A5017348203- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Peripheral Artery Disease Management
- Social and Educational Sciences
- Education, Healthcare and Sociology Research
- Clinical practice guidelines implementation
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- S100 Proteins and Annexins
- Clinical Reasoning and Diagnostic Skills
- Intracranial Aneurysms: Treatment and Complications
- Glioma Diagnosis and Treatment
- Trauma and Emergency Care Studies
- Sepsis Diagnosis and Treatment
- Cardiovascular and Diving-Related Complications
- Healthcare Systems and Practices
- Vascular Malformations Diagnosis and Treatment
- Orthopaedic implants and arthroplasty
- Cardiac Arrest and Resuscitation
Oslo University Hospital
2014-2025
Brigham Young University
2024
University Hospital of North Norway
2018
Stiftelsen Norsk Luftambulanse
2015-2018
Nord University
2018
Haukeland University Hospital
2018
Vejle Sygehus
2017-2018
In-Q-Tel
2012
Smerteklinikken
2011
University of Oslo
2008
Left heart catheterization carries a risk for cerebral complications. The aims of this prospective study were to determine the frequency and composition catheterization-related microemboli detect morphological changes acute cognitive impairment due catheterization.Forty-seven unselected patients undergoing elective left catheterization, either by transradial or transfemoral access, monitored using multifrequency transcranial Doppler. Cerebral magnetic resonance imaging (MRI) with...
National Institutes of Health Stroke Scale (NIHSS) is the most validated clinical scale for stroke recognition, severity grading, and symptom monitoring in acute care hospital settings. Numerous modified prehospital scales exist, but these contain less information lack compatibility with in-hospital scales. In this real-life study, we aimed to investigate if NIHSS conducted by paramedics field a feasible accurate diagnostic tool.This prospective cohort study part Treat-NASPP (Treat-Norwegian...
This article summarises recommendations for acute management of stroke by the European Stroke Initiative (EUSI), on behalf Council (ESC), Neurological Society (ENS), and Federation Societies (EFNS).
Alteplase is the only approved thrombolytic agent for acute ischaemic stroke. The overall benefit from alteplase substantial, but some evidence indicates that also has negative effects on brain. Tenecteplase may be more effective and less harmfull than alteplase, large randomised controlled phase 3 trials are lacking. Norwegian Stroke Trial (NOR-TEST) aims to compare efficacy safety of tenecteplase vs. alteplase. NOR-TEST a multi-centre PROBE (prospective randomised, open-label, blinded...
During a 2-week period, we have encountered five cases presenting with the combination of cerebral venous thrombosis (CVT), intracerebral hemorrhage and thrombocytopenia. A clinical hallmark was rapid severe progression disease in spite maximum treatment efforts, resulting fatal outcome for 4 out 5 patients. All had received ChAdOx1 nCov-19 vaccine 1–2 weeks earlier developed characteristic syndrome thereafter. The progressive course high fatality rate CVT thrombocytopenia such cluster...
Abstract Background Rapid diagnosis and treatment of stroke is important for good outcome. In some cases, patients with ischemic arrive at hospital too late reperfusion therapy. This may be the case especially in rural areas where time spent during transport delay or even preclude thrombolytic after arrival. We aimed to estimate extent clinical relevance this problem Norwegian population. Methods collected data all reported acute strokes years 2017 2018. Transport times from home were...
Abstract Background Acute stroke treatment in mobile units (MSU) is feasible and reduces time‐to‐treatment, but the optimal staffing model unknown. We wanted to explore if integrating thrombolysis of acute ischemic (AIS) an anesthesiologist‐based emergency medical services (EMS) time‐to‐treatment safe. Methods A nonrandomized, prospective, controlled intervention study. Inclusion criteria: age ≥18 years, nonpregnant, symptoms with onset ≤4 h. The MSU inspired by Norwegian Helicopter...
Abstract Background The endovascular treatment procedure in tandem occlusions (TO) is complex compared to single occlusion (SO) and optimal management remains uncertain. aim of this study was identify clinical procedural factors that may be associated efficacy safety the TO compare functional outcome SO stroke patients. Methods This a retrospective center medium (MeVO) large vessel (LVO) anterior circulation. Clinical, imaging, interventional data were analyzed predictive for symptomatic...
Background: Early diagnosis and triage of patients with ischemic stroke is essential for rapid reperfusion therapy. The prehospital delay may be substantial from rural districts often arrive at their local hospital too late disability-preventing thrombolytic therapy due to prolonged transport times. Methods: Hallingdal District Medical Centre (HDMC) located in a area Norway equipped computed tomography (CT) scanner. We established emergency pathways CT imaging treatment acute HDMC. During...
In acute stroke, thromboembolism or spontaneous hemorrhage abruptly reduces blood flow to a part of the brain. To limit necrosis, rapid radiological identification pathological mechanism must be conducted allow initiation targeted treatment. The aim Norwegian Acute Stroke Prehospital Project is determine if anesthesiologists, trained in prehospital critical care, may accurately assess cerebral computed tomography (CT) scans mobile stroke unit (MSU).In this pilot study, 13 anesthesiologists...
Background and purpose It is essential to diagnose ischaemic stroke as soon possible after symptom onset, so that thrombolytic treatment can be initiated quickly possible. This might greatly facilitated if cerebral CT could carried out in a pre‐hospital setting. The aim of this study was evaluate anaesthesiologists, who Norway provide medical care, trained assess scans exclude radiological contraindications for treatment. Methods Thirteen anaesthesiologists attended an 8‐h course acute...
Ultrasound accelerates thrombolysis with tPA (sonothrombolysis). in the absence of also clot break-up (sonolysis). Adding intravenous gaseous microbubbles may potentiate effect ultrasound both sonothrombolysis and sonolysis. The Norwegian Sonothrombolysis Acute Stroke Study aims a pragmatic approach to assess safety contrast enhanced treatment unselected acute ischaemic stroke patients. patients ≥18 years, or without visible arterial occlusion on computed tomography angiography (CTA)...
Cerebral revascularization in acute stroke requires robust diagnostic tools close to symptom onset. The quantitative National Institute of Health Stroke Scale (NIHSS) is widely used in-hospital, whereas shorter and less specific scales are the prehospital field. This study explored accuracy potential clinical benefit using NIHSS prehospitally.Thirteen anesthesiologists trained critical care enrolled patients with suspected a mobile unit. was completed twice phase: first prehospitally then by...
Abstract Background and aims Whereas high-level evidence has been proven for safety efficacy of endovascular treatment (EVT) in large vessel occlusion (LVO) stroke, the EVT medium (MeVO) both sexes different age groupremains to be answered. The aim this study was evaluate importance clinical technical parameters, focusing on sex, procedural factors, functional outcome primary MeVO (pMeVO) strokes. Methods 144 patients with pMeVO MCA territory from Oslo Acute Reperfusion Stroke Study (OSCAR)...
Subarachnoid hemorrhage (SAH) is associated with higher mortality in the acute phase than other stroke types. There a particular risk of early and devastating re-bleeding. Patients therefore need urgent assessment neurosurgical department, shorter time from symptom onset to diagnosis better. The Norwegian Acute Stroke Pre-hospital Project (NASPP) has developed Mobile Unit (MSU) model, which staffed anesthesiologists also trained pre-hospital clinical patients interpretation computerized...
Abstract Introduction: The aim of this prospective study was to determine the frequency and composition cerebral microemboli in a paediatric population during transcatheter atrial septal defect closure. Methods: Multi-frequency transcranial Doppler used detect microembolic signals middle artery 24 patients. Embolic were automatically identified differentiated according their composition, gaseous or solid. procedure divided into five periods: right cardiac catheterisation; left pulmonary...
Early access to hospital for diagnosis and treatment is strongly recommended patients with acute stroke. Unfortunately, prehospital delay frequently occurs. The aim of the current study was gain in-depth insight into patient experience behavior in phase a stroke.We conducted qualitative interviews purposive sample 11 six witnesses within four weeks post were audio recorded, transcribed, analyzed utilizing Systematic Text Condensation.The material classified according two main categories each...
The aims of this study were firstly to determine prevalence, frequency, and clinical significance cerebral microemboli in an unselected acute ischemic stroke population secondly examine how information may improve subtype classification.We intended perform transcranial Doppler (TCD) microembolus monitorings the middle artery (MCA) symptomatic hemisphere for 45 min 120 consecutive patients with internal carotid territory ischemia. first examination was performed within 72 h from start...