A5101821238- Chronic Obstructive Pulmonary Disease (COPD) Research
- Obstructive Sleep Apnea Research
- Tracheal and airway disorders
- Liver Disease Diagnosis and Treatment
- Climate Change and Health Impacts
- Smoking Behavior and Cessation
- Neuroscience of respiration and sleep
- Healthcare and Venom Research
- Asthma and respiratory diseases
- Air Quality and Health Impacts
- Cardiovascular Disease and Adiposity
- Ginseng Biological Effects and Applications
- Menstrual Health and Disorders
- Digital Imaging for Blood Diseases
- Urban Green Space and Health
- Inflammasome and immune disorders
- Extenics and Innovation Methods
- Hepatitis B Virus Studies
- Noise Effects and Management
- Neurological Disease Mechanisms and Treatments
- Acute Ischemic Stroke Management
- Neonatal and fetal brain pathology
- Cancer-related Molecular Pathways
- Urban Heat Island Mitigation
- Cardiovascular and exercise physiology
National Clinical Research Center for Digestive Diseases
2018-2024
China-Japan Friendship Hospital
2018-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2024
Clinical Trial Investigators
2024
Guizhou Provincial People's Hospital
2019-2022
Peking University
2015-2021
Capital Medical University
2018-2021
Tangshan People's Hospital
2021
Peking Union Medical College Hospital
2020
Beijing Chao-Yang Hospital
2020
Abstract: Stimulator of interferon genes (STING1) is a key intermediary in activating the type I IFN response. STING-associated vasculopathy with onset infancy (SAVI) very rare autoinflammatory disease that caused by heterozygous gain-of-function mutations STING1. SAVI typically manifests as neonatal-onset systemic inflammation, interstitial lung (ILD), and severe cutaneous located acral regions, including fingers, toes, ears, nose. Severity ILD recurrent pulmonary infections are crucial for...
Background Maternal smoking during pregnancy (MSDP) is a known risk factor for offspring developing chronic obstructive pulmonary disease (COPD), but the underlying mechanism remains unclear. Objective This study aimed to explore whether increased COPD associated with MSDP could be attributed tobacco dependence (TD). Methods case-control used data from nationwide cross-sectional China Pulmonary Health study, controls matched age, sex, and status. TD was defined as within 30 minutes of...
At present, overseas and domestic eco-security early warning research is in the exploratory stage.This paper uses Kizilsu Kirghiz Autonomous Prefecture as object constructs an evaluation index system based on pressure-state-response (P-S-R) conceptual model.This study analyzes area using granger causality test model, entropy weight method, matter-element present situation future development trends area.The author hopes that this can further enrich provide a scientifi c reference for...
Abstract Background Continuous positive airway pressure (CPAP) is the most effective treatment for moderate to severe obstructive sleep apnea (OSA). Acceptance of and adherence CPAP are crucial optimal outcomes. The aim this study was investigate factors influencing patients’ acceptance treatment. Methods One hundred eighty‐eight patients with OSA who had received titration from October 2017 September 2018 were recruited. They interviewed at 2 weeks 6 months assess use barriers adherence....
The G870A polymorphism in the exon 4/intron 4 boundary of CCND1 gene is thought to influence generation two mRNAs (cyclin D1a and cyclin D1b). "A" allele codes for a truncated variant, D1b, which may have higher transforming activity. Herein, tumor relevance polymorphism, association between D1 variant expression genotype, oncogenic potential variants HBV-related hepatocellular carcinoma (HCC) were examined. We found that there no significant difference distribution among HCC, chronic HBV...
Background and Objective: Clinical population-based studies have demonstrated a strong association between obstructive sleep apnea (OSA) cardiovascular disease (CVD). Anatomical abnormalities of the craniofacial region upper airway are important risk factors for OSA. The objective this study was to investigate morphology with CVD biomarkers. Methods: One hundred sixty-nine male patients OSA underwent in-laboratory polysomnography (PSG) computed tomography (CT) scanning. Ten-year Framingham...
Despite the clinical and prognostic significance of obstructive sleep apnea (OSA) on chronic respiratory diseases, role interaction mechanism between upper lower airway for OSA prevalence in disease has not been clarified. Few studies have compared severity COPD fibrotic interstitial lung (ILD). The objectives this study were to identify physiological variables that predict occurrence ILD. 73 patients with 79 ILD studied prospective study. A full overnight PSG hospital setting, pulmonary...
<sec> <title>BACKGROUND</title> Maternal smoking during pregnancy (MSDP) is a known risk factor for offspring developing chronic obstructive pulmonary disease (COPD), but the underlying mechanism remains unclear. </sec> <title>OBJECTIVE</title> This study aimed to explore whether increased COPD associated with MSDP could be attributed tobacco dependence (TD). <title>METHODS</title> case-control used data from nationwide cross-sectional China Pulmonary Health study, controls matched age, sex,...
Fungal spores can be observed on peripheral blood smears and may affect cell counting in an automated hematology counter. The purpose of this study was to evaluate the effects fungal Sysmex-5000i counter.The common clinical we selected were C. albicans, krusei, tropicalis, glabrata, using 0.9% normal saline formulate a final concentration 4 - 6 x 109/L liquid, mixed with (containing high, medium low concentrations white cells platelets), formulated different (4 108/L, 107/L, 106/L,...
A decreased ventilatory response to hypoxia and hypercapnia is a common finding in patients with obesity hypoventilation syndrome (OHS). We aimed test the hypothesis that exercise also damaged OHS patients. Eleven OHS, twenty-three obese moderate-to-severe OSA twenty subjects without performed incremental cycle exercise. Oxygen consumption (VO2), ventilation (VE), equivalents for oxygen (VE/VO2) carbon dioxide (VE/VCO2), as well slope of VE/VO2 VE/VCO2 were measured. The VO2 was comparable...
Obstructive Sleep Apnea (OSA) is a sleep-related breathing disorder, with the incidence on rise nowadays. Gender and obesity are among predisposing factors for OSA. The aim of this study was to investigate gender difference OSA obese patients awaiting bariatric surgery possible influencing factors. In prospective study, standard overnight cardiorespiratory recording conducted in 252 subjects scheduled Bariatric Surgery. STOP-Bang, ESS questionnaires,pulmonary function, as well endocrine...