- Bacteriophages and microbial interactions
- Microbial infections and disease research
- Spondyloarthritis Studies and Treatments
- Genomics and Phylogenetic Studies
- Psoriasis: Treatment and Pathogenesis
- Medical Research and Treatments
- Congenital heart defects research
- Rheumatoid Arthritis Research and Therapies
- International Maritime Law Issues
- Plant-based Medicinal Research
- Reproductive Biology and Fertility
- International Environmental Law and Policies
- Genetics, Aging, and Longevity in Model Organisms
- Traditional Chinese Medicine Analysis
- Environmental law and policy
- Head and Neck Surgical Oncology
- Urinary Tract Infections Management
- Inflammatory mediators and NSAID effects
- Neuropeptides and Animal Physiology
- Pelvic floor disorders treatments
- Pediatric Urology and Nephrology Studies
- Neurofibromatosis and Schwannoma Cases
- Paraquat toxicity studies and treatments
- Sexual Differentiation and Disorders
- Traditional Chinese Medicine Studies
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Guangdong Academy of Medical Sciences
2024
Southern Medical University
2024
Guangdong Provincial People's Hospital
2024
Qingdao University
2024
Affiliated Hospital of Qingdao University
2024
Yangzhou University
2009-2023
Jiangsu Second Normal University
2023
Second Military Medical University
2011-2020
Shanghai Changzheng Hospital
2011-2020
Background Identification of axillary lymph node (aLN) metastasis in breast cancer (BC) is important. Dual-energy computed tomography (DECT) a promising innovation the field CT. However, its role evaluating aLNs remains unclear. Purpose To investigate diagnostic performance DECT aLN BC patients. Material and Methods Data were prospectively collected from treatment-naïve patients who underwent for staging, ultrasound-guided biopsy suspicious aLNs, placement tissue marker pathology-positive...
Antimicrobial resistance (AMR) in clinically priority pathogensis now a major threat to public health worldwide. Phages are bacterial parasites that efficiently infect or kill specific strains and represent the most abundant biological entities on earth, showing great attraction as potential antibacterial therapeutics combating AMR. This review provides summary of phage-inspired strategies combat We firstly cover phage diversity, then explain principles therapy support use phages...
Urinary tract infections (UTIs) are a common health issue affecting individuals worldwide. Recurrent urinary (rUTI) pose significant clinical challenge, with limited understanding of the underlying mechanisms. Recent research suggests that urobiome, microbial community residing in tract, may play crucial role development and recurrence infections. However, specific virulence factor genes (VFGs) driven by urobiome contributing to infection remain poorly understood. Our study aimed investigate...
Ankylosing spondylitis (AS) is a highly heritable common inflammatory arthritis that targets the spine and sacroiliac joints of pelvis, causing pain stiffness leading eventually to joint fusion. Although previous studies have shown strong association IL23R with AS in white Europeans, similar East Asian populations no variants IL23R, suggesting either role or rare genetic contribute. The present study was undertaken screen identify associated Han Chinese.A 170-kb region containing its...
P1 -like phage-plasmids (PPs) are important gene vehicles in isolated pathogens. In this study, we conducted genome-wide and cross-species analysis of antimicrobial resistance genes (ARGs) from 35 ARG-positive P1-like PPs. LS-BSR reveal that PPs had common 7 highly variable regions carried 48 different ARG subtypes. The most prevalent groups were the colistin mcr-1 a class 1 integron. Analysis flanking sequences indicated an "IS30-mcr-1-ORF-IS30" as core cluster. particular, found mcr-1-...
Abstract Antibiotic-resistant bacteria are current threats to available antibiotic therapies, and this has renewed interest in the therapeutic use of phage as an alternative. However, development resistance led unsuccessful outcomes. In study, we applied training minimize bacterial improve treatment outcome by adapting their target hosts during co-evolution. We isolated characterized a novel Pseudomonas aeruginosa N4-like lytic (PWJ) from wastewater Yangzhou, China. PWJ is double-stranded...
OBJECT: Surgical removal of anterior clinoidal meningiomas (ACMs) remains a challenge because its complicated relationship with surrounding meninges, major arteries and cranial nerves. This study aims to define the meningeal structures around clinoid process (ACP) surgical implications. METHODS: Five dry skulls nineteen cadavers were used anatomical study. Cadavers prepared as transverse, coronal sagittal plastinated sections, architecture ACP was studied dissecting microscopy confocal...
Abstract Telomere shortening, a marker of cellular aging and genomic instability, has been epidemiologically linked to an increased risk various cardiovascular diseases (CVDs). However, shared genetic determinants involved in these associations remain unclear. We composed atlas the between leukocyte telomere length (LTL) six major CVDs by investigating elements, encompassing SNPs, genes, biological pathways, protein targets with pleiotropic implications. Extensive overlaps beyond...
Objective To evaluate the elimination effect of gastric lavage (GL) in swine model paraquat (PQ) poisoning by using determination PQ plasma concentration. Methods A total 17 healthy female domestic were randomly divided into group (n=6), PQ+ 1 h GL (n=6) and 6 (n=5). A dose 60 mg /kg 40% solution was administered all animals through tube. Swine treated with 20 L warm water at after ingestion PQ, respectively. Vital signs concentration monitored continuously for 24 h. LC-MS device used...