over previous 20 years, numerous lumps were detected patient's breasts, all which clinically...

10.3892/ol.2015.3488 article EN Oncology Letters 2015-07-14

This study aimed to evaluate the feasibility of applying carbon nanoparticles (CNs) visualize clip-marked metastatic nodes in combination with indocyanine green (ICG) and methylene blue (MB) as sentinel lymph node (SLN) tracers for targeted axillary dissection (TAD) after neoadjuvant therapy (NAT).This trial enrolled 40 patients node-positive breast cancer, 38 completed NAT surgery were included final analysis. Before or surgery, localized CNs by ultrasonography. After NAT, removed under...

10.1186/s12957-023-03120-8 article EN cc-by World Journal of Surgical Oncology 2023-07-21

High impedance faults (HIFs) have become a serious challenge of distribution networks which are difficult to be detected by the traditional protection scheme. And access distributed generations (DGs) makes fault description more difficult. With development distribution-level phasor measurement units (D-PMUs), visual and precise synchronous data could used for network. In this paper, Convolutional Neural Network (CNN) based HIF detection method is proposed. The extracted transient...

10.1049/cp.2019.0325 article EN 8th Renewable Power Generation Conference (RPG 2019) 2019-01-01

Objective To evaluate the hemostatic effect of hemocoagulase agkistrodon on surgical wound in breast cancer surgery. Methods Totally 60 patients undergoing surgery were enrolled this prospective,randomized,double-blinded,and controlled study. All met inclusion and exclusion criteria signed informed consent. Hemocoagulase (2 U) was injected 20 minutes before 4 24 hours after intervention group (n=30),whereas normal saline used instead control (n=30). The volume intraoperative bleeding,wound...

10.3881/j.issn.1000-503x.2017.02.004 article EN PubMed 2017-04-20

Papers reviewed herein provide a general overview of groundwater quality around the world in 2010. These include survey and assessment urban rural areas, impacts land uses on quality, with focus contamination, pollution prevention, remediation.

10.2175/106143011x13075599870018 article EN Water Environment Research 2011-01-01

Exercise training can improve exercise capacity, quality of life, and reduce hospitalization time in chronic heart failure (CHF) patients. Various protocols have been studied CHF, but there is no consensus on the optimal intensity for rehabilitation cardiac Therefore, systematic evaluation effects different intensities efficacy function life patients with CHF was done.

10.1097/md.0000000000028554 article EN cc-by-nc Medicine 2022-01-14

Purpose The aim of this study was to develop a widely accepted prognostic nomogram and establish risk-adapted PMRT strategy based on locoregional recurrence for pT1-2N1M0 breast cancer. Methods Materials A total 3,033 patients with cancer treated at 6 participating institutions between 2000 2016 were retrospectively reviewed. developed predicted recurrence-free survival (LRFS). propensity score-matched (PSM) analyses performed in model. Results With the median follow-up 65.0 months, 5-year...

10.3389/fonc.2020.588859 article EN cc-by Frontiers in Oncology 2020-12-11

This review is on the research literature published in 2012 related to physico‐chemical processes for water and wastewater treatment. The divided into seven sections, including coagulation/flocculation, sorption, filtration, sedimentation, flotation, oxidation, air stripping.

10.2175/106143013x13698672321823 article EN Water Environment Research 2013-10-01

This review is on the research literature published in 2013 related to physico‐chemical processes for water and wastewater treatment. The divided into seven sections, including coagulation/flocculation, filtration, oxidation, sedimentation, flotation, sorption process: removal of inorganics, organics.

10.2175/106143014x14031280667453 article EN Water Environment Research 2014-10-01

Abstract The distribution networks have more frequent and fast voltage fluctuations with the large‐scale access of distributed energy resources electric vehicles. Based on remote terminal unit (RTU) (DTU), traditional hierarchical control methods are difficult to achieve rapid global coordinated regulation due static modeling. For this purpose, paper proposes an integrated dynamic strategy which integrates objectives local secondary control. First, simplified models controllable equipment in...

10.1049/gtd2.12477 article EN cc-by-nc-nd IET Generation Transmission & Distribution 2022-04-13

Papers reviewed herein present a general overview of groundwater quality around the world in 2009. These include survey and assessment urban rural areas, impacts land uses on quality, with focus contamination, pollution prevention, remediation.

10.2175/106143010x12756668801978 article EN Water Environment Research 2010-01-01

Abstract Purpose Cutaneous metastasis (CM) accounts for 5–30% of patients with breast cancer (BC) and presents unfavorable response to treatment poor prognosis. A better understanding the molecular alterations involved in is essential, which would help identify diagnostic efficacy biomarkers CM. Materials : We retrospectively reviewed a total 13 histological or cytological diagnosis Of those patients, 8 had matched primary tumors Clinical information was extracted from medical records. All...

10.21203/rs.3.rs-3875283/v1 preprint EN cc-by Research Square (Research Square) 2024-01-23

<title>Abstract</title> Background Breast cancer (BC) is the most common malignancy in women, posing a serious health risk. Exosomal microRNA (miRNA) has emerged as promising biomarker. Despite its potential, research on exosomal miRNA BC remains limited. This study aims to identify plasma miRNAs for diagnosing BC. Methods Firstly, sequencing was conducted 45 patients and 5 healthy controls, followed by Differential Expression Analysis screen differentially expressed miRNAs. The diagnostic...

10.21203/rs.3.rs-4276021/v1 preprint EN Research Square (Research Square) 2024-04-29
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