A5100606298- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Ion channel regulation and function
- Pulmonary Hypertension Research and Treatments
- Healthcare Systems and Reforms
- Cancer, Hypoxia, and Metabolism
- Global Health Care Issues
- Pediatric health and respiratory diseases
- High Altitude and Hypoxia
- Neonatal Respiratory Health Research
- Global Maternal and Child Health
- Cytokine Signaling Pathways and Interactions
- Immune Response and Inflammation
- Nitric Oxide and Endothelin Effects
- Cancer-related molecular mechanisms research
- Neuroscience of respiration and sleep
- Heme Oxygenase-1 and Carbon Monoxide
- Health disparities and outcomes
- IL-33, ST2, and ILC Pathways
- Respiratory Support and Mechanisms
- Respiratory and Cough-Related Research
- Mitochondrial Function and Pathology
- Inflammatory mediators and NSAID effects
- Immune Cell Function and Interaction
- Obstructive Sleep Apnea Research
Xi'an Jiaotong University
2015-2025
Institute of High Energy Physics
2024
Chinese Academy of Sciences
2024
Harbin Engineering University
2023
National Clinical Research
2022
Tongji Hospital
2012-2022
Huazhong University of Science and Technology
2012-2022
Liverpool School of Tropical Medicine
2019
Jinan University
2014-2018
Peking University
2017
Equity is one of the major goals China's recent health system reform. This study aimed to evaluate equality distribution resources and services between hospitals primary care institutions. Data this were drawn from China Health Statistical Year Books. We calculated Gini coefficients based on population size geographic size, respectively, for indicators: number institutions, workers beds; concentration index (CI) per capita outpatient visits annual hospitalization rates. The against ranged...
Rationale: Activation of type 2 cytokine pathways plays a central role in large subset subjects with asthma. Th2-high and Th2-low asthma have distinct clinical, pathologic, molecular phenotypes respond differently to therapy. The factors that initiate responses some are unknown.Objectives: To determine whether expression epithelial cytokines IL-25, IL-33, thymic stromal lymphopoietin associated predict response inhaled corticosteroid (ICS) asthma.Methods: We analyzed pulmonary function...
A multitude of epidemiological studies have shown that ambient fine particulate matter 2.5 (diameter < 2.5um; PM2.5) was associated with increased morbidity and mortality chronic obstructive pulmonary disease (COPD). However, the underlying mechanisms not yet been elucidated. We conducted this study to investigate role PM2.5 in development COPD mechanisms.We firstly a cross-sectional Chinese han population observe effects on morbidity. Then, vitro, we incubated human bronchial epithelial...
Chronic obstructive pulmonary disease (COPD) is an inflammatory lung characterized by cell activation and the release of mediators. Interleukin-33 (IL-33) plays a critical role in various immunological pathologies, but evidence for its COPD lacking. This study aimed to investigate expression IL-33 determine whether participates initiation progression COPD. Levels serum receptors were measured ELISA, levels IL-33, ST2, IL-1 receptor accessory protein elevated patients with compared control...
Although there are over 1.34 billion Chinese in the world, nationwide spirometric reference values for unavailable, which is usually based on Caucasian conversion. The aim of this study was to establish with a national wide sample. We enrolled healthy non-smokers 24 centers Northeast, North, Northwest, Southwest, South, East and Central China from January 2007 June 2010. Spirometry performed according American Thoracic Society European Respiratory guidelines. Reference equations were...
Policy interventions have been taken to protect households from facing unpredictable economic changes that may cause catastrophe in China. This study aims estimate the change of overall proportion incurring catastrophic health care expenditure (CHE) and its income-related inequality rural areas Shaanxi Province 2008 2013.The data were drawn National Household Health Service Surveys conducted years 2013. In total, 3,217 13,085 2013 selected for analysis. A "Capacity pay" approach was used...
Accelerated population ageing brings about unprecedented challenges to the health system in China. This study aimed measure prevalence and income-related inequality of depressive symptoms, also identify determinants symptom among elderly Data were drawn from second wave China Health Retirement Longitudinal Study (CHARLS). Depressive symptoms assessed with a 10-item Center for Epidemiologic Studies–Depression Scale (CES-D), which was preselected CHARLS. The concentration index used magnitude...
