Li An

ORCID: 0000-0003-1312-1904
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About
Contact & Profiles
Research Areas
  • Asthma and respiratory diseases
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Respiratory and Cough-Related Research
  • Cancer Cells and Metastasis
  • Shoulder and Clavicle Injuries
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Healthcare Systems and Reforms
  • Lung Cancer Research Studies
  • Occupational and environmental lung diseases
  • Pneumothorax, Barotrauma, Emphysema
  • Retinal and Optic Conditions
  • Shoulder Injury and Treatment
  • Pericarditis and Cardiac Tamponade
  • Immune Response and Inflammation
  • Mechanical Circulatory Support Devices
  • Biochemical and Molecular Research
  • Click Chemistry and Applications
  • Fibroblast Growth Factor Research
  • Cardiac Arrest and Resuscitation
  • Elbow and Forearm Trauma Treatment
  • Metastasis and carcinoma case studies
  • Bone and Dental Protein Studies
  • Pleural and Pulmonary Diseases
  • 3D Shape Modeling and Analysis
  • Immune cells in cancer

Beijing Chao-Yang Hospital
2017-2025

Capital Medical University
2017-2025

University of Shanghai for Science and Technology
2025

Xuzhou Medical College
2024

Guangzhou Medical University
2024

First Affiliated Hospital of Gannan Medical University
2024

WuXi AppTec (China)
2023

Shanghai Pulmonary Hospital
2022

Beijing Institute of Neurosurgery
2022

China-Japan Friendship Hospital
2020

Objective: To master the status of ophthalmic human resource allocation and service delivery at county level in Mainland China, to provide basis for strengthening construction grassroots personnel team formulating feasible medium long-term eye health plans. Methods: All medical institutions that provided or above were investigated by online reporting. This study only included level. Descriptive statistics used. Results: Three thousand three hundred fifty-nine included, which 1 463 hospitals...

10.3760/cma.j.issn.0412-4081.2018.12.011 article EN PubMed 2018-12-11

Patients with features of both asthma and chronic obstructive pulmonary disease (COPD) are seen commonly in the clinic but less is known general population. We investigated prevalence heterogeneity COPD concomitant Chinese adult population.COPD was defined as post-bronchodilator ratio forced expiratory volume 1s (FEV1) to vital capacity than lower limits normal. either diagnosed by self-reported physician-diagnosis or presence current wheeze, high bronchodilator response (HBR) an increase...

10.3389/fmed.2022.876240 article EN cc-by Frontiers in Medicine 2022-05-06

Abstract Background Pleural effusion caused by fibrosing mediastinitis is rarely reported. This study aimed to summarize the clinical manifestations, diagnosis and treatment of transudative pleural due mediastinitis. Methods Medical records follow-up data 7 patients with in Beijing Chaoyang Hospital between May 2014 Feb 2018 were retrospectively analyzed. Results These included 4 males 3 females, an average age (64 ± 9) years. There left-sided effusions, 2 right-sided effusions bilateral...

10.1186/s13019-024-02972-9 article EN cc-by Journal of Cardiothoracic Surgery 2024-07-26

Circulating tumor cells (CTCs) provide a unique resource to decipher cell molecular properties of lung cancer. However, the clinicopathologic and radiological features associated with CTCs in different cancer subtypes remain poorly characterized. The aim this study was explore clinicopathological subtypes.

10.21037/tlcr-24-955 article EN Translational Lung Cancer Research 2024-11-01

Abstract The Kirsten rat sarcoma viral oncogene homolog (KRAS) is mutated in approximately 25% of all human cancers and known to be a major player promoting maintaining tumorigenesis through the RAS-MAPK pathway. Activating mutations KRAS increase ability for GTP-loading, making it difficult displace, thus constitutively activate downstream MAPK pathway promote cancer formation. Fortunately, revolutionary strategy use covalent allosteric inhibitors that target shallow pocket on surface has...

10.1158/1538-7445.am2023-4984 article EN Cancer Research 2023-04-04

<b>Objectives:</b> Occupational and environmental exposure to asbestos was able induce asbestosis as well pleural abnormalities after a prolonged latency period. This study is aimed investigate the radiographic characteristics of different stages in patients which showed difference with other interstitial pneumonias. <b>Methods:</b> A cohort newly diagnosed 281 over period eight years single center were evaluated. Clinical data collected from clinical charts. Radiographs reviewed by experts...

10.1183/1393003.congress-2017.pa1522 article EN 2017-09-01
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