A5101824273- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Advanced Fluorescence Microscopy Techniques
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Optical Coherence Tomography Applications
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Photoacoustic and Ultrasonic Imaging
- Colorectal Cancer Screening and Detection
- Anorectal Disease Treatments and Outcomes
- Genetic factors in colorectal cancer
- Pancreatitis Pathology and Treatment
- Metastasis and carcinoma case studies
- Helicobacter pylori-related gastroenterology studies
- Muscle and Compartmental Disorders
- Cancer, Lipids, and Metabolism
- Bone and Joint Diseases
- Monoclonal and Polyclonal Antibodies Research
- Ethics in medical practice
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Gut microbiota and health
- Rheumatoid Arthritis Research and Therapies
- Colorectal Cancer Treatments and Studies
Peking University
2016-2022
Peking University Cancer Hospital
2016-2022
Sixth Affiliated Hospital of Sun Yat-sen University
2021
Sun Yat-sen University
2021
Wuhan Union Hospital
2020-2021
Huazhong University of Science and Technology
2008-2020
Nanyang Technological University
2016-2017
Hainan General Hospital
2011
Tongji Hospital
2008
Shanghai Medical College of Fudan University
1997
Preoperative neoadjuvant chemoradiotherapy (nCRT) is a standard treatment for locally advanced rectal cancer (LARC) patients, yet little known about the mediators underlying heterogeneous patient response. In this longitudinal study, we performed 16S rRNA sequencing on 353 fecal specimens and find reduced microbial diversity after nCRT. Multi-omics data integration reveals that Bacteroides vulgatus-mediated nucleotide biosynthesis associates with nCRT resistance in LARC nonresponsive tumors...
To validate that a two-week short-course pre-operative radiotherapy regimen is feasible, safe, and effective for the management of elderly patients with locally advanced rectal cancer (LARC), we retrospectively analyzed 99 radiotherapy-naive ≥70 years age LARC. Patients received pelvic radiation therapy (3D-CRT 30Gy/10f/2w) followed by TME surgery; some adjuvant chemotherapy. The primary endpoint was OS, while secondary endpoints were DFS, safety response rate. median follow-up time 5.1...
The aim of this study was to explore the impact including or excluding ischiorectal fossa (IRF) within clinical target volume during neoadjuvant chemoradiotherapy (NCRT) using intensity modulated radiotherapy, in locally advanced lower rectal cancer (LALRC). We retrospectively analysed data 220 LALRC patients who received NCRT followed by abdominoperineal resection between January 2009 and 2015. Six were excluded because loss follow-up, 90 IRF irradiation (IRF group) while 124 did not (NIRF...
Purpose. In theory, the hyperfractionated radiotherapy can enhance biological effect dose against tumor and alleviate normal tissue toxicity. This study is to assess efficacy safety of preoperative intensity-modulated (IMRT) with oral capecitabine in patients locally advanced rectal cancer (LARC). Methods. We retrospectively screened LARC from January 2015 June 2016. Patients that received IMRT or conventional fractionated were eligible hyperfractionation (HF) group fractionation (CF) group,...
Objective To survey and compare the awareness attitude of hospice care among medical staff from hospitals ranked 1, 2, 3. And to examine association hospital grading with care. So that this study would promote orientation for theoretically. Methods A cross-sectional questionnaire was performed in Suzhou investigate Generalized linear regression model applied levels care. Results A total 990 individuals were surveyed. Among them, 580 3, 252 158 1. The someone self's death scored...
The feasibility of a constructed high-resolution OCT for cellular-level structures imaging in rat colon was evaluated the first time. Imaging results demonstrated that could be viable tool intestinal mucosa imaging.
Objective To reduce the misdiagnosis rate of spondyloarthritis (SpA) by reviewing rare cases misdiagnosed as SpA. Methods Cases SpA were collected from our hospital January 2004 to April 2014. Reported among Chinese journals 1998 October, 2014 also collected. According Assessment Spondylo Arthritis international Society (ASAS) axial criteria (2009) and peripheral (2011), diagnostic accordance was studied. Results There 112 within objective scope, out which, 27 (24.1%) infectious...
A 32 year-old woman in the third trimester of pregnancy was admitted for severe acute pancreatitis due to hypertriglyceridemia. During hospitalization she developed multiorgan dysfunction, infected pancreatic necrosis, abdominal compartment syndrome and intrauterine fetal death. She successfully treated by multidisciplinary team including department emergency medicine, ICU, gastroenterology, obstetrics, endocrinology, ultrasonography, radiology, infectious disease, nutrition...
Objective To assess the efficacy and safety of oxaliplatin combined with capecitabine in preoperative concurrent chemoradiotherapy for high-risk locally advanced rectal cancer. Methods We retrospectively screened patients adenocarcinoma rectum (T3 or T4 any N, T node positivity) Peking University Cancer Hospital Institute from March 2018 to February 2019. The eligible had at least one following factors: very low cancer, clinical T4b, mesorectal fascia involvement, positive extramural...
Pressure ulcers, also known as bed sores, are injury to the skin mainly caused by prolonged pressure, for example in someone who is bedridden. ulcers occur 470 3,210 per 10,000 patients hospitals U.K., U.S.A., and Canada. Their severity graded from stage 1 (the least severe) 4 most severe). For carers, it important know what normal regularly check changes over common places where pressure may appear (e.g. bottom, heels, lower back). Non‐blanching erythema – redness that does not turn white...
Abstract Background There is still controversial that whether hepatocellular carcinoma (HCC) patients with lymph node invasion should receive surgery treatment. This study to evaluate the efficacy of in HCC regional invasion. Methods The utilized data from Surveillance, Epidemiology, and End Results-18 (SEER-18) cancer registry. 1434 were included analysis. Among them, 168 treated surgically 1266 received non-surgery Propensity Score Matching (PSM) model was used reduce selection bias....
Abstract Purpose China is currently one of the countries with largest increased number new cancer cases in world, but pain management (CPM) still inadequate. This study, through a questionnaire designed to show knowledge, attitudes, and practices (KAP) status differences towards CPM among healthcare workers (HCWs) developed areas explore advantages role pharmacists mobile devices. Methods study used data from on March June 2019. The population consisted total 515 HCWs four first-tier cities...