China has three basic health insurance schemes: Urban Employee Basic Medical Insurance (UEBMI), Resident (URBMI) and New Rural Cooperative Scheme (NRCMS). This study aimed to compare the equity of health-related quality life (HRQoL) residents under any two schemes. Using data from 5th National Health Services Survey Shaanxi Province, China, coarsened exact matching method was employed control confounding factors. We included a matched sample 6802 respondents between UEBMI URBMI, 34,169...
China has been undergoing tremendous demographic and epidemiological transitions during the past three decades increasing burden from non-communicable diseases an ageing population have presented great health-care challenges for country. Numerous studies examine catastrophic healthcare expenditures (CHE) worldwide on whole populations rather than specific vulnerable groups. As hypertension other chronic conditions impose a growing share of disease in China, they will become increasingly...
The inequality of health human resource is a worldwide problem, and solving it also one the major goals China's recent system reform. Yet there huge disparity among cities in mainland China. aim this study to analyze distribution 322 prefecture-level China 2014, reveal facets causes inequalities. data for were acquired from provincial municipal Health Statistics Yearbook (2014) Statistical (2014), National Economic Bulletin official websites governments, involving cities. Meanwhile,...
Steroid resistant (SR) asthma is characterized by persistent airway inflammation that fails to resolve despite treatment with high doses of corticosteroids. Furthermore, SR patient airways show increased numbers neutrophils, which are less responsive glucocorticoid. The present study seeks determine whether dexamethasone (DEX) has different effect on neutrophils from steroid sensitive (SS) asthmatics compared asthmatics. Adults (n = 38) were classified as or SS based changes in lung FEV1%...
// Zun-yi Zhang 1 , Sheng-ling Fu Su-qin Xu 2 Xiao Zhou Xian-shen Liu Yong-jian Jian-ping Zhao Shuang Wei Department of Surgery, Tongji Hospital, Medical College Huazhong University Science and Technology, Wuhan 430030, China Respiratory Critical Care Medicine, Correspondence to: Wei, e-mail: wsdavid2001@163.com Keywords: hsa-miR-526b, Ku80, microRNA, NSCLC, p53 Received: August 24, 2014 Accepted: November Published: December 22, ABSTRACT Ku80 is involved in DNA double-strand breaks (DSBs)...
Introduction In 2009, China officially launched the New Health Care Reform (NHCR). One important purpose of reform was to reduce financial burden health care through insurance expansion and provider regulations. This study aimed provide evidence on effect NHCR catastrophic expenditure (CHE) by comparing occurrence inequality CHE among households with chronic diseases patients before after reform. Methods used subset data from 2008 2013 National Services Survey conducted in Shaanxi Province....
To improve equity in medical insurance benefits, the Chinese government integrated New Rural Cooperative Medical Scheme for rural residents and Urban Resident Basic Insurance nonworking urban into a unified system (URRBMI). This study aims to assess income-related mobility benefits before after integration of two schemes, explore its contribution improving equity. The panel data were obtained from 2011 2018 China Health Retirement Longitudinal Study, with 9,662 participants. received...
Lack of adequate dietary knowledge may result in poor health conditions. This study aims to measure income-related inequality knowledge, and explain the sources inequality. Data were from China Health Nutrition Survey (CHNS) conducted 2015. A summary score guideline awareness was used respondents. The concentration index employed as a socioeconomic decomposed into its determining factors. found that proportion respondents who correctly answered questions on significantly low for some...
The growing burden of COPD in the Asia-Pacific region supports need for more intensive research and analysis epidemiology to raise awareness disease its causes, ensure development effective national health policies facilitate equitable deployment finite health-care resources prevention management COPD. This study estimated compared mortality hospital morbidity rates trends these over time across countries regions Asia-Pacific.Data consistent with standard definitions (ICD-9/ICD-10) period...
Asthma is characterized by airway inflammation, mucus overproduction, hyperreactivity, and peribronchial fibrosis. Intelectin has been shown to be increased in epithelium of asthmatics. However, the role intelectin pathogenesis asthma unknown. Airway epithelial cells can secrete chemokines such as monocyte chemotactic protein (MCP)-1 -3 that play crucial roles asthmatic inflammation. We hypothesized plays a allergic inflammation regulating chemokine expression. In mouse model, we found mRNA...