Nicolaas H. Sperna Weiland

ORCID: 0000-0003-1305-1846
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About
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Research Areas
  • Climate Change and Health Impacts
  • Cardiac, Anesthesia and Surgical Outcomes
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Hemodynamic Monitoring and Therapy
  • Optical Imaging and Spectroscopy Techniques
  • Anesthesia and Neurotoxicity Research
  • Healthcare cost, quality, practices
  • Healthcare and Environmental Waste Management
  • Anesthesia and Sedative Agents
  • Health Systems, Economic Evaluations, Quality of Life
  • Infection Control and Ventilation
  • Neurosurgical Procedures and Complications
  • COVID-19 and healthcare impacts
  • Meta-analysis and systematic reviews
  • Environmental Education and Sustainability
  • Air Quality and Health Impacts
  • Climate Change Communication and Perception
  • Spaceflight effects on biology
  • Recycling and Waste Management Techniques
  • Respiratory Support and Mechanisms
  • Airway Management and Intubation Techniques
  • Heart Rate Variability and Autonomic Control
  • Intensive Care Unit Cognitive Disorders
  • Urban Green Space and Health
  • Marine and Offshore Engineering Studies

University of Amsterdam
2018-2025

Amsterdam University Medical Centers
2018-2025

RWTH Aachen University
2025

University Hospital Bonn
2025

Universitätsklinikum Würzburg
2025

University of Turin
2024

University of Novi Sad
2024

Sapienza University of Rome
2024

European University
2024

University of Southern Denmark
2024

Climate change is a defining issue for our generation. The carbon footprint of clinical practice accounts 4.7% European greenhouse gas emissions, with the Union ranking as third largest contributor to global healthcare industry's footprint, after United States and China. Recognising importance urgent action, Society Anaesthesiology Intensive Care (ESAIC) adopted Glasgow Declaration on Environmental Sustainability in June 2023. Building this initiative, ESAIC Committee now presents consensus...

10.1097/eja.0000000000001942 article EN European Journal of Anaesthesiology 2024-01-18

The Covid-19 pandemic led to threatening shortages in healthcare of medical products such as face masks. Due this major impact on our society an initiative was conducted between March and July 2020 for reprocessing masks from 19 different hospitals. This exceptional opportunity used study the costs carbon footprint reprocessed relative new disposable aim is conduct a Life Cycle Assessment (LCA) assess compare climate change disposed versus In total 18.166 high quality FFP2 were through steam...

10.1038/s41598-021-97188-5 article EN cc-by Scientific Reports 2021-09-03

Purpose of review The excessive growth the health sector has created an industry that, while promoting health, is now itself responsible for a significant part global environmental pollution. crisis caused by climate change urges us to transform healthcare into sustainable industry. This aims raise awareness about this issue and provide practical evidence-based recommendations anaesthesiologists. Recent findings We offer seven anaesthesiologists that want their own practice. Summary offers...

10.1097/aco.0000000000001243 article EN cc-by Current Opinion in Anaesthesiology 2023-01-23

Anaesthetic gases account for ∼3% of the carbon footprint entire healthcare sector and up to 63% emissions originating from surgical care. Transitioning predominant use total intravenous anaesthesia (TIVA) has been proven a safe effective strategy reduce this footprint, yet its adoption slow in most countries. Interventions at national level have limited regulatory action (e.g. banning desflurane) publication nonbinding recommendations best practices. We describe new approach that we used...

10.1016/j.bja.2024.11.049 article EN cc-by British Journal of Anaesthesia 2025-01-01

Health systems urgently need to transform and build resilience against the consequences of climate change.1WHOOperational framework for building resilient health systems. World Organization, Geneva2015Google Scholar The future current workforces have an essential role in this process and, effectively capacitate them, researchers called inclusion planetary medical curriculum.2Wellbery C Sheffield P Timmireddy K Sarfaty M Teherani A Fallar R It's time schools introduce change into their...

10.1016/s2542-5196(22)00316-3 article EN cc-by-nc-nd The Lancet Planetary Health 2023-01-01

Taking the best possible care of our patients has been main driver to constantly develop specialty and pushing boundaries what 50, 20 or 10 years ago was beyond imagination. Clinical research paved way for these improvements. Large international observational multicentre studies randomised controlled trials have enabled translation promising findings into improved patient care. However, serious challenges are piling up on horizon. Europe is facing a dramatic healthcare workforce crisis.1 The...

10.1097/eja.0000000000002105 article EN European Journal of Anaesthesiology 2025-01-02

ABSTRACT Introduction The ethical obligation to reduce the environmental impact of healthcare systems prompts an exploration if and when concerns should be integrated into clinical decision‐making. In this study, we aimed elucidate patients' attitudes regarding provision information in decision‐making identify preferred approaches for integrating these considerations patient–provider consultations. Methods This interview study served as in‐depth follow‐up a survey on gynaecological...

10.1111/hex.70155 article EN cc-by Health Expectations 2025-01-19

To maintain adequate perfusion, cerebral blood flow (CBF) is preserved by changes in cerebrovascular resistance (CVR) inversely related to fluctuations mean arterial pressure (MAP). It has been hypothesised that during progressive hypotension, a lower limit of autoregulation (LLCA) reached beyond which dilation becomes exhausted and CBF starts decrease together with BP. We tested this hypothesis assessing CVR above below the LLCA. Radial pressure, thermodilution cardiac output (CO), middle...

10.1016/j.bja.2024.12.037 article EN cc-by British Journal of Anaesthesia 2025-02-01

This life cycle assessment compares the environmental footprint of reusable surgical head covers with single-use disposable covers.

10.1001/jamasurg.2023.3863 article EN JAMA Surgery 2023-09-06

The urgency for action on climate change is regarded as the defining issue of our time. Planetary health education prepares future healthcare professionals to promote planet, including sustainable healthcare. This has potential benefits system, patients, community, and environment. However, many educators are not confident in explaining inspiring students deans educational staff report challenges when integrating planetary into education. roadmap presented this paper uses evidence from...

10.1080/0142159x.2022.2137015 article EN Medical Teacher 2022-11-17

Despite a rise in blood pressure, cerebral oxygenation decreases following phenylephrine administration, and we hypothesised that reduces by activating α1 receptors. We studied patients on cardiopulmonary bypass during constant flow. Phenylephrine raised mean arterial pressure (α1 -mediated) from (SD) 69 (8) mmHg to 79 mmHg; p = 0.001, vasopressin (V1 mediated) 83 (6) 0.001. Both drugs elicited comparable decrease 61 (7)% 60 (7)%; 0.023 (8)% 59 (8)%; 0.022, respectively. This implies after...

10.1111/anae.13631 article EN Anaesthesia 2016-10-17

Classically, cerebral autoregulation (CA) entails blood flow (CBF) remaining constant by cerebrovascular tone adapting to fluctuations in mean arterial pressure (MAP) between ∼60 and ∼150 mmHg. However, this is not an on-off mechanism; previous work has suggested that vasomotor proportionally related CA function. During propofol-based anaesthesia, there vasoconstriction, static remains intact. Sevoflurane-based anaesthesia induces vasodilation attenuates dose-dependently. It unclear how...

10.1097/eja.0000000000001798 article EN cc-by European Journal of Anaesthesiology 2023-01-19
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