Avan Aihie Sayer
A5088063654- Nutrition and Health in Aging
- Frailty in Older Adults
- Body Composition Measurement Techniques
- Birth, Development, and Health
- Obesity, Physical Activity, Diet
- Chronic Disease Management Strategies
- Nutritional Studies and Diet
- Health Systems, Economic Evaluations, Quality of Life
- Bone health and osteoporosis research
- Muscle Physiology and Disorders
- Cerebral Palsy and Movement Disorders
- Hip and Femur Fractures
- Diet and metabolism studies
- Muscle metabolism and nutrition
- Health disparities and outcomes
- Physical Activity and Health
- Clinical Nutrition and Gastroenterology
- Obesity and Health Practices
- Geriatric Care and Nursing Homes
- Genetics, Aging, and Longevity in Model Organisms
- Balance, Gait, and Falls Prevention
- Child Nutrition and Feeding Issues
- Pregnancy and preeclampsia studies
- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
Newcastle upon Tyne Hospitals NHS Foundation Trust
2016-2025
NIHR Newcastle Biomedical Research Centre
2016-2025
Newcastle University
2016-2025
Cumbria Northumberland Tyne and Wear NHS Foundation Trust
2023-2025
University of Newcastle Australia
2016-2024
Clinical Research Institute
2024
Newcastle upon Tyne Hospital
2018-2024
National Health Service
2018-2024
University of Southampton
2012-2021
Centre for Life
2021
in 2010, the European Working Group on Sarcopenia Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances identifying and caring for people with sarcopenia. In early 2018, met again (EWGSOP2) update original order reflect scientific clinical evidence has built over last decade. This paper presents our updated findings. increase consistency of research design, diagnoses ultimately, care is muscle disease (muscle failure) rooted adverse changes accrue across...
Background Several studies in older people have shown that grip strength predicts all-cause mortality. The mechanisms are unclear. Muscle declines with age, accompanied by a loss of muscle mass and an increase fat, but the role body composition plays association between mortality has been little explored. We investigated relation strength, composition, cause-specific total 800 men women aged 65 over.
Background:chronological age is widely used as a marker of frailty in clinical practice. However there can be wide variation between individuals similar age. Grip strength powerful predictor disability, morbidity and mortality which has been number scores but not single frailty. Objective: to investigate the potential grip older people chronological Design: cross-sectional study with prospective collection data. Setting: North Hertfordshire, UK. Subjects: 717 men women, aged 64–74, born...
falls are a major cause of disability and death in older people. Women more likely to fall than men, but little is known about whether risk factors for differ between the sexes. We used data from English Longitudinal Study Ageing investigate prevalence by sex examine cross-sectionally sex-specific associations range potential likelihood falling. participants were 4,301 men women aged 60 over who had taken part 2012–13 survey Ageing. They provided information sociodemographic, lifestyle...
OBJECTIVE Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin levels are associated with impaired β-cell function, raised glucose levels, resistance, type 2 diabetes (T2D). Studies the processing pathway could provide new insights about T2D pathophysiology. RESEARCH DESIGN AND METHODS We have conducted meta-analysis genome-wide association tests ∼2.5 million genotyped or imputed single nucleotide polymorphisms (SNPs) fasting in 10,701 nondiabetic adults...
Introduction: sarcopenia is associated with adverse health outcomes. The aim of this study was to describe the prevalence in community-dwelling older people UK using European Working Group on Sarcopenia Older People (EWGSOP) consensus definition. Methods: we applied EWGSOP definition 103 men participating Hertfordshire Study (HSS) both lowest third dual-energy X-ray absorptiometry (DXA) lean mass (LM) and skin-fold-based fat-free (FFM) as markers low muscle mass. We also used FFM approach...
There is growing recognition that the complications associated with type 2 diabetes may translate into functional impairment in older people (1). This reflect a link between metabolic and mechanical functions of muscle. However, possibility glucose tolerance physical function extends to without has not been previously considered. The objective this study was determine whether there relationship among tolerance, muscle strength, men women diabetes. A cross-sectional survey within cohort...
Objective: to investigate the relationship between grip strength and health-related quality of life (HRQoL). Design: cross-sectional survey within a cohort study design. Setting: county Hertfordshire in UK. Participants: total 2,987 community-dwelling men women aged 59–73 years age. Measurements: was used as marker sarcopaenia measured using Jamar dynamometer. HRQoL assessed eight domain scores Short Form-36 (SF-36) questionnaire, subjects lowest sex-specific fifth distribution were...
Objective: to examine the prevalence of frailty and disability in people aged 60 over proportion those with disabilities who receive help or use assistive devices. Methods: participants were 5,450 from English Longitudinal Study Ageing. Frailty was defined according Fried criteria. Participants asked about difficulties mobility other everyday activities. Those whether they received used Results: overall weighted 14%. Prevalence rose increasing age, 6.5% 60–69 years 65% 90 over. occurred more...