- Advanced Fluorescence Microscopy Techniques
- Robotic Path Planning Algorithms
- Robot Manipulation and Learning
- Soft Robotics and Applications
- Photoacoustic and Ultrasonic Imaging
- Robotics and Sensor-Based Localization
- Prosthetics and Rehabilitation Robotics
- Advanced Vision and Imaging
- Robotic Mechanisms and Dynamics
- Muscle activation and electromyography studies
- Ultrasound and Hyperthermia Applications
- Control and Dynamics of Mobile Robots
- Robotics and Automated Systems
- Image and Video Stabilization
- 3D Surveying and Cultural Heritage
- Image Processing Techniques and Applications
- Optical Coherence Tomography Applications
- Hand Gesture Recognition Systems
- Neuroscience and Neural Engineering
- Advanced Neural Network Applications
- Teleoperation and Haptic Systems
- Medical Image Segmentation Techniques
- Transcranial Magnetic Stimulation Studies
- Face recognition and analysis
- Optical Imaging and Spectroscopy Techniques
Hanyang University
2015-2024
Kwangwoon University
2019
ORCID
2018
Harvard University
2012-2017
Massachusetts General Hospital
2012-2017
Center for Systems Biology
2012-2017
Korea Institute of Science and Technology
2001-2015
Robotics Research (United States)
2012
The University of Tokyo
2008
Korea Institute of Robot and Convergence
2008
Skull stripping in brain magnetic resonance imaging (MRI) is an essential step to analyze images of the brain. Although manual segmentation has highest accuracy, it a time-consuming task. Therefore, various automatic algorithms MRI have been devised and proposed previously. However, there still no method that solves entire extraction problem satisfactorily for diverse datasets generic robust way. To address these shortcomings existing methods, we propose use 3D-UNet skull MRI. The was...
This paper presents an electromyographic (EMG)-based continuous control scheme including simple classifier for electric-powered wheelchair, ultimately quadriplegics. The proposed utilizes three EMG signals as inputs the muscle-computer interface. Since zygomaticus major muscles and transversus menti muscle of human face are able to move independently well adjust contractile forces voluntarily, surface on these utilized wheelchair system. To extract envelopes signal waveforms reflect moving...
This paper deals with target tracking control of unicycle type mobile robots. Target function is essential for autonomous robots such as guide robots, security guard etc. In the field robot control, many schemes posture stabilization and trajectory problem have been proposed. however, cannot be achieved using these kinds laws. Therefore, a new global asymptotic stable controller this designed backstepping method. The stability system proved Lyapunov function. Various simulation results...
Intravital fluorescence microscopy, through extended penetration depth and imaging resolution, provides the ability to image at cellular subcellular resolution in live animals, presenting an opportunity for new insights into vivo biology. Unfortunately, physiological induced motion components due respiration cardiac activity are major sources of artifacts impose severe limitations on effective that can be ultimately achieved vivo. Here we present a novel methodology capable automatically...
Skull stripping in brain magnetic resonance volume has recently been attracting attention due to an increased demand develop efficient, accurate, and general algorithm for diverse datasets of the brain. Accurate skull is a critical step neuroimaging diagnostic systems because neither inclusion non-brain tissues nor removal parts can be corrected subsequent steps, which results unfixed error through analysis. The objective this review article give comprehensive overview approaches, including...
We present an automatic technique for image alignment using a principal component analysis (PCA) that broadly consists of two steps. The first step is the segmentation region interest by thresholding. In second step, PCA applied on nonzero pixels in binary to determine object rotation about mean pixels. Existing PCA-based techniques align data their spread; however, they have critical problem 180° axes. This paper provides solution address this problem. algorithm based assignment rules...
This paper presents image stabilization for microscopy using horizontal visual feedback control of the objective lens through a five-bar linkage and piezoelectric actuators, its application to in vivo imaging. Even very small motion due heartbeat breathing makes microscopic observation difficult by blurring microscope or impossible sending region interest out view. In order remove those unwanted effects motion, we have introduced motion-canceling robotic technologies into microscopy. Our...
Motion artifacts continue to present a major challenge single cell imaging in cardiothoracic organs such as the beating heart, blood vessels, or lung. In this study, we new water-immersion suctioning stabilizer that enables minimally invasive intravital fluorescence microscopy using water-based stick objectives. The works by reducing motion excursions and can be used conjunction with both prospective retrospective gating approaches. We show approach offers cellular resolution murine heart...
Intravital microscopy has emerged in the recent decade as an indispensible imaging modality for study of micro-dynamics biological processes live animals. Technical advancements techniques and hardware components, combined with development novel targeted probes new mice models, have enabled us to address long-standing questions several biology areas such oncology, cell biology, immunology neuroscience. As instrument resolution increased, physiological motion activities become a major...
ABSTRACT Ultrasound application to neural tissues modifies their activity, and it is increasingly considered as a new mode of functional neuromodulation in both central peripheral nervous system. We investigate that ultrasound focused skin surface can induce differential sensations by modulating the activity sensory receptors. Pulsed was applied last digit human hands for 10 s using combinations acoustic frequencies (350 650 kHz), tone‐burst‐durations (0.1 1.0 ms), pulse repetition (10 100...
Head pose estimation is a fundamental function for several applications in human computer interactions. Accurate six degrees of freedom head (6DoF-HPE) with full-range angles make up most these applications, which require sequential images the as input. Most existing methods focus on three (3DoF) frontal head, restricts their real-world scenarios. This study presents framework designed to estimate without landmark localization. The novelty our 6DoF poses under real-time. proposed leverages...
Ultrasound is a promising neural stimulation modality, but an incomplete understanding of its range and mechanism effect limits therapeutic application. We investigated the modulation spontaneous hippocampal spike activity by ultrasound at lower acoustic intensity longer time scale than has been previously attempted, hypothesizing that spiking would change conditionally upon availability glutamate receptors. Using 60‐channel multielectrode array (MEA), we measured across organotypic rat...
An anthropomorphic prosthetic hand for wrist or forearm amputees is developed herein. The was designed with an underactuated mechanism, which makes self-adaptive grasping possible, as well natural motions such flexion and extension. finger thumb modules were four degrees of freedom by the distal interphalangeal, proximal metacarpophalangeal joints. In this research, we pursued several novel trials in design. By using two four-bar linkages composed a combination gears coupling joints at each...
There has been an increasing demand for robotic coil positioning during repetitive transcranial magnetic stimulation (rTMS) treatment. Accurate is crucial because rTMS generally targets specific brain regions both research and clinical application with other reasons such as safety, consistency reliability individual variablity. Some previous studies have employed industrial robots or co-robots showed they can more precisely stimulate the target cortical than traditional manual methods. In...
A major challenge in high-resolution intravital confocal and multiphoton microscopy is physiologic tissue movement during image acquisition. Of the various physiological sources of movement, respiration has arguably largest most wide-ranging effect. We describe a technique for achieving stabilized imaging using dual strategy. First, we designed mechanical stabilizer constraining physical motion; this served to simultaneously increase in-focus range over which data can be acquired as well...
Finger amputations are the most common upper limb amputation, and they occur approximately 100 times more often than hand amputations. We developed a prosthetic for amputees with thumb metacarpal. In this case of installation actuators electrical components is difficult because space considerably limited owing to residual This design issue solved by installing vertically between finger modules mounting part where parts embedded. With design, arrangement palm patient fingers can be adjusted...
Deals with the parking problem of a car-like mobile robot. The corresponds to point-stabilization nonholonomic systems. We propose simple and efficient algorithm for stability analysis. Using this algorithm, robot could be controlled move desired posture within prescribed boundary. performance is verified through simulations experiments